• The Blue Jays are -125 favorites vs the Astros
• Astros vs Blue Jays Over / Under today: 7.5 Runs
• Astros / Blue Jays TV Channel: SCHN | RSN | TVA

The Houston Astros (+105) visit Rogers Centre to take on the Toronto Blue Jays (-125) on June 22, 2026. First pitch is scheduled for 7:07 pm in Toronto, ON.

This season, the Astros are 37-42 against the spread (ATS), while the Blue Jays are 39-37 ATS.

Astros vs Blue Jays Starting Pitchers Today:

• Astros starting pitcher: Hunter Brown 1-0, 1.13 ERA
• Blue Jays starting pitcher: Dylan Cease 4-3, 2.71 ERA

Astros vs. Blue Jays Odds, Run Line, Over/Under & Moneyline

Astros vs Blue Jays Prediction for Today’s Game

Based on recent trends the model predicts the Blue Jays will win Monday‘s MLB game with 57.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Astros vs Blue Jays and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Astros players for Monday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Bets Today:

• Jose Altuve has hit the Home Runs Over in 3 of his last 7 games (+13.80 Units / 197% ROI)
• Jeremy Pena has hit the Total Bases Under in 16 of his last 20 away games (+10.15 Units / 33% ROI)
• Isaac Paredes has hit the Singles Under in 19 of his last 25 games (+8.70 Units / 22% ROI)
• Yainer Diaz has hit the Hits Runs and RBIs Over in 17 of his last 25 away games (+8.65 Units / 30% ROI)
• Cam Smith has hit the Hits Over in 12 of his last 15 away games (+7.40 Units / 32% ROI)

And here are some favorite MLB player prop bets for Blue Jays players for Monday‘s game, looking at profitable historical betting trends:

Best Blue Jays Player Prop Best Bets Today:

• Nathan Lukes has hit the Hits Over in 21 of his last 25 games (+17.25 Units / 39% ROI)
• Nathan Lukes has hit the Total Bases Over in 17 of his last 25 games (+12.95 Units / 46% ROI)
• Davis Schneider has hit the Hits Runs and RBIs Under in 15 of his last 20 games at home (+10.30 Units / 45% ROI)
• Davis Schneider has hit the Home Runs Over in 2 of his last 5 games (+9.80 Units / 196% ROI)
• Davis Schneider has hit the Runs Under in 13 of his last 15 games at home (+8.85 Units / 28% ROI)

Astros Best Bets Today:

• The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 24 of their last 40 away games (+7.30 Units / 16% ROI)
• The Houston Astros have hit the Moneyline in 14 of their last 23 away games (+7.20 Units / 30% ROI)
• The Houston Astros have hit the Team Total Over in 9 of their last 13 away games (+5.30 Units / 36% ROI)
• The Houston Astros have hit the Game Total Under in 12 of their last 22 away games (+4.35 Units / 18% ROI)
• The Houston Astros have covered the Run Line in 18 of their last 30 games (+4.25 Units / 10% ROI)

Blue Jays Best Bets Today:

• The Toronto Blue Jays have covered the Run Line in 24 of their last 40 games (+8.05 Units / 15% ROI)
• The Toronto Blue Jays have hit the Game Total Over in 18 of their last 30 games at home (+6.10 Units / 19% ROI)
• The Toronto Blue Jays have hit the 1st Five Innings (F5) Team Total Under in 26 of their last 45 games at home (+5.80 Units / 11% ROI)
• The Toronto Blue Jays have hit the Moneyline in 20 of their last 35 games (+5.30 Units / 13% ROI)
• The Toronto Blue Jays have covered the 1st Five Innings (F5) Run Line in 6 of their last 8 games (+3.60 Units / 36% ROI)

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 37-42 against the Run Line (-11.2 Units / -10.52% ROI).

• 37-42 when betting on the Moneyline for -6.6 Units / -7.24% ROI
• 42-33 when betting on the total runs Over for +4.75 Units / 5.38% ROI
• 33-42 when betting on the total runs Under for -12.9 Units / -15.09% ROI

Blue Jays Against the Spread (ATS) Record

Against the spread this season, the Blue Jays are 39-37 against the Run Line (-1.3 Units / -1.29% ROI).

• 38-39 when betting on the Moneyline for -7.95 Units / -8.15% ROI
• 38-36 when betting on the total runs Over for -1.35 Units / -1.6% ROI
• 36-38 when betting on the total runs Under for -5.6 Units / -6.6% ROI

Blue Jays vs Astros Home Run Prop Bets Today

Blue Jays vs Astros Total Hits Prop Bets Today

Blue Jays vs Astros Strikeout Prop Bets Today

Astros Keys to the Game vs. the Blue Jays

The Astros are just 2-37 (.051) when trailing entering the 7th inning this season — 3rd lowest in MLB; League Avg: .140.

The Astros are 34-0 (1.000) when leading entering the 9th inning this season — tied for best in MLB; League Avg: .945.

The Astros are just 7-20 (.259) when their opponents score in the first inning this season — 5th lowest in MLB; League Avg: .357.

The Astros are 6-3 (.667) when tied entering the 7th inning this season — tied for 4th best in MLB; League Avg: .500.

Blue Jays Keys to the Game vs. the Astros

The Blue Jays are 6-30 (.167) when trailing entering the 8th inning this season — 4th best in MLB; League Avg: .105.

The Blue Jays are 18-83 (.178) when trailing entering the 8th inning since the 2025 season — best in MLB; League Avg: .095.

The Blue Jays are 21-80 (.208) when trailing entering the 7th inning since the 2025 season — 2nd best in MLB; League Avg: .129.

The Blue Jays are 94-11 (.895) when scoring 5 or more runs since the 2025 season — 2nd best in MLB; League Avg: .796.

Astros Hitting Stats & Trends

Astros hitters have an OPS of .745 (1,474 PA’s) on the road this season — 5th best in MLB.

29% of Astros hitters strikeouts have come on 95+ MPH fastballs this season — 5th highest in MLB.

Astros hitters are slugging just .184 on pitches out of the zone this season — tied for 4th lowest in MLB.

Astros hitters have struck out in just 17% of their PA’s in lefty-lefty matchups this season — 2nd best in MLB.

Blue Jays Hitting Stats & Trends

The Blue Jays are batting .192 with two-strikes this season — best in MLB.

Blue Jays hitters have struck out in just 19% of their PA’s against RHP this season — best in MLB.

Blue Jays hitters have a swing rate of 64% with two-strikes this season — highest in MLB.

Blue Jays hitters have chased 47% of pitches out of the zone with two-strikes this season — highest in MLB.

Astros Pitching Stats & Trends

Astros pitchers have walked 11% of batters this season — 3rd highest in MLB.

Astros pitchers have walked 12% of batters when facing the leadoff batter in the inning this season — highest in MLB.

Opponents have a groundball rate of just 40% against Astros pitchers this season — tied for 2nd lowest in MLB.

Astros pitchers have a first-pitch strike rate of just 59% this season — 3rd lowest in MLB.

Blue Jays Pitching Stats & Trends

Blue Jays pitchers have allowed an average Exit Velocity of 87.7 MPH (1,866 batted balls) this season — 2nd best in MLB.

Blue Jays pitchers have 131 three-pitch strikeouts this season — 2nd most in MLB.

The Blue Jays pitchers have allowed an average Exit Velocity of just 87.7 MPH this season (1,866 balls in play) — 2nd best in MLB

Blue Jays pitchers have allowed an exit velocity of 95 MPH or greater 693 times this season — 4th fewest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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