Southampton vs. Manchester United Prediction, Odds & Preview

  • Southampton is predicted to be a +0.5-goal underdog against Manchester United.
  • Manchester United has won 13 of their last 14 against promoted teams.
  • I predict Manchester United earn all three points at St. Maryโ€™s Stadium.

Seeking an end to their two-match losing streak, Manchester United travel to face Southampton.ย 

Prior to the international break, the Red Devils lost 3-0 at home to Liverpool, their second straight defeat following a road loss to Brighton.ย 

Southampton has yet to earn points this season. In their last match, they traveled to Brentford and received a 3-1 thumping.ย 

Hereโ€™s a look at the Premier League odds and my prediction for this fixture.ย 

Southampton vs. Manchester United Odds, Premier League

  • Southampton Moneyline: +333
  • Manchester United Moneyline: -135
  • Draw Moneyline: +290
  • Over/Under: 2.5 Goals (-160/+115)
  • Both Teams to Score: Yes (-160), No (+110)

Southampton vs. Manchester United Prediction: Moneyline

My prediction for Saturdayโ€™s Southampton vs. Manchester United fixture is the Manchester United Moneyline (-135).ย 

I hate that I have to make this bet. I canโ€™t even remember the last time I put real dollars on Manchester United.ย 

But thereโ€™s evidence supporting a bet on the Red Devils, who have won 13 of their last 14 against promoted teams.ย 

United has lost two straight, yes, but they thoroughly dominated the opening match against Fulham.ย 

Erik ten Hagโ€™s squad only won the match 1-0. However, expected goals finished 2.4 to 0.4 in favor of the hosts.ย 

Even if you discount the Alejandro Garnacho attempt worth 0.67 xG and zero psxG in the 94th minute, United won the psxG battle 2.1 to 0.9, per fbref.com.ย 

Plus, Southampton has actually run lucky in their last two matches. The Saints posted a -3 goal differential compared to a -4.1 psxGDiff against Nottingham Forest and Brentford.ย 

Two systems also suggest United is worth a bet.ย 

First, early moneyline moves on favorites tend to signal the correct side. Since 2012, favorites in games 1-9 that see their moneyline rise are 67.5% SU, assuming two factors:

  • The previous head-to-head result was either +0 or +1
  • The underdogโ€™s previous game margin fell between -8 and -1

When those favorites are coming off a loss, theyโ€™re 19-5 SU (79.2%), including 11-2 SU (84.6%) off a multi-goal defeat.ย 

The other system suggests fading previous dogs early.ย 

Since 2012, favorites priced between -205 and -105 in games 2-10 are 78% SU, assuming three factors:

  • The underdogโ€™s previous game margin fell between -4 and +0
  • The underdog was an underdog in their previous game
  • The previous head-to-head result fell between +0 and +4

When those favorites are playing off a loss, theyโ€™re 24-7 SU and have dropped all three points only four times.ย 

Based on those outlays, lay the juice with United off an extended rest period.ย 

Southampton Record, Last 5 Matches

  • Aug. 31 at Brentford: 1-3, L
  • Aug. 28 at Cardiff City: 5-3, W (EFL Cup)
  • Aug. 24 vs. Nottingham Forest: 0-1, L
  • Aug. 17 at Newcastle United: 0-1, L
  • Aug. 10 vs. Getafe: 0-0, D (Friendly)

Manchester United Record, Last 5 Matches

  • Sept. 1 vs. Liverpool: 0-3, L
  • Aug. 24 at Brighton: 1-2, L
  • Aug. 16 vs. Fulham: 1-0, W
  • Aug. 10 vs. Man City: 1-1, D (City Win on PKโ€™s)
  • Aug. 3 vs. Liverpool: 0-3, L (Friendly)

Visit the BetMGM online sportsbook for the latest Southampton odds and Manchester United odds!

EPL Match Schedule This Weekend

HomeAwayDateTime (ET)Location
ChelseaEvertonApr. 267:30 a.m.Stamford Bridge
SouthamptonFulhamApr. 2610 a.m.St. Mary's Stadium
BrightonWest Ham UnitedApr. 2610 a.m.Amex Stadium
Newcastle UnitedIpswich TownApr. 2610 a.m.St. James' Park
WolvesLeicester CityApr. 2610 a.m.Molinneux
BournemouthManchester UnitedApr. 279 a.m.Vitality Stadium
LiverpoolTottenhamApr. 2711:30 a.m.Anfield

EPL Standings

TeamRecord (Wins-Draws-Losses)PointsGoal Differential
Liverpool25-7-28248
Arsenal18-13-36834
Newcastle United19-5-106221
Manchester City18-7-96123
Chelsea17-9-86019
Nottingham Forest18-6-96014
Aston Villa16-9-9575
Fulham14-9-11514
Brighton13-13-8511
Bournemouth13-11-105012
Brentford13-7-13466
Crystal Palace11-12-1145-4
Wolves12-5-1741-10
Manchester United10-9-1539-8
Everton8-14-1238-7
Tottenham11-4-19376
West Ham9-9-1636-19
Ipswich Town4-9-2121-41
Leicester City4-6-2418-49
Southampton2-5-2711-55

EPL ATS Records

TeamATS RecordATS%Home ATS RecordHome ATS%Road ATS RecordRoad ATS%
Arsenal12-16-644.1%4-9-435.3%8-7-252.9%
Aston Villa15-18-145.6%7-9-144.1%8-9-047.1%
Bournemouth18-14-255.9%8-9-047.1%10-5-264.7%
Brentford20-11-263.6%10-7-058.8%10-4-268.8%
Brighton & Hove Albion18-15-154.4%8-9-047.1%10-6-161.8%
Chelsea12-19-339.7%6-9-241.2%6-10-138.2%
Crystal Palace18-12-458.8%7-6-452.9%11-6-064.7%
Everton17-11-658.8%8-7-252.9%9-4-464.7%
Fulham18-12-458.8%8-9-047.1%9-4-464.7%
Ipswich Town13-19-241.2%4-13-023.5%9-6-258.8%
Leicester City15-18-145.6%6-11-035.3%9-7-155.9%
Liverpool16-16-250.0%7-8-247.1%9-8-052.9%
Manchester City12-22-035.3%6-11-035.3%6-11-035.3%
Manchester United14-16-447.1%7-8-247.1%7-8-247.1%
Newcastle United20-13-160.3%12-5-070.6%8-8-150.0%
Nottingham Forest21-12-063.6%10-6-062.5%11-6-064.7%
Southampton12-18-441.2%3-12-223.5%9-6-258.8%
Tottenham Hotspur12-21-136.8%6-10-138.2%6-11-035.3%
West Ham United17-15-252.9%6-10-138.2%11-6-064.7%
Wolverhampton Wanderers18-13-357.4%8-7-252.9%10-6-161.8%
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About the Author

Nick Hennion

Read More @nickhennion

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.