• The Cubs are -125 favorites vs the Padres
• Padres vs Cubs Over / Under today: 12 Runs
• Padres / Cubs TV Channel: MARQ | PDTV

The San Diego Padres (+105) visit Wrigley Field to take on the Chicago Cubs (-125) on July 1, 2026. First pitch is scheduled for 2:20 pm in Chicago, IL.

This season, the Padres are 43-41 against the spread (ATS), while the Cubs are 35-50 ATS.

Padres vs Cubs Starting Pitchers Today:

• Padres starting pitcher: Walker Buehler 5-3, 3.86 ERA
• Cubs starting pitcher: Colin Rea 5-5, 4.81 ERA

Padres vs. Cubs Odds, Run Line, Over/Under & Moneyline

Padres vs Cubs Prediction for Today’s Game

Based on recent trends the model predicts the Cubs will win Wednesday‘s MLB game with 57.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Padres vs Cubs and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Padres players for Wednesday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Bets Today:

• Freddy Fermin has hit the Home Runs Over in 3 of his last 10 games (+26.00 Units / 260% ROI)
• Freddy Fermin has hit the Singles Under in 18 of his last 20 games (+15.15 Units / 49% ROI)
• Freddy Fermin has hit the Hits Runs and RBIs Under in 19 of his last 25 games (+13.65 Units / 45% ROI)
• Freddy Fermin has hit the Total Bases Under in 16 of his last 20 games (+13.20 Units / 59% ROI)
• Freddy Fermin has hit the Hits Under in 15 of his last 20 games (+11.15 Units / 52% ROI)

And here are some favorite MLB player prop bets for Cubs players for Wednesday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Best Bets Today:

• Pete Crow-Armstrong has hit the Home Runs Over in 6 of his last 9 games at home (+18.00 Units / 200% ROI)
• Nico Hoerner has hit the Hits Under in 19 of his last 25 games at home (+15.10 Units / 34% ROI)
• Michael Busch has hit the Runs Under in 20 of his last 25 games at home (+13.55 Units / 37% ROI)
• Michael Busch has hit the Walks Over in 18 of his last 25 games at home (+13.45 Units / 51% ROI)
• Pete Crow-Armstrong has hit the Hits Runs and RBIs Over in 13 of his last 15 games (+11.00 Units / 59% ROI)

Padres Best Bets Today:

• The San Diego Padres have hit the Game Total Under in 28 of their last 50 away games (+4.80 Units / 9% ROI)
• The San Diego Padres have hit the Team Total Over in 8 of their last 12 games (+3.95 Units / 28% ROI)
• The San Diego Padres have covered the Run Line in 7 of their last 10 games (+3.05 Units / 20% ROI)
• The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in 20 of their last 35 away games (+2.45 Units / 6% ROI)
• The San Diego Padres have hit the Moneyline in 23 of their last 45 away games (+1.85 Units / 4% ROI)

Cubs Best Bets Today:

• The Chicago Cubs have hit the Moneyline in 14 of their last 18 games (+9.40 Units / 39% ROI)
• The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 11 of their last 19 games (+8.50 Units / 32% ROI)
• The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Under in 27 of their last 45 games (+7.95 Units / 15% ROI)
• The Chicago Cubs have covered the Run Line in 8 of their last 12 games (+6.70 Units / 49% ROI)
• The Chicago Cubs have hit the Team Total Under in 13 of their last 19 games at home (+6.60 Units / 30% ROI)

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 44-38 against the Run Line (-0.35 Units / -0.31% ROI).

• 43-41 when betting on the Moneyline for -0.65 Units / -0.66% ROI
• 37-45 when betting on the total runs Over for -12.4 Units / -13.37% ROI
• 45-37 when betting on the total runs Under for +4.6 Units / 4.99% ROI

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 35-50 against the Run Line (-15.5 Units / -15.34% ROI).

• 48-38 when betting on the Moneyline for +0.05 Units / 0.04% ROI
• 46-39 when betting on the total runs Over for +3.65 Units / 3.85% ROI
• 39-46 when betting on the total runs Under for -11 Units / -11.64% ROI

Cubs vs Padres Home Run Prop Bets Today

Cubs vs Padres Total Hits Prop Bets Today

Cubs vs Padres Strikeout Prop Bets Today

Padres Keys to the Game vs. the Cubs

The Padres are 9-4 (.692) when tied entering the 7th inning this season — 4th best in MLB; League Avg: .500.

The Padres are 32-1 (.970) when leading entering the 8th inning this season — 5th best in MLB; League Avg: .898.

The Padres are 33-0 (1.000) when leading entering the 9th inning this season — tied for best in MLB; League Avg: .944.

The Padres are 4-38 (.095) when trailing entering the 9th inning this season — 4th best in MLB; League Avg: .056.

Cubs Keys to the Game vs. the Padres

The Cubs are 30-17 (.638) after a win this season — 3rd best in MLB; League Avg: .517.

The Cubs are 6-28 (.176) when trailing entering the 7th inning this season — 5th best in MLB; League Avg: .140.

The Cubs are 4-36 (.100) when trailing entering the 9th inning this season — 3rd best in MLB; League Avg: .056.

The Cubs are 19-1 (.950) when they’ve had 5 or more XBH this season — 2nd best in MLB; League Avg: .786.

Padres Hitting Stats & Trends

Padres hitters have an OPS of just .669 (3,083 PA’s) this season — lowest in MLB.

Padres hitters are slugging just .350 against starting pitchers this season — lowest in MLB.

Padres hitters have an OPS of just .651 (1,581 PA’s) at home this season — lowest in MLB.

Padres hitters have an OPS of just .634 (1,785 PA’s) against starting pitchers this season — lowest in MLB.

Cubs Hitting Stats & Trends

Cubs hitters have an OBP of .350 (959 PA’s) against LHP this season — best in MLB.

Cubs hitters have come to the plate with runners in scoring position in 989 of their 3,398 plate appearances (29%) this season — 2nd highest in MLB.

Cubs hitters have an OBP of .353 (1,653 PA’s) at home this season — 2nd best in MLB.

Cubs hitters have drawn walks in 12% of their PA’s when leading off an inning this season — best in MLB.

Padres Pitching Stats & Trends

Padres pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — 4th highest in MLB.

Opponents have a groundball rate of 45% against Padres pitchers this season — 5th highest in MLB.

The Padres have allowed 1.04 runs per game (87/84) in late innings this season — 3rd best in MLB.

Padres pitchers have allowed an exit velocity over 105 MPH 166 times this season — tied for 5th fewest in MLB.

Cubs Pitching Stats & Trends

Opponents have a groundball batting average of just .199 against Cubs pitchers with runners on base this season — best in MLB.

Cubs pitchers have picked-off 15 runners from first base this season — most in MLB.

Opponents have a groundball batting average of just .223 against Cubs pitchers this season — 3rd best in MLB.

Cubs pitchers have allowed an exit velocity over 105 MPH 227 times this season — 5th most in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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