With many leagues now playing a nine-game conference schedule, this week’s slate of college football odds will include many more impactful games than the previous two weeks.
Still, there are teams out there that are dipping into G6 or FCS competition. And in those cases, many of the point spreads remain pretty massive.
These are the biggest favorites on the board as of Wednesday – with FBS vs. FCS games yet to be priced.
North Dakota State -27.5 vs. Sacramento State
Utah -27.5 vs. Utah State
Notre Dame -29.5 vs. Michigan State
Texas -30 vs. UTSA
Arizona -34.5 vs. Northern Illinois
Michigan -35 vs. UTEP
Tennessee -35.5 vs. Kennesaw State
Penn State -40.5 vs. Buffalo
Indiana -44.5 vs. Western Kentucky
Ohio State -52.5 vs. Kent State
Biggest Favorites For College Football Week 3 (2026)
- Ohio State -52.5 vs Kent State
- Indiana -44.5 vs Western Kentucky
- Penn State -40.5 vs Buffalo
- Tennessee -35.5 vs Kennesaw State
- Michigan -35 vs. UTEP
- Arizona -34.5 vs Northern Illinois
- Texas -30 vs UTSA
- Notre Dame -29.5 vs. Michigan State
- Utah -27.5 vs Utah State
- NDSU -27.5 vs. Sac State
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