LSU vs South Carolina Prediction, Odds & Best Prop Bets โ€“ NCAAF, Week 3

South Carolina head coach Shane Beamer reacts to a call during the second quarter of the Gator Bowl NCAA college football game against Notre Dame on Friday, Dec. 30, 2022, in Jacksonville, Fla. (AP Photo/Gary McCullough)
(AP Photo/Gary McCullough)
  • LSU is a -7 point favorite vs. South Carolina
  • LSU vs. South Carolina Total(Over/Under): 50.5 points
  • TV Channel: ABC

The LSU Tigers (1-1) visit Williams-Brice Stadium to take on the South Carolina Gamecocks (2-0) on Sep. 14 in Columbia, SC. Kickoff is scheduled for 12:00pm EDT.

LSU is a betting favorite in Week 3, with the spread sitting at -7 (-110).

The LSU vs. South Carolina Over/Under is 50.5 total points.

Bet now on South Carolina vs LSU & all NCAAF games with BetMGM

LSU vs. South Carolina Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
LSU-7 -11050.5 -110-250
South Carolina +7 -11050.5 -110+210

LSU vs South Carolina Prediction:

The winning team model predicts LSU will win this game with 69.1% confidence, based on game simulations, offensive & defensive matchups and recent game results.

LSU vs South Carolina Spread Prediction:

Based on recent against-the-spread trends, the model predicts South Carolina will cover the spread with 51.0% confidence.

Both predictions factor in up-to-date player injuries for both LSU and South Carolina and key player performances this season.


Bet now on South Carolina vs LSU and all games with BetMGM


  • LSU has hit the Game Total Over in 11 of their last 13 games (+8.80 Units / 62% ROI)
  • LSU has hit the Moneyline in 9 of their last 12 games (+4.90 Units / 0% ROI)
  • LSU has hit the 1H Game Total Over in their last 4 away games (+4.00 Units / 93% ROI)
  • LSU has hit the 1Q Game Total Over in their last 3 away games (+3.00 Units / 85% ROI)
  • LSU has hit the 1Q Moneyline in 4 of their last 7 games (+0.60 Units / 2% ROI)
  • South Carolina has hit the 1Q Moneyline in 9 of their last 12 games (+11.40 Units / 55% ROI)
  • South Carolina has hit the 1H Moneyline in 7 of their last 12 games (+10.55 Units / 40% ROI)
  • South Carolina have covered the 1Q Spread in 8 of their last 12 games (+4.95 Units / 38% ROI)
  • South Carolina has hit the Game Total Under in 8 of their last 12 games (+3.60 Units / 27% ROI)
  • South Carolina has hit the Moneyline in 5 of their last 7 games at home (+2.90 Units / 9% ROI)

We’ve highlighted some favorite college football player prop bets for LSU players, looking at profitable historical betting trends:

Best LSU Player Prop Bets Today

  • Mason Taylor has hit the Receiving Yards Under in his last 4 games (+4.00 Units / 82% ROI)
  • Kyren Lacy has hit the Receiving Yards Over in his last away game (+1.00 Units / 91% ROI)
  • Garrett Nussmeier has hit the Passing Yards Over in his last game (+1.00 Units / 83% ROI)
  • Garrett Nussmeier has hit the TD Passes Over in his last game (+1.00 Units / 47% ROI)

Top NCAAF player prop bets for South Carolina players, looking at profitable historical betting trends:

Best South Carolina Player Prop Best Bets Today

  • no trends found

LSU Against the Spread (ATS) Record

LSU is 0-2 against the spread this college football season (-2.2 Units / -100% ROI).

  • LSU is 0-1 when betting on the Moneyline for -1.7 Units / -100% ROI
  • LSU is 1-1 when betting the Over for -0.1 Units / -4.55% ROI
  • LSU is 1-1 when betting the Under for -0.1 Units / -4.55% ROI

South Carolina Against the Spread (ATS) Record

South Carolina is 1-1 against the spread this college football season (-0.1 Units / -4.55% ROI).

  • South Carolina is 2-0 when betting on the Moneyline for +3.9 Units / 25.91% ROI
  • South Carolina is 0-2 when betting the Over for -2.2 Units / -100% ROI
  • South Carolina is 2-0 when betting the Under for +2 Units / 90.91% ROI

LSU: Keys to the Game vs. South Carolina

LSU is 5-1 (.714) when rushing more than 30 times since the 2023 season– T-27th-best in FBS; Average: .517

LSU is 4-1 (.571) when rushing more than 30 times since the 2023 season– T-13th-best among Power Conference Teams; Average: .426

LSU is 8-2 (.727) when rushing for 120 or more yards since the 2023 season– T-25th-best in FBS; Average: .549

LSU is 5-2 (.556) when committing less than 60 yards in penalties since the 2023 season– T-37th-best in FBS; Average: .438

South Carolina: Keys to the Game vs. LSU

South Carolina is winless (0-5) when allowing an average of more than 5 yards on first down plays since the 2023 season– T-worst in FBS; Average: .425

South Carolina is winless (0-5) when allowing an average of more than 5 yards on first down plays since the 2023 season– T-worst among Power Conference Teams; Average: .431

South Carolina is 5-2 (.625) when rushing at least 4 yards in a play 10 or more times since the 2023 season– T-30th-best in FBS; Average: .482

South Carolina is 1-6 (.143) when allowing 7 or more explosive plays since the 2023 season– T-22nd-worst in FBS; Average: .389

Matchup Notes for LSU vs. South Carolina

South Carolina’s QBs has thrown for 280 passing yards in 2 games (just 140.0 YPG) this season — 14th-worst among FBS teams. LSU’s defense has allowed 261.5 passing yards per game this season — 23rd-worst among FBS defenses.

