From 2003-14 the Indianapolis Colts dominated the AFC South, winning eight of 12 division titles. The Colts haven’t won the division since but will look to snap the seven-year drought this season.
They didn’t open atop NFL odds to win the AFC South but became the favorite – of the oddsmakers and public – over the course of the offseason.
Here are updated 2022 AFC South odds and public betting insights (as of Sept. 27):
| Team | Open | Week 3 | Current | Tickets | Handle |
|---|---|---|---|---|---|
| Colts | +140 | +125 | +105 | 37% | 58.7% |
| Jaguars | +550 | +300 | +220 | 29% | 20.2% |
| Titans | +100 | +200 | +280 | 23.6% | 16.6% |
| Texans | +2500 | +1600 | +3300 | 10.5% | 4.5% |
NFL Betting Odds at BetMGM
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