Louisville vs Duke Prediction, Odds & Best Bets Today – NCAAB, Feb. 28

Duke head coach Jon Scheyer watches from the sideline against North Carolina State during the first half of an NCAA college basketball game in Raleigh, N.C., Wednesday, Jan. 4, 2023.
(AP Photo/Karl B DeBlaker)
  • Duke (15-11) is a -20.5 point favorite vs Louisville (12-14)
  • Total (Over/Under): 151.5 points
  • Louisville / Duke TV channel: ACCN

The Louisville Cardinals (12-14) visit Cameron Indoor Stadium to take on the Duke Blue Devils (15-11) on Feb. 28. Tip off is scheduled for 7:00pm EST in Durham, NC.

Duke is the betting favorite in this game, with the spread sitting at -20.5 (-110).

The Louisville vs. Duke Over/Under is 151.5 total points.

Bet now on Duke vs Louisville & all college basketball games with BetMGM

Louisville vs. Duke Odds, Spread, Over/Under

SpreadTotal (O/U)Moneyline
Louisville+20.5 -110O 151.5 -110+1450
Duke -20.5 -110U 151.5 -110-5000

Louisville vs Duke Prediction for Today:

The winning team model predicts Duke will win this college basketball game with 95.0% confidence, based on game simulations, player injuries, key player performances and recent matchups.

Louisville vs Duke Spread Prediction:

Based on recent against-the-spread trends, the spread model predicts Louisville will cover the spread with 51.4% confidence for today’s game.


Bet now on Duke vs Louisville and all games with BetMGM


  • Louisville has hit the Team Total Over in 17 of their last 30 games (+2.15 Units / 6% ROI)
  • Louisville has hit the 1H Game Total Under in 17 of their last 30 games (+1.85 Units / 5% ROI)
  • Louisville has hit the Game Total Over in 16 of their last 30 games (+0.65 Units / 2% ROI)
  • Duke has hit the 1H Moneyline in 26 of their last 33 games (+11.95 Units / 4% ROI)
  • Duke have covered the Spread in 20 of their last 34 games (+5.70 Units / 15% ROI)
  • Duke has hit the 1H Game Total Under in 20 of their last 34 games (+5.05 Units / 13% ROI)
  • Duke has hit the Game Total Under in 20 of their last 34 games (+4.60 Units / 12% ROI)
  • Duke has hit the Moneyline in 12 of their last 14 games at home (+1.95 Units / 2% ROI)

Louisville Basketball Against the Spread Record (ATS)

Louisville has a 11-13 record against the spread this college basketball season (-3.35 Units / -11.28% ROI).

  • 8-19 when betting on the Moneyline for -3.05 Units / -6.14% ROI
  • 14-13 when betting the Over for -0.25 Units / -0.84% ROI
  • 13-14 when betting the Under for -2.4 Units / -8.07% ROI

Duke Basketball Against the Spread Record (ATS)

Duke has a 15-11 record against the spread this college basketball season (+2.9 Units / 9.76% ROI).

  • 16-6 when betting on the Moneyline for -5.9 Units / -4.04% ROI
  • 12-15 when betting the Over for -4.45 Units / -15.01% ROI
  • 15-12 when betting the Under for +1.8 Units / 6.05% ROI

Louisville Offensive Stats & Trends:

Louisville has an assist to turnover ratio of 0.6 (259 assists/ 420 TOs) in the first half since the start of the 2022-23 season — lowest among ACC Teams; League Avg: 1.2

Louisville has averaged 14.3 turnovers per game (473 turnovers/33 games) at home since the start of the 2022-23 season — highest among ACC Teams; League Avg: 10.7

Louisville has an assist to turnover ratio of 0.7 (326 assists/ 473 TOs) at home since the start of the 2022-23 season — lowest among ACC Teams; League Avg: 1.3

Louisville has averaged 14.1 turnovers per game (773 turnovers/55 games) since the start of the 2022-23 season — highest among ACC Teams; League Avg: 11.1

Duke Offensive Stats & Trends:

Duke has an assist to turnover ratio of 1.7 (365 assists/ 221 TOs) this season — tied for 8th best among Division 1 Teams; League Avg: 1.1

Duke is shooting 41% from three (100/241) in the second half this season — best among ACC Teams; League Avg: 35%

Duke has an assist to turnover ratio of 1.9 (193 assists/ 102 TOs) in the second half this season — best among ACC Teams; League Avg: 1.3

Duke is shooting 48% (664/1,374) this season — 16th best among Division 1 Teams; League Avg: 45%

Louisville Defensive Stats & Trends:

Louisville has allowed opponents to shoot 48% (332/695) in the first half this season — highest among ACC Teams; League Avg: 41%

Louisville has averaged 4.9 steals per game (271 steals/55 games) since the start of the 2022-23 season — 4th lowest among Power Conference teams; League Avg: 6.6

Louisville has allowed opponents to shoot 47% (776/1,648) in the first half since the start of the 2022-23 season — highest among ACC Teams; League Avg: 42%

Louisville has allowed an average of 1.42 points per shot (1,771 points/1,249 shots) on the road since the start of the 2022-23 season — highest among ACC Teams; League Avg: 1.26

Duke Defensive Stats & Trends:

Duke has averaged 26.5 defensive rebounds per game (609 rebounds/23 games) this season — tied for 41st best among Division 1 Teams; League Avg: 24.7

Duke has averaged 26.7 defensive rebounds per game (1,573 rebounds/59 games) since the start of the 2022-23 season — tied for 28th best among Division 1 Teams; League Avg: 24.3

Duke has allowed opponents to shoot 31% from three (388/1,242) since the start of the 2022-23 season — 14th best among Division 1 Teams; League Avg: 34%

Duke has allowed an average of 1.13 points per shot (3,843 points/3,406 shots) since the start of the 2022-23 season — tied for best among ACC Teams; League Avg: 1.20


Bet now on Duke vs Louisville and all games with BetMGM


College Basketball Betting at BetMGM

At the best online sportsