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The Padres odds to win the World Series are +2000.
World Series Favorites
The Padres odds to win the NL pennant are +1200.
NL Pennant Favorites
The Padres NL West champion odds are +650
NL West Odds
The Padres odds to make the playoffs are -200. Their odds to miss the playoffs are +165.
A breakdown of the updated MLB 2025 World Series odds, including betting favorites and best betting predictions for the Fall Classic. Read More
The Tampa Bay Rays (-105) visit Petco Park to take on the San Diego Padres (-115) on Sunday, April 27, 2025. First pitch is scheduled for 4:10pm EDT in San Diego, CA, CA. This season, the Rays are 13- Read More
The Tampa Bay Rays (+110) visit Petco Park to take on the San Diego Padres (-135) on Saturday, April 26, 2025. First pitch is scheduled for 8:40pm EDT in San Diego, CA, CA. This season, the Rays are 1 Read More
The Tampa Bay Rays (+120) visit Petco Park to take on the San Diego Padres (-145) on Friday, April 25, 2025. First pitch is scheduled for 9:40pm EDT in San Diego, CA, CA. This season, the Rays are 11- Read More
Here are updated odds, insights, picks, and analysis for the AL & NL MVP Awards during the 2025 MLB season. Read More
The San Diego Padres (+140) visit Comerica Park to take on the Detroit Tigers (-170) on Wednesday, April 23, 2025. First pitch is scheduled for 1:10pm EDT in Detroit, MI, MI. This season, the Padres a Read More
The San Diego Padres (-105) visit Comerica Park to take on the Detroit Tigers (-115) on Tuesday, April 22, 2025. First pitch is scheduled for 6:40pm EDT in Detroit, MI, MI. This season, the Padres are Read More
Find out which Padres players are scheduled to hit free agency and be eligible for arbitration after the 2025 MLB season. Read More
The San Diego Padres (+120) visit Comerica Park to take on the Detroit Tigers (-145) on Monday, April 21, 2025. First pitch is scheduled for 6:40pm EDT in Detroit, MI, MI. This season, the Padres are Read More
Run lines, over/under totals, moneylines, and more odds are available for each Padres game this season.
If you’re in California and interested in odds for other teams, check out:
Will the Padres win the NL West? Will they win the NL pennant? How many RBIs will a certain player hit this season?
For example: If you bet $50 on the Padres (+550) to make the postseason, the bet would settle when San Diego is eliminated or when they clinch a postseason berth.
The run line is baseball’s version of the spread. What’s the final scoring margin of the game?
For example: If you bet $35 on the Padres -1.5 (+120) against the Arizona Diamondbacks, San Diego must win the game by at least two runs.
Alternatively, if you bet $35 on the Padres +1.5 (-150) against the Atlanta Braves, San Diego must lose by one run (or win the game).
Will the Padres win the game?
For example: If you bet $65 on the Padres -200 against the Toronto Blue Jays, San Diego must win the game (in nine innings or extra innings).
How many combined runs will be scored by both teams in the matchup?
For example: If you bet $30 on over 8.5 (-115) in their game against the Cincinnati Reds, the teams must combine for at least nine runs.
Alternatively, if you bet $40 on under 8.5 (-105), the teams must combine for eight or fewer runs.
If the combined run total is the same as the over/under total, the bet is a push.
You can combine bets and other bets — baseball or another sport — into one parlay.
For example: If you bet $15 on a two-leg parlay with the Padres moneyline (-160) vs. the Minnesota Twins and over 7.5 (-105) in the Chicago Cubs-Miami Marlins game, both must hit for the bet to cash.
If one bet is a push, it’s eliminated from the parlay, and odds (and payout) are recalculated without that leg.
