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The Trojans odds to win the Big Ten are +5000.
The Trojans national championship odds are +8000.
The Trojans odds to make the College Football Playoff are +625.
Northwestern (5-3) visit Los Angeles Memorial Coliseum to take on USC (6-2) on Nov. 7 in Los Angeles, CA. Kickoff is scheduled for 9:00pm EST. USC is a betting favorite in Week 11, with the spread sit Read More
USC (5-2) visit Memorial Stadium (Lincoln, NE) to take on Nebraska (6-2) on Nov. 1 in Lincoln, NE. Kickoff is scheduled for 7:30pm EDT. USC is a betting favorite in Week 10, with the spread sitting at Read More
USC (5-1) visit Notre Dame Stadium to take on Notre Dame (4-2) on Oct. 18 in South Bend, IN. Kickoff is scheduled for 7:30pm EDT. Notre Dame is a betting favorite in Week 8, with the spread sitting at Read More
Here’s a college football betting preview for USC vs. Notre Dame, including the current BetMGM odds and a betting prediction. Read More
Michigan (4-1) visit Los Angeles Memorial Coliseum to take on USC (4-1) on Oct. 11 in Los Angeles, CA. Kickoff is scheduled for 7:30pm EDT. USC is a betting favorite in Week 7, with the spread sitting Read More
Here are Chase Kiddy’s best college football bets and predictions for Week 7 of the 2025 season. Read More
USC (4-0) visit Memorial Stadium (Champaign, IL) to take on Illinois (3-1) on Sep. 27 in Champaign, IL. Kickoff is scheduled for 12:00pm EDT. USC is a betting favorite in Week 5, with the spread sitti Read More
Michigan State (3-0) visit Los Angeles Memorial Coliseum to take on USC (3-0) on Sep. 20 in Los Angeles, CA. Kickoff is scheduled for 11:00pm EDT. USC is a betting favorite in Week 4, with the spread Read More
These are the highest-scoring USC football games of all time. Read More
College football odds are available throughout the season, including odds for each Big Ten team:
Spreads, over/under totals, moneylines, and more odds are available for each USC football game this season.
Will the Trojans make the College Football Playoff? Will they go over or under their regular-season win total? Will they win the national championship?
For example: If you bet $30 on USC (+1500) to make the playoff, the bet would settle when the Trojans earn a playoff spot.
What’s the final scoring margin of the game?
For example: If you bet $30 on the Trojans -2.5 (-115) against Rutgers, USC must win the game by at least three points.
Alternatively, if you bet $40 on the Trojans +4.5 (-110) against Penn State, USC must lose by four points or less (or win the game).
Will USC win the matchup?
For example: If you bet $30 on the Trojans -175 against Washington, USC must win the game (in regulation or overtime).
How many total points (by both teams) will be scored in the game?
For example: If you bet $190 on over 58.5 (-105) in their game against Northwestern, the teams must combine for at least 59.
Alternatively, if you bet $170 on under 57.5 (-115), the teams must combine for 57 points or fewer.
If the combined point total is the same as the over/under total, the bet is a push.
At BetMGM, you may combine multiple bets — for college football or another sport — into parlays.
For example: If you bet $10 on a two-leg parlay with the USC football moneyline (-250) vs. Nebraska and over 60.5 (-110) in the Michigan State-Iowa game, both must hit for the bet to cash.
If one bet is a push, it’s eliminated from the parlay, and odds (and payout) are recalculated without that leg.
Read the latest betting tips and how-to guides from BetMGM experts.
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