Saints vs Giants Prediction, Odds & Best Prop Bets โ€“ NFL, Week 6

A general overall interior view of MetLife Stadium as the New York Giants take on the Carolina Panthers during the first half an NFL football game, Sunday, Sept. 18, 2022, in East Rutherford, N.J. (AP Photo/Seth Wenig)
(AP Photo/Seth Wenig)
Boost Pack This Weekend
  • The Saints are +1.5 point favorites vs the Giants
  • Total (Over/Under): 45.5 points
  • Watch this game on FOX

The New Orleans Saints (1-4-0) visit MetLife Stadium to take on the New York Giants (3-1-1) on Oct. 18. Kickoff is scheduled for 1:00 pm in East Rutherford, NJ.

The Saints are betting favorites in this matchup, with the spread sitting at +1.5 (-135).

The Saints vs. Giants Over/Under is 45.5 total points for the game.

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Saints vs. Giants Odds, Spread, Over/Under

SpreadTotal (O/U)Moneyline
Saints+1.5 -13545.5 -108-115
Giants -1.5 +10045.5 -110-102

Saints vs. Giants Prediction

The winning team model predicts the Giants will win this game with 53.3% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Saints vs Giants Spread Prediction

Based on recent against-the-spread trends, the model predicts the Giants will cover the spread with 53.4% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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We’ve highlighted some favorite NFL player prop bets for Saints players this game, looking at profitable historical betting trends:

Best Saints Player Prop Bets Today

  • Daniel Carlson has hit the Field Goals Under in 11 of his last 14 games (+7.85 Units / 45% ROI)
  • Tyler Shough has hit the Passing Yards Over in 11 of his last 14 games (+7.55 Units / 47% ROI)
  • Tyler Shough has hit the Completions Over in 11 of his last 14 games (+7.50 Units / 46% ROI)
  • Chris Olave has hit the Receiving Yards Over in 11 of his last 15 games (+6.35 Units / 37% ROI)
  • Juwan Johnson has hit the Receptions Over in 11 of his last 16 games (+6.35 Units / 34% ROI)

And here are some top NFL player prop bets for Giants players for this matchup, looking at profitable historical betting trends:

Best Giants Player Prop Best Bets Today

  • Theo Johnson has hit the Receptions Under in 11 of his last 13 games (+9.50 Units / 58% ROI)
  • J.J. McCarthy has hit the Completions Under in his last 6 games (+6.00 Units / 86% ROI)
  • J.J. McCarthy has hit the Pass Attempts Under in his last 5 games (+5.00 Units / 88% ROI)
  • Tyrone Tracy Jr. has hit the Rushing Yards Over in 9 of his last 13 games (+4.57 Units / 30% ROI)
  • J.J. McCarthy has hit the Passing Yards Under in 5 of his last 6 games (+3.85 Units / 57% ROI)

First Touchdown Scorer Bet for Giants vs Saints

Player Name 1st TD Odds
Cam Skattebo +500
Kendre Miller +825
Chris Olave +850
Malik Nabers +900
Alvin Kamara +950

Anytime Touchdown Scorer Bet for Giants vs Saints

Player Name Anytime TD Odds
Cam Skattebo -111
Chris Olave +145
Kendre Miller +150
Alvin Kamara +150
Malik Nabers +165

Receiving Props: Total Receiving Yards for Giants vs Saints

Player Name Over Under
Chris Olave 77.5 -115 77.5 -115
Malik Nabers 69.5 -115 69.5 -115
Isaiah Likely 48.5 -115 48.5 -115
Devaughn Vele 45.5 -115 45.5 -115
Juwan Johnson 39.5 -115 39.5 -115

Rushing Props: Total Rushing Yards for Giants vs Saints

Player Name Over Under
Cam Skattebo 56.5 -115 56.5 -115
  • The New Orleans Saints have hit the 2H Moneyline in 8 of their last 9 away games (+10.78 Units / 117% ROI)
  • The New Orleans Saints have hit the 4Q Moneyline in 7 of their last 9 away games (+7.55 Units / 82% ROI)
  • The New Orleans Saints have covered the 3Q Spread in 8 of their last 9 away games (+7.10 Units / 64% ROI)
  • The New Orleans Saints have covered the 2H Spread in 8 of their last 9 away games (+7.00 Units / 69% ROI)
  • The New Orleans Saints have hit the 1H Team Total Under in 12 of their last 17 games (+6.75 Units / 36% ROI)
  • The New York Giants have covered the 3Q Spread in 14 of their last 16 games (+12.20 Units / 61% ROI)
  • The New York Giants have hit the 1H Moneyline in 11 of their last 19 games (+8.55 Units / 39% ROI)
  • The New York Giants have hit the 3Q Moneyline in 8 of their last 16 games (+6.85 Units / 40% ROI)
  • The New York Giants have hit the Team Total Over in 12 of their last 18 games (+5.35 Units / 26% ROI)
  • The New York Giants have hit the 1H Team Total Over in 11 of their last 17 games (+4.35 Units / 22% ROI)

Saints Against the Spread (ATS) Record

Against the spread this NFL season, the Saints are 2-3 (-1.3 Units / -23.64% ROI).

