Week 8 NFL Schedule & Opening Betting Odds

Seattle Seahawks quarterback Sam Darnold (14) throws during the second half of an NFL football game against the Arizona Cardinals Thursday, Sept. 25, 2025, in Glendale, Ariz.
(AP Photo/Ross D. Franklin)
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Below, bettors can find the opening NFL odds for the Week 8 NFL schedule.

The slate begins with Packers vs Panthers on TNF and culminates with Seahawks vs Bears on MNF. Notable Sunday games include Lions vs Vikings, Bills vs Ravens and Steelers vs Browns.

NFL Week 8 Opening Lines & Betting Odds

Thursday, October 29

Packers vs Panthers Odds

Sunday, November 1

Lions vs Vikings Odds

Jets vs Raiders Odds

Cowboys vs Cardinals Odds

Buccaneers vs Falcons Odds

Bills vs Ravens Odds

Jaguars vs Colts Odds

Bengals vs Titans Odds

Steelers vs Browns Odds

Rams vs Chargers Odds

Broncos vs Chiefs Odds

Dolphins vs Patriots Odds

Commanders vs Eagles Odds (SNF)

Seahawks vs Bears Odds (MNF)

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About the Author Read More @nickhennion

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.