• The Guardians are -125 favorites vs the Blue Jays
• Guardians vs Blue Jays Over / Under today: 8 Runs
• Guardians / Blue Jays TV Channel: GDTV | RSN1

The Cleveland Guardians (-125) visit Rogers Centre to take on the Toronto Blue Jays (+105) on April 24, 2026. First pitch is scheduled for 7:07 pm in Toronto, ON.

This season, the Guardians are 14-12 against the spread (ATS), while the Blue Jays are 8-16 ATS.

Guardians vs Blue Jays Starting Pitchers Today:

• Guardians starting pitcher: Gavin Williams 3-1, 2.10 ERA
• Blue Jays starting pitcher: Max Scherzer 1-2, 7.48 ERA

Guardians vs. Blue Jays Odds, Run Line, Over/Under & Moneyline

Guardians vs Blue Jays Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Friday‘s MLB game with 52.5% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Guardians players for Friday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

• Brayan Rocchio has hit the Home Runs Over in 2 of his last 9 games (+16.00 Units / 178% ROI)
• Ernie Clement has hit the Hits Over in 19 of his last 25 games (+12.85 Units / 29% ROI)
• Gavin Williams has hit the Hits Allowed Under in 16 of his last 20 games (+11.85 Units / 50% ROI)
• Ernie Clement has hit the Total Bases Over in 16 of his last 25 away games (+11.35 Units / 40% ROI)
• Ernie Clement has hit the Singles Over in 16 of his last 20 away games (+10.35 Units / 38% ROI)

And here are some favorite MLB player prop bets for Blue Jays players for Friday‘s game, looking at profitable historical betting trends:

Best Blue Jays Player Prop Best Bets Today:

• Vladimir Guerrero Jr has hit the RBIs Under in 16 of his last 20 games at home (+9.30 Units / 25% ROI)
• Vladimir Guerrero Jr has hit the Singles Over in 18 of his last 25 games (+9.25 Units / 28% ROI)
• Kazuma Okamoto has hit the Total Bases Under in 13 of his last 20 games (+7.50 Units / 33% ROI)
• Kazuma Okamoto has hit the Runs Under in 16 of his last 20 games (+7.15 Units / 19% ROI)
• Kazuma Okamoto has hit the Hits Under in 9 of his last 15 games (+4.50 Units / 30% ROI)

Guardians Best Bets Today:

• The Cleveland Guardians have hit the Moneyline in 32 of their last 50 games (+15.75 Units / 26% ROI)
• The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 33 of their last 50 away games (+14.00 Units / 23% ROI)
• The Cleveland Guardians have covered the Run Line in 30 of their last 50 games (+13.35 Units / 21% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Moneyline in 14 of their last 25 away games (+9.35 Units / 36% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Under in 28 of their last 45 games (+8.80 Units / 16% ROI)

Blue Jays Best Bets Today:

• The Toronto Blue Jays have hit the 1st Five Innings (F5) Team Total Under in 19 of their last 24 games (+14.30 Units / 49% ROI)
• The Toronto Blue Jays have hit the Team Total Over in 27 of their last 45 games at home (+7.40 Units / 14% ROI)
• The Toronto Blue Jays have covered the 1st Five Innings (F5) Run Line in 16 of their last 25 games at home (+5.50 Units / 19% ROI)
• The Toronto Blue Jays have hit the 1st Five Innings (F5) Moneyline in 14 of their last 25 games at home (+3.90 Units / 10% ROI)
• The Toronto Blue Jays have hit the Game Total Over in 24 of their last 45 games (+2.30 Units / 5% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 14-12 against the Run Line (+2.5 Units / 7.78% ROI).

• 14-12 when betting on the Moneyline for +3.4 Units / 11.35% ROI
• 13-13 when betting on the total runs Over for -1.1 Units / -3.85% ROI
• 13-13 when betting on the total runs Under for -1.35 Units / -4.69% ROI

Blue Jays Against the Spread (ATS) Record

Against the spread this season, the Blue Jays are 8-16 against the Run Line (-9.55 Units / -32.93% ROI).

• 10-14 when betting on the Moneyline for -10.1 Units / -28.73% ROI
• 12-12 when betting on the total runs Over for -1.2 Units / -4.53% ROI
• 12-12 when betting on the total runs Under for -1.1 Units / -4.18% ROI

Blue Jays vs Guardians Home Run Prop Bets Today

Blue Jays vs Guardians Total Hits Prop Bets Today

Blue Jays vs Guardians Strikeout Prop Bets Today

Guardians Keys to the Game vs. the Blue Jays

The Guardians are 10-1 (.909) after a loss this season — best in MLB; League Avg: .478.

The Guardians were 33-4 (.868) when they had 10 or more hits in the 2025 season — 2nd best in MLB; League Avg: .743.

The Guardians are just 0-11 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .050.

The Guardians are 26-3 (.897) when they’ve had 5 or more XBH since the 2025 season — 3rd best in MLB; League Avg: .798.

Blue Jays Keys to the Game vs. the Guardians

The Blue Jays are 78-5 (.940) when scoring 5 or more runs since the 2025 season — best in MLB; League Avg: .792.

The Blue Jays were 71-4 (.947) when they scored 5 or more runs in the 2025 season — best in MLB; League Avg: .797.

The Blue Jays were 15-51 (.227) when trailing entering the 7th inning in the 2025 season — 2nd best in MLB; League Avg: .124.

The Blue Jays are 14-64 (.179) when trailing entering the 8th inning since the 2025 season — best in MLB; League Avg: .092.

Guardians Hitting Stats & Trends

The Guardians are batting just .194 in righty-righty matchups since the 2025 season — lowest in MLB.

Guardians hitters are averaging 4.17 pitches per plate appearance this season — highest in MLB.

Guardians hitters have put just 28% of their swings in play on the first pitch of at-bats this season — lowest in MLB.

Guardians hitters had a Hard-Hit Rate of just 36% in the 2025 season — lowest in MLB.

Blue Jays Hitting Stats & Trends

Blue Jays hitters struck out in just 18% of their PA’s in the 2025 season — best in MLB.

Blue Jays hitters have struck out in just 18% of their PA’s against LHP since the 2025 season — best in MLB.

Blue Jays hitters have struck out in just 14% of their PA’s against LHP this season — best in MLB.

The Blue Jays are batting .184 on pitches out of the zone since the 2025 season — best in MLB.

Guardians Pitching Stats & Trends

Guardians pitchers have a strikeout rate of 37% in close and late situations this season — best in MLB.

Guardians pitchers have a strikeout rate of 25% this season — tied for 2nd best in MLB.

Guardians pitchers had an ERA of 2.54 (471.1 IP) against division opponents in the 2025 season — best in MLB.

Opponents had a chase percentage of just 26% against the Guardians pitchers in the 2025 season — lowest in MLB.

Blue Jays Pitching Stats & Trends

Blue Jays pitchers won 45% of games in which they allowed their opponent to score in three different innings in the 2025 season — highest in MLB.

Blue Jays pitchers have a strikeout rate of 31% versus the bottom of the order this season — best in MLB.

Blue Jays pitchers have a strikeout rate of 47% with two-strikes this season — best in MLB.

Blue Jays pitchers have struck out 27% of left-handed batters they faced this season — best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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