  • Saints are 1-4 when betting on the Moneyline for -1.85 Units / -30.33% ROI
  • Saints are 3-2 when betting the Over for +0.8 Units / 14.55% ROI
  • SaintsSaintsSaints are 2-3 when betting the Under for -1.3 Units / -23.64% ROI

Giants Against the Spread (ATS) Record

Against the spread this NFL season, the Giants are 4-1 (+2.9 Units / 52.73% ROI).

  • Giants are 3-1 when betting on the Moneyline for +2.65 Units / 49.07% ROI
  • Giants are 3-2 when betting the Over for +0.8 Units / 14.55% ROI
  • Giants are 2-3 when betting the Under for -1.3 Units / -23.64% ROI

New Orleans Saints: Keys to the Game vs. the New York Giants

The Saints are 2-11 (.154) when making less than 5 explosive passes in a game since the 2025 season — 2nd-worst in NFL; League Avg: .444.

The Saints are winless (0-5) when allowing more than 5 yards per rush since the 2025 season — worst in NFL; League Avg: .411.

The Saints are 2-10 (.167) when intercepting no passes since the 2025 season — 9th-worst in NFL; League Avg: .338.

The Saints are 2-11 (.154) when losing at least one fumble since the 2025 season — 5th-worst in NFL; League Avg: .360.

New York Giants: Keys to the Game vs. the New Orleans Saints

The Giants are 1-9-1 (.091) on the road since the 2025 season — worst in NFL; League Avg: .460.

The Giants are 1-10-1 (.083) when allowing 5 or more explosive passes since the 2025 season — 3rd-worst in NFL; League Avg: .430.

The Giants are 3-12-1 (.188) when making less than 3 explosive runs in a game since the 2025 season — 4th-worst in NFL; League Avg: .415.

The Giants are winless (0-12-1) when trailing at the end of the third quarter since the 2025 season — T-worst in NFL; League Avg: .161.

Additional Matchup Notes for New Orleans Saints vs. New York Giants

The Giants have run 55.1% offensive plays on their opponent’s side of the field this season — 2nd-best in NFL. The Saints have allowed their opponents to run 56.0% of plays in their territory this season — 2nd-worst in NFL.

Giants TEs have averaged 11.4 targets per game this season — 3rd-highest in NFL. The Saints have allowed 7.2 receptions per game to TEs this season — T-4th-highest in NFL.

The Giants have averaged 0.51 epa per play with a light rush since the 2025 season — 4th-best in NFL. The Saints have allowed 0.60 epa per play with a light rush since the 2025 season — 3rd-worst in NFL.

Saints RBs have averaged 8.0 targets per game this season — 2nd-highest in NFL. The Giants have allowed just 3.4 receptions per game to RBs this season — T-4th-lowest in NFL.

The Saints have a third down conversion rate of 45.7% in the second half this season — 5th-best in NFL. The Giants defense has allowed a third down conversion rate of 56.0% in the second half this season — 2nd-worst in NFL.

The Saints have gone three and out on 36% of their drives in the first half this season — T-5th-worst in NFL. The Giants have forced three and outs on 40.6% of opponent drives in the first half this season — best in NFL.

New Orleans Saints Offense: Important Stats

The Saints have gone three and out 23 times in the 1st quarter since the 2025 season — most in NFL.

The Saints have scored on 13% of their drives (8/60) in the 1st quarter since the 2025 season — worst in NFL; League Avg: 32%.

The Saints have converted late downs on 22 of 87 plays (25%) in short yardage situations this season — best in NFL; League Avg: 17%.

The Saints have gone three and out on 38% of their drives in the 1st quarter since the 2025 season — worst in NFL; League Avg: 21%.

New York Giants Offense: Important Stats

The Giants have turned the ball over on downs 10 times in the red zone since the 2025 season — most in NFL.

The Giants have run successful plays on 26% of rush attempts against a stacked front since the 2025 season — worst in NFL; League Avg: 46%.

The Giants ran 83 plays in Week 5 — most in NFL.

The Giants have run successful plays on 37% of plays in the 1st quarter since the 2025 season — 2nd-worst in NFL; League Avg: 44%.

New Orleans Saints Defense: Important Stats

The Saints defense has allowed successful plays on 31% of pass attempts in the 4th quarter since the 2025 season — best in NFL; League Avg: 45%.

The Saints defense has allowed a third down conversion rate of 46% with tight coverage this season — worst in NFL; League Avg: 19%.

The Saints defense forced 4 fumbles in Week 5 — T-most in NFL.

The Saints defense allowed successful plays on 80% of plays first read passes in Week 5 — worst in NFL; League Avg: 49%.

New York Giants Defense: Important Stats

The Giants defense allowed successful plays on 83% of plays in the 3rd quarter in Week 5 — worst in NFL; League Avg: 44%.

Offenses facing the Giants targeted RBs 11% of the time (17 Pass Attempts/161 plays) this season — lowest in NFL; League Avg: 17%.

The Giants defense has allowed successful plays on 59% of rush attempts in the 1st quarter this season — worst in NFL; League Avg: 42%.

The Giants defense has allowed first downs on just 3% of plays on plays when they have pressured the QB this season — best in NFL; League Avg: 17%.

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.