• The Orioles are -145 favorites vs the Padres
• Padres vs Orioles Over / Under today: 9 Runs
• Padres / Orioles TV Channel: MASN | PDTV

The San Diego Padres (+118) visit Oriole Park at Camden Yards to take on the Baltimore Orioles (-145) on June 12, 2026. First pitch is scheduled for 7:05 pm in Baltimore, MD.

This season, the Padres are against the spread (ATS), while the Orioles are ATS.

Padres vs Orioles Starting Pitchers Today:

• Padres starting pitcher: Griffin Canning 0-4, 6.41 ERA
• Orioles starting pitcher: Shane Baz 3-6, 4.01 ERA

Padres vs. Orioles Odds, Run Line, Over/Under & Moneyline

Padres vs Orioles Prediction for Today’s Game

Based on recent trends the model predicts the Orioles will win Friday‘s MLB game with 57.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Padres vs Orioles and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Padres players for Friday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Bets Today:

• Jackson Merrill has hit the Singles Under in 19 of his last 25 away games (+13.15 Units / 45% ROI)
• Fernando Tatis Jr. has hit the Hits Over in 16 of his last 20 games (+10.90 Units / 29% ROI)
• Jackson Merrill has hit the Home Runs Over in 2 of his last 6 away games (+7.80 Units / 130% ROI)
• Jackson Merrill has hit the Hits Runs and RBIs Under in 17 of his last 25 away games (+7.50 Units / 24% ROI)
• Fernando Tatis Jr. has hit the Walks Under in 12 of his last 15 games (+7.40 Units / 28% ROI)

And here are some favorite MLB player prop bets for Orioles players for Friday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Best Bets Today:

• Colton Cowser has hit the Home Runs Over in 4 of his last 9 games (+20.60 Units / 229% ROI)
• Manny Machado has hit the Singles Under in 20 of his last 25 games (+13.05 Units / 38% ROI)
• Adley Rutschman has hit the Walks Over in 8 of his last 9 games at home (+12.15 Units / 135% ROI)
• Gunnar Henderson has hit the Hits Under in 15 of his last 25 games at home (+10.15 Units / 31% ROI)
• Gunnar Henderson has hit the RBIs Under in his last 10 games (+10.00 Units / 44% ROI)

Padres Best Bets Today:

• The San Diego Padres have hit the Team Total Under in 32 of their last 50 games (+11.90 Units / 20% ROI)
• The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in 16 of their last 25 away games (+5.65 Units / 18% ROI)
• The San Diego Padres have hit the Game Total Under in 21 of their last 35 games (+5.65 Units / 15% ROI)
• The San Diego Padres have hit the Moneyline in 22 of their last 40 away games (+3.85 Units / 8% ROI)
• The San Diego Padres have covered the Run Line in 11 of their last 18 away games (+3.60 Units / 15% ROI)

Orioles Best Bets Today:

• The Baltimore Orioles have covered the Run Line in 18 of their last 30 games at home (+9.85 Units / 27% ROI)
• The Baltimore Orioles have hit the Team Total Over in 15 of their last 20 games (+9.45 Units / 38% ROI)
• The Baltimore Orioles have hit the Game Total Over in 29 of their last 50 games (+9.25 Units / 17% ROI)
• The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Under in 30 of their last 50 games at home (+7.55 Units / 12% ROI)
• The Baltimore Orioles have hit the Moneyline in 12 of their last 18 games at home (+6.05 Units / 30% ROI)

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are against the Run Line ( Units / ROI).

• away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• away total over record when betting on the total runs Over for over units Units / over ROI ROI
• away total under record when betting on the total runs Under for under units Units / under ROI ROI

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are against the Run Line ( Units / ROI).

• home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• home total over record when betting on the total runs Over for over units Units / over ROI ROI
• home total under record when betting on the total runs Under for under units Units / under ROI ROI

Orioles vs Padres Home Run Prop Bets Today

Orioles vs Padres Total Hits Prop Bets Today

Orioles vs Padres Strikeout Prop Bets Today

Padres Keys to the Game vs. the Orioles

The Padres are 4-30 (.118) when trailing entering the 9th inning this season — tied for 2nd best in MLB; League Avg: .057.

The Padres are 26-1 (.963) when leading entering the 8th inning this season — 5th best in MLB; League Avg: .890.

The Padres are 21-1 (.955) when scoring 5 or more runs this season — best in MLB; League Avg: .792.

The Padres are 8-3 (.727) when tied entering the 7th inning this season — 3rd best in MLB; League Avg: .500.

Orioles Keys to the Game vs. the Padres

The Orioles are just 6-30 (.167) when scoring 4 or fewer runs this season — 2nd lowest in MLB; League Avg: .274.

The Orioles are 10-3 (.769) when they’ve scored in the first inning this season — 5th best in MLB; League Avg: .645.

The Orioles are just 6-11 (.353) when tied entering the 8th inning since the 2025 season — 4th lowest in MLB; League Avg: .500.

The Orioles are just 11-15 (.423) when tied entering the 7th inning since the 2025 season — 5th lowest in MLB; League Avg: .500.

Padres Hitting Stats & Trends

Padres hitters have an OPS of just .651 (2,438 PA’s) this season — lowest in MLB.

Padres hitters have an OBP of just .291 (2,438 PA’s) this season — tied for lowest in MLB.

Padres hitters have an OBP of just .293 (1,081 PA’s) on the road this season — 3rd lowest in MLB.

Padres hitters have an OPS of just .607 (1,451 PA’s) with bases empty this season — lowest in MLB.

Orioles Hitting Stats & Trends

The Orioles are batting just .133 on pitches out of the zone this season — 3rd lowest in MLB.

The Orioles are batting just .154 with two-strikes this season — 3rd lowest in MLB.

Orioles hitters are slugging just .175 on pitches out of the zone this season — 3rd lowest in MLB.

The Orioles have an average Exit Velocity of 90.1 MPH this season — best in MLB.

Padres Pitching Stats & Trends

Opponents have a groundball rate of 46% against Padres pitchers this season — tied for 2nd highest in MLB.

Padres pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — tied for 3rd highest in MLB.

Padres pitchers have allowed an exit velocity over 100 MPH 346 times this season — 3rd fewest in MLB.

Opponents have a groundball batting average of .261 against Padres pitchers this season — 5th highest in MLB.

Orioles Pitching Stats & Trends

The Orioles have allowed 5.75 runs per game (184/32) on the road this season — 2nd highest in MLB.

Orioles pitchers have an ERA of 5.52 (272.1 IP) on the road this season — 2nd highest in MLB.

Opponents are hitting .261 against Orioles pitchers this season — 2nd highest in MLB.

Orioles pitchers have a strikeout rate of just 20% this season — 5th lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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