San Francisco 49ers

49ers Week 1 Odds

How To Bet On San Francisco 49ers Odds

You can bet on spread, moneylines, over/under totals, parlays, and more San Francisco 49ers odds each season.

1. Visit the NFL odds page.
2. Find odds for the 49ers in a futures market (e.g., make the playoffs) or game market (e.g., 49ers vs. the Seahawks)
3. Add a bet to your Bet Slip.
4. Add a Stake to see the potential payout.
5. Place your bet!

If you’re in San Francisco and interested in odds for other teams, check out: 

• San Francisco Giants Odds
• Golden State Warriors Odds

San Francisco 49ers Futures Odds

Will the 49ers win the NFC West? Will they win the Super Bowl? How many interceptions will a certain player have this year?

For example: If you bet $20 on the 49ers (+200) to win the division, the bet would settle when the 49ers are eliminated or when they clinch the division.

San Francisco 49ers Spread

What’s the final scoring margin of the 49ers’ game?

For example: If you bet $200 on the 49ers -3.5 (-115) against the Carolina Panthers, San Francisco must win the game by at least four points. 

Alternatively, if you bet $200 on the 49ers +4.5 (-110) against the Philadelphia Eagles, San Francisco must lose by four or fewer points (or win the game).

If the scoring margin is identical to the spread (e.g., -2 or +7), the bet is a push, and your money is refunded.

San Francisco 49ers Moneyline

Will the 49ers win the matchup? 

For example: If you bet $50 on the 49ers -200 against the Miami Dolphins, San Francisco must win the game (in regulation or overtime).

If the game ends in a tie, the bet is a push.

San Francisco 49ers Over/Under Total

What is the number of points scored by both teams in the game? 

For example: If you bet $15 on over 49.5 (-110) in their game against the Detroit Lions, the teams must combine for at least 50 points. 

Alternatively, if you bet $25 on under 29.5 (-110), the teams must combine for 29 or fewer points.

If the combined point total is identical to the over/under total, the bet is a push.

San Francisco 49ers Parlays

You can combine 49ers’ bets and other NFL bets into one parlay.

For example: If you bet $10 on a three-leg parlay with the 49ers’ moneyline (+110) vs. the Buffalo Bills, Falcons’ moneyline (-125 vs. the Las Vegas Raiders), and over 49.5 (-115) in the Pittsburgh Steelers-Cincinnati Bengals game, all three legs must hit for the bet to cash.

If one bet is a push, it’s eliminated from the parlay, and odds (and payout) are recalculated without that leg.