The Patriots (5-4) visit the Lions (6-2) in Week 10 on Nov. 15, 2026, at the Allianz Arena in Munich, Germany. Kickoff is set for 9:30 a.m. ET (6:30 a.m. PT), with the game airing on FOX.
Below, bettors can find NFL odds and a Lions vs Patriots prediction for this matchup.
Lions vs Patriots Odds: Spread, Moneyline & Total
Patriots vs Lions Prediction
Based on Detroit’s defensive injuries and the Patriots’ ability to pass on opposing defenses, my Lions vs Patriots prediction is the Patriots Spread (+3, -118).
No outcome would surprise me in this game. Accordingly, confidence in this prediction is relatively low, but the worst unit on the field is the Lions defense.
Detroit is back to less-than-perfect health on defense. While the unit looked good against Miami, the Patriots qualify as a step up in competition.
If Drake Maye gets back A.J. Brown, it could put Detroit’s corners in trouble. That’s where they’ve played worse anyway, as the Lions rank 24th in pass defense DVOA.
New England struggled to move the ball on Green Bay. However, it’s a step down in competition as the Packers rank a top-five pass defense by DVOA.
Detroit’s defense is essentially Aidan Hutchinson and a bunch of other dudes. Additionally, the Patriots offense hasn’t so much been bad as it has turned the ball over a bunch.
On plays excluding turnovers, New England ranks fourth in both EPA per play and dropback EPA per play. Conversely, the Lions rank 27th and 25th in the corresponding defensive categories.
My concern is how New England’s defense holds up. A unit I once trusted surrendered 45 points to a good Packers offense. Detroit could, in theory, achieve the same.
While the Lions have scored under 20.5 points in three straight, the output is a tad misleading. Against Green Bay, Minnesota and Miami, the Lions finished 4-for-12 in the red zone.
Green Bay finished 4-for-5 in the red zone against New England. It could inform some positive regression by Detroit’s offense.
If that happens, Detroit could easily cover this number. However, I like New England’s offense enough that I could see the Patriots keeping the game respectable.
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