Reds vs Blue Jays Prediction, Odds & Player Prop Bets Today – MLB, Sep 25

Toronto Blue Jays' Vladimir Guerrero Jr. plays against the Boston Red Sox during the fourth inning of a baseball game, Thursday, May 4, 2023, in Boston.
(AP Photo/Michael Dwyer)
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  • The Blue Jays are -140 favorites vs the Reds
  • Reds vs Blue Jays Over / Under today: 7.5 Runs
  • Reds / Blue Jays TV Channel: RDTV | RSN | TVA

The Cincinnati Reds (+115) visit Rogers Centre to take on the Toronto Blue Jays (-140) on September 25, 2026. First pitch is scheduled for 7:07 pm in Toronto, ON.

This season, the Reds are 74-85 against the spread (ATS), while the Blue Jays are 78-80 ATS.

Reds vs Blue Jays Starting Pitchers Today:

  • Reds starting pitcher: Nick Lodolo 3-6, 5.04 ERA
  • Blue Jays starting pitcher: Undecided 0-0, 0.00 ERA

Reds vs. Blue Jays Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Reds+1.5 -200O 7.5 -102+115
Blue Jays -1.5 +165U 7.5 -118-140

Reds vs Blue Jays Prediction for Today’s Game

Based on recent trends the model predicts the Blue Jays will win Friday‘s MLB game with 57.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Reds players for Friday‘s game, looking at profitable historical betting trends:

Best Reds Player Prop Bets Today:

  • Elly De La Cruz has hit the Home Runs Over in 5 of his last 9 away games (+18.30 Units / 203% ROI)
  • JJ Bleday has hit the Hits Runs and RBIs Under in 20 of his last 25 away games (+13.95 Units / 42% ROI)
  • Elly De La Cruz has hit the Total Bases Over in 15 of his last 20 games (+11.95 Units / 51% ROI)
  • Sal Stewart has hit the Singles Over in 19 of his last 25 away games (+11.90 Units / 41% ROI)
  • Elly De La Cruz has hit the Runs Over in 17 of his last 25 games (+11.60 Units / 45% ROI)

And here are some favorite MLB player prop bets for Blue Jays players for Friday‘s game, looking at profitable historical betting trends:

Best Blue Jays Player Prop Best Bets Today:

  • Brett Bateman has hit the Home Runs Over in 2 of his last 6 games at home (+19.00 Units / 317% ROI)
  • Alejandro Kirk has hit the Singles Over in 22 of his last 25 games (+18.00 Units / 54% ROI)
  • Ernie Clement has hit the Total Bases Under in 18 of his last 20 games at home (+16.00 Units / 45% ROI)
  • Alejandro Kirk has hit the Hits Over in 21 of his last 25 games at home (+12.50 Units / 24% ROI)
  • Brett Bateman has hit the Runs Over in his last 9 games at home (+10.60 Units / 118% ROI)
  • The Cincinnati Reds have hit the 1st Five Innings (F5) Team Total Under in 28 of their last 45 games (+8.35 Units / 15% ROI)
  • The Cincinnati Reds have hit the Game Total Over in 9 of their last 13 away games (+4.70 Units / 33% ROI)
  • The Cincinnati Reds have hit the Moneyline in 3 of their last 5 away games (+3.55 Units / 71% ROI)
  • The Cincinnati Reds have hit the Team Total Over in 4 of their last 5 away games (+3.15 Units / 57% ROI)
  • The Cincinnati Reds have covered the Run Line in 4 of their last 5 away games (+2.85 Units / 50% ROI)
  • The Toronto Blue Jays have hit the 1st Five Innings (F5) Team Total Under in 24 of their last 35 games at home (+11.55 Units / 27% ROI)
  • The Toronto Blue Jays have covered the Run Line in 15 of their last 23 games at home (+9.40 Units / 35% ROI)
  • The Toronto Blue Jays have hit the Team Total Over in 8 of their last 9 games at home (+7.25 Units / 67% ROI)
  • The Toronto Blue Jays have hit the Moneyline in 15 of their last 23 games at home (+6.55 Units / 22% ROI)
  • The Toronto Blue Jays have hit the Game Total Over in 25 of their last 45 games (+4.25 Units / 9% ROI)

Reds Against the Spread (ATS) Record

Against the spread this season, the Reds are 81-76 against the Run Line (-13.9 Units / -6.41% ROI).

  • 74-85 when betting on the Moneyline for -5.15 Units / -2.93% ROI
  • 83-72 when betting on the total runs Over for +3.6 Units / 2.05% ROI
  • 72-83 when betting on the total runs Under for -18.9 Units / -10.84% ROI

Blue Jays Against the Spread (ATS) Record

Against the spread this season, the Blue Jays are 78-80 against the Run Line (-8.8 Units / -4.31% ROI).

  • 77-82 when betting on the Moneyline for -15.5 Units / -7.89% ROI
  • 80-75 when betting on the total runs Over for -2.1 Units / -1.2% ROI
  • 75-80 when betting on the total runs Under for -12.85 Units / -7.33% ROI

Reds Keys to the Game vs. the Blue Jays

The Reds are 7-76 (.084) when trailing entering the 9th inning this season — 3rd best in MLB.

The Reds are just 30-43 (.411) after a win this season — 5th lowest in MLB.

The Reds are just 8-18 (.308) when tied entering the 7th inning this season — 4th lowest in MLB.

The Reds are just 23-41 (.359) when tied entering the 8th inning since the 2024 season — lowest in MLB.

Blue Jays Keys to the Game vs. the Reds

The Blue Jays are just 7-57 (.109) when allowing 5 or more runs this season — 2nd lowest in MLB.

The Blue Jays are just 13-38 (.255) when their opponents score in the first inning this season — lowest in MLB.

The Blue Jays are just 7-66 (.096) when trailing entering the 7th inning this season — tied for 4th lowest in MLB.

The Blue Jays were 12-53 (.185) when trailing entering the 8th inning in the 2025 season — best in MLB; League Avg: .090.

Reds hitters have struck out in 26% of their PA’s against RHP this season — 2nd highest in MLB.

Reds hitters have struck out in 25% of their PA’s against LHP this season — tied for 2nd highest in MLB.

The Reds are batting just .208 with two outs this season — lowest in MLB.

The Reds are batting just .225 when facing the starting pitcher for the 3rd time in a game this season — lowest in MLB.

The Blue Jays are batting .196 with two-strikes this season — best in MLB.

Blue Jays hitters have an OPS of just .952 (1,116 PA’s) with the pitcher behind in the count this season — lowest in MLB.

Blue Jays hitters are slugging just .488 in non-two strike counts this season — lowest in MLB.

Blue Jays hitters have struck out in just 19% of their PA’s against RHP this season — best in MLB.

Reds pitchers have walked 10% of batters this season — 2nd highest in MLB.

Reds pitchers have allowed an average Exit Velocity of 89.6 MPH (4,041 batted balls) this season — 2nd highest in MLB.

The Reds pitchers have allowed their opponents to score first in 62% of their games this season — highest in MLB.

The Reds pitchers have allowed an average Exit Velocity of 89.6 MPH this season (4,041 balls in play) — 2nd highest in MLB

The Blue Jays pitchers have allowed an average Exit Velocity of just 87.6 MPH this season (3,912 balls in play) — best in MLB

Blue Jays pitchers have walked 10% of batters this season — 5th highest in MLB.

Blue Jays pitchers have allowed an average Exit Velocity of 87.6 MPH (3,912 batted balls) this season — best in MLB.

The Blue Jays pitchers have allowed their opponents to score first in 58% of their games this season — 3rd highest in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.