- The Padres are -125 favorites vs the Cubs
- Cubs vs Padres Over / Under today: 7.5 Runs
- Cubs / Padres TV Channel: PEAC | NBCS
The Chicago Cubs (+105) visit Petco Park to take on the San Diego Padres (-125) on September 29, 2026. First pitch is scheduled for 10:00 pm in San Diego, CA.
This season, the Cubs are 89-73 against the spread (ATS), while the Padres are 89-70 ATS.
Cubs vs Padres Starting Pitchers Today:
- Cubs starting pitcher: Matthew Boyd 10-5, 3.96 ERA
- Padres starting pitcher: Michael King 12-10, 3.21 ERA
Cubs vs. Padres Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Cubs | +1.5 -210 | O 7.5 -125 | +105 |
| Padres | -1.5 +170 | U 7.5 +105 | -125 |
Cubs vs Padres Prediction for Today’s Game
Based on recent trends the model predicts the Padres will win Tuesday‘s MLB game with 54.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
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We’ve highlighted some favorite MLB player prop bets for Cubs players for Tuesday‘s game, looking at profitable historical betting trends:
Best Cubs Player Prop Bets Today:
- Michael Conforto has hit the Runs Under in 18 of his last 20 games (+14.35 Units / 36% ROI)
- Matthew Boyd has hit the Walks Allowed Over in 18 of his last 25 games (+12.50 Units / 39% ROI)
- Ian Happ has hit the Hits Runs and RBIs Over in 17 of his last 25 games (+10.30 Units / 39% ROI)
- Michael Busch has hit the Walks Over in 10 of his last 15 away games (+9.75 Units / 65% ROI)
- Dansby Swanson has hit the Hits Under in 15 of his last 25 games (+9.15 Units / 36% ROI)
And here are some favorite MLB player prop bets for Padres players for Tuesday‘s game, looking at profitable historical betting trends:
Best Padres Player Prop Best Bets Today:
- Michael King has hit the Pitching Outs Over in 19 of his last 25 games (+11.85 Units / 38% ROI)
- Jake Cronenworth has hit the Home Runs Over in 2 of his last 9 games at home (+11.00 Units / 122% ROI)
- Fernando Tatis Jr. has hit the Runs Over in 18 of his last 25 games (+10.75 Units / 33% ROI)
- Manny Machado has hit the Hits Under in 12 of his last 20 games (+8.90 Units / 38% ROI)
- Jackson Merrill has hit the Hits Runs and RBIs Over in 17 of his last 25 games at home (+8.85 Units / 31% ROI)
Cubs Best Bets Today:
- The Chicago Cubs have covered the Run Line in 31 of their last 50 away games (+15.20 Units / 25% ROI)
- The Chicago Cubs have hit the Game Total Over in 31 of their last 50 games (+13.45 Units / 24% ROI)
- The Chicago Cubs have hit the Team Total Over in 32 of their last 50 away games (+11.40 Units / 19% ROI)
- The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 17 of their last 30 games (+9.95 Units / 23% ROI)
- The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 19 of their last 30 games (+7.35 Units / 21% ROI)
Padres Best Bets Today:
- The San Diego Padres have hit the Moneyline in 33 of their last 45 games at home (+19.30 Units / 32% ROI)
- The San Diego Padres have hit the Team Total Over in 16 of their last 18 games (+13.85 Units / 67% ROI)
- The San Diego Padres have covered the Run Line in 28 of their last 45 games (+13.15 Units / 23% ROI)
- The San Diego Padres have hit the 1st Five Innings (F5) Team Total Over in 16 of their last 20 games (+12.35 Units / 53% ROI)
- The San Diego Padres have hit the 1st Five Innings (F5) Moneyline in 15 of their last 20 games (+12.15 Units / 43% ROI)
Cubs Against the Spread (ATS) Record
Against the spread this season, the Cubs are 76-84 against the Run Line (-3.65 Units / -1.94% ROI).
- 89-73 when betting on the Moneyline for -5.55 Units / -2.51% ROI
- 90-68 when betting on the total runs Over for +15.85 Units / 8.87% ROI
- 68-90 when betting on the total runs Under for -30.3 Units / -17.03% ROI
Padres Against the Spread (ATS) Record
Against the spread this season, the Padres are 89-70 against the Run Line (+13.95 Units / 6.58% ROI).
- 91-71 when betting on the Moneyline for +14.85 Units / 7.43% ROI
- 77-80 when betting on the total runs Over for -11.1 Units / -6.2% ROI
- 80-77 when betting on the total runs Under for -4.05 Units / -2.28% ROI
Cubs Keys to the Game vs. the Padres
The Cubs are 49-6 (.891) when they’ve had 10 or more hits this season — 2nd best in MLB.
The Cubs are 18-30 (.375) when allowing 10 or more hits this season — best in MLB.
The Cubs are 6-65 (.085) when trailing entering the 9th inning this season — 2nd best in MLB.
The Cubs are 40-4 (.909) when they’ve had 5 or more XBH this season — 5th best in MLB.
Padres Keys to the Game vs. the Cubs
The Padres are 65-8 (.890) when scoring 5 or more runs this season — 2nd best in MLB.
The Padres are 26-21 (.553) vs the top 10 runs allowed teams this season Today, they face Cubs (12th fewest runs allowed).
The Padres are 51-30 (.630) at home this season — tied for 4th best in MLB.
The Padres are 66-5 (.930) when leading entering the 7th inning this season — 2nd best in MLB.
Cubs Hitting Stats & Trends
Cubs hitters have an OPS of .795 (1,699 PA’s) against LHP this season — best in MLB.
Cubs hitters are slugging .507 on breaking pitches against LHP this season — best in MLB.
Cubs hitters have an OBP of .370 (638 PA’s) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.
Cubs hitters have an OBP of .349 (1,699 PA’s) against LHP this season — best in MLB.
Padres Hitting Stats & Trends
The Padres have won 94% of home games in which they have scored three or more runs in an inning this season — 2nd highest in MLB.
The Padres are batting .251 with two outs this season — 3rd best in MLB.
The Padres are batting .368 on the first pitch of at-bats this season — 2nd best in MLB.
Padres hitters are slugging .413 on the road this season — 5th best in MLB.
Cubs Pitching Stats & Trends
Cubs pitchers have picked-off 24 runners from first base this season — most in MLB.
Opponents have a groundball batting average of just .214 against Cubs pitchers with runners on base this season — best in MLB.
Cubs pitchers have picked-off 24 runners this season — most in MLB.
Opponents have a groundball batting average of just .224 against Cubs pitchers this season — best in MLB.
Padres Pitching Stats & Trends
Padres pitchers have an ERA of 3.50 (743.0 IP) at home this season — 3rd best in MLB.
Padres pitchers have won 35% of games in which they have allowed their opponent to score in three different innings this season — 2nd highest in MLB.
The Padres have allowed 3.79 runs per game (307/81) at home this season — 3rd best in MLB.
The Padres have won 46% of home games in which their opponents scored first this season — 2nd highest in MLB.
More MLB Reading:
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