• The Padres are +110 favorites vs the Brewers
• Padres vs Brewers Over / Under today: 8.5 Runs
• Padres / Brewers TV Channel: BRTV | PDTV

The San Diego Padres (+110) visit American Family Field to take on the Milwaukee Brewers (-130) on May 12, 2026. First pitch is scheduled for 7:40 pm in Milwaukee, WI.

This season, the Padres are 24-16 against the spread (ATS), while the Brewers are 24-14 ATS.

Padres vs Brewers Starting Pitchers Today:

• Padres starting pitcher: Matt Waldron 1-1, 7.72 ERA
• Brewers starting pitcher: Brandon Sproat 0-2, 5.87 ERA

Padres vs. Brewers Odds, Run Line, Over/Under & Moneyline

Padres vs Brewers Prediction for Today’s Game

Based on recent trends the model predicts the Brewers will win Tuesday‘s MLB game with 56.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Padres vs Brewers and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Padres players for Tuesday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Bets Today:

• Xander Bogaerts has hit the Home Runs Over in 2 of his last 5 away games (+14.90 Units / 298% ROI)
• Manny Machado has hit the Hits Under in 14 of his last 20 away games (+13.35 Units / 52% ROI)
• Jackson Merrill has hit the Hits Runs and RBIs Under in 16 of his last 20 games (+12.50 Units / 55% ROI)
• Manny Machado has hit the Total Bases Under in 20 of his last 25 away games (+12.35 Units / 32% ROI)
• Gavin Sheets has hit the Singles Under in 19 of his last 25 games (+11.25 Units / 32% ROI)

And here are some favorite MLB player prop bets for Brewers players for Tuesday‘s game, looking at profitable historical betting trends:

Best Brewers Player Prop Best Bets Today:

• Sal Frelick has hit the Home Runs Over in 2 of his last 4 games at home (+17.00 Units / 425% ROI)
• Jake Bauers has hit the Hits Runs and RBIs Over in 13 of his last 15 games at home (+11.95 Units / 70% ROI)
• Jake Bauers has hit the Runs Over in 11 of his last 15 games at home (+10.70 Units / 71% ROI)
• Jake Bauers has hit the Hits Over in 13 of his last 15 games at home (+10.60 Units / 50% ROI)
• Sal Frelick has hit the Total Bases Under in 11 of his last 15 games at home (+9.35 Units / 52% ROI)

Padres Best Bets Today:

• The San Diego Padres have hit the Team Total Under in 16 of their last 21 games (+10.45 Units / 43% ROI)
• The San Diego Padres have hit the Moneyline in 31 of their last 50 games (+8.35 Units / 13% ROI)
• The San Diego Padres have hit the Game Total Under in 29 of their last 50 games (+8.25 Units / 15% ROI)
• The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in 10 of their last 13 away games (+6.65 Units / 41% ROI)
• The San Diego Padres have covered the Run Line in 20 of their last 35 games (+4.95 Units / 11% ROI)

Brewers Best Bets Today:

• The Milwaukee Brewers have covered the Run Line in 22 of their last 35 games at home (+13.60 Units / 33% ROI)
• The Milwaukee Brewers have hit the Team Total Over in 32 of their last 50 games at home (+11.15 Units / 19% ROI)
• The Milwaukee Brewers have hit the 1st Five Innings (F5) Team Total Over in 30 of their last 50 games at home (+9.15 Units / 16% ROI)
• The Milwaukee Brewers have hit the 1st Five Innings (F5) Moneyline in 28 of their last 50 games at home (+6.75 Units / 9% ROI)
• The Milwaukee Brewers have covered the 1st Five Innings (F5) Run Line in 29 of their last 50 games at home (+5.55 Units / 9% ROI)

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 21-18 against the Run Line (+1.8 Units / 3.45% ROI).

• 24-16 when betting on the Moneyline for +4.7 Units / 9.06% ROI
• 16-22 when betting on the total runs Over for -8.05 Units / -18.27% ROI
• 22-16 when betting on the total runs Under for +4.55 Units / 10.34% ROI

Brewers Against the Spread (ATS) Record

Against the spread this season, the Brewers are 24-14 against the Run Line (+13.7 Units / 30.01% ROI).

• 22-16 when betting on the Moneyline for +0.75 Units / 1.52% ROI
• 18-19 when betting on the total runs Over for -2.95 Units / -7.02% ROI
• 19-18 when betting on the total runs Under for -0.7 Units / -1.68% ROI

Brewers vs Padres Home Run Prop Bets Today

Brewers vs Padres Total Hits Prop Bets Today

Brewers vs Padres Strikeout Prop Bets Today

Padres Keys to the Game vs. the Brewers

The Padres are 3-16 (.158) when trailing entering the 9th inning this season — best in MLB; League Avg: .051.

The Padres are 15-1 (.938) when scoring 5 or more runs this season — 3rd best in MLB; League Avg: .789.

The Padres are 11-6 (.647) on the road this season — 3rd best in MLB; League Avg: .463.

The Padres are 6-5 (.545) vs the top 10 runs allowed teams this season Today, they face Brewers (fourth in runs allowed).

Brewers Keys to the Game vs. the Padres

The Brewers are 14-7 (.667) after a win this season — 3rd best in MLB; League Avg: .530.

The Brewers are 3-10 (.231) when trailing entering the 8th inning this season — 4th best in MLB; League Avg: .106.

The Brewers are just 0-11 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .051.

The Brewers are 8-2 (.800) when they’ve scored in the first inning this season — 5th best in MLB; League Avg: .626.

Padres Hitting Stats & Trends

Padres hitters have an OBP of just .276 (824 PA’s) against starting pitchers this season — lowest in MLB.

Padres hitters have an OPS of just .607 (824 PA’s) against starting pitchers this season — lowest in MLB.

Padres hitters are slugging just .336 against LHP this season — 5th lowest in MLB.

Padres hitters have an OBP of just .298 (1,182 PA’s) against RHP this season — 4th lowest in MLB.

Brewers Hitting Stats & Trends

Brewers hitters are slugging just .298 against LHP this season — 2nd lowest in MLB.

Brewers hitters have come to the plate with runners in scoring position in 448 of their 1,479 plate appearances (30%) this season — 2nd highest in MLB.

Brewers hitters have a Hard-Hit Rate of just 32% on the first pitch of at-bats this season — lowest in MLB.

Brewers hitters have an OPS of just .618 (462 PA’s) against LHP this season — 4th lowest in MLB.

Padres Pitching Stats & Trends

Opponents have a groundball rate of 48% against Padres pitchers this season — 3rd highest in MLB.

Opponents have a miss rate of 28% against Padres pitchers this season — tied for 3rd best in MLB.

Opponents have a Hard-Hit Avg of just 36% against the Padres pitchers this season — 2nd best in MLB.

Padres pitchers have a strikeout rate of 27% when facing the leadoff batter in the inning this season — best in MLB.

Brewers Pitching Stats & Trends

Brewers pitchers have a strikeout rate of 26% this season — best in MLB.

Opponents have a miss rate of 28% against Brewers pitchers this season — 5th best in MLB.

Brewers pitchers have a strikeout rate of 46% with two-strikes this season — 2nd best in MLB.

Brewers pitchers have a strikeout rate of 26% versus hitters not batting 3-4-5 in the order this season — 2nd best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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