South Carolina’s offense has thrown for 280 passing yards in 2 games (just 140.0 YPG) this season — 12th-worst among FBS offenses. LSU’s defense has allowed 261.5 passing yards per game this season — 23rd-worst among FBS defenses.

South Carolina’s RBs has 1 receptions in 2 games (just 0.5 per game) this season — T-2nd-worst among FBS RBs. LSU’s defense has allowed 21.5 receptions per game this season — T-28th-worst among FBS defenses.

LSU’s offense has thrown for 618 passing yards in 2 games (309.0 YPG) this season — 22nd-best among FBS offenses. South Carolina’s defense has allowed just 120.5 passing yards per game this season — 20th-best among FBS defenses.

LSU’s QBs has thrown for 618 passing yards in 2 games (309.0 YPG) this season — 22nd-best among FBS teams. South Carolina’s defense has allowed just 120.5 passing yards per game this season — 20th-best among FBS defenses.

LSU have 301.0 receiving yards per game this season — T-23rd-best among FBS skill players. South Carolina’s defense has allowed just 120.5 receiving yards per game this season — 20th-best among FBS defenses.

LSU Offensive Stats & Trends

LSU WRs have caught 46 touchdown passes since the 2023 season– most among SEC Teams

LSU WRs have 23 receptions for 20 or more yards in the 4th quarter since the 2023 season– most among SEC Teams

LSU Skill Players have 25 receptions for 20 or more yards in the 4th quarter since the 2023 season– most among SEC Teams

LSU WRs have caught 5 touchdown passes in the Red Zone this season– T-most among FBS Teams

LSU Skill Players have averaged 17.3 yards per reception (1,092 yards/63 catches) in the 4th quarter since the 2023 season– best among Power Conference Teams; Average: 12.4

South Carolina Offensive Stats & Trends

South Carolina’s QBs has thrown for 280 passing yards in 2 games (just 140.0 YPG) this season — 14th-worst among FBS teams. LSU’s defense has allowed 261.5 passing yards per game this season — 23rd-worst among FBS defenses.

South Carolina’s offense has thrown for 280 passing yards in 2 games (just 140.0 YPG) this season — 12th-worst among FBS offenses. LSU’s defense has allowed 261.5 passing yards per game this season — 23rd-worst among FBS defenses.

South Carolina TEs have 5 receptions for 20 or more yards in the 4th quarter since the 2023 season– T-3rd-most among FBS Teams

South Carolina RBs have averaged just 3.5 Yards per Carry (376 yards/108 carries) in the 4th quarter since the 2022 season– T-3rd-worst among FBS Teams; Average: 5.0

South Carolina have been sacked on 18% of pass attempts (7/39) this season– worst among Power Conference Offenses; Average: 5%

LSU Tigers Defensive Stats & Trends

LSU has allowed a Completion Pct of 75% (42 completions/56 attempts) on 3rd and long since the 2023 season– worst among Power Conference Teams; Average: 53%

LSU has allowed opponents to catch 42 of 56 passes (75% Reception Pct) on 3rd and long since the 2023 season– T-worst in FBS; Average: 55%

LSU has no interceptions and 2 TD passes allowed this season– T-worst in the SEC; Average: 0.6

LSU has allowed a Completion Pct of 75% (42 completions/56 attempts) on 3rd and long since the 2023 season– worst in the SEC; Average: 55%

LSU has allowed 4 rushing TDs this season– most in the SEC

South Carolina Gamecocks Defensive Stats & Trends

South Carolina has sacked opposing QBs just once on 45 pass attempts in the Red Zone since the 2023 season– worst in the SEC; Average: 12.8

South Carolina has forced 6 fumbles this season– T-most in FBS

South Carolina has forced 6 fumbles this season– most among Power Conference Teams

South Carolina has averaged 5.0 sacks per game this season– best in the SEC; Average: 2.3

South Carolina has tackled opponents for a loss on just 16 of 168 rushing attempts (10% TFL%) in the Red Zone since the 2022 season– worst in the SEC; Average: 15%.


Bet now on South Carolina vs LSU and all games with BetMGM


More College Football Betting at BetMGM

BetMGM is the best online sportsbook for college football betting.

Whether youโ€™re a first-time bettor checking out the best sportsbook promos, a casual fan betting on Georgia national championship odds, Tennessee football’s playoff odds, or Ohio State odds, or a longtime diehard breaking down trends for live sports betting, there are entertainment options for everyone.

Visit the sportsbook today to place a college football bet online!

BetMGM First Bet Offer
About the Author

Shane Jackson

Read More @Sjacksonmgm

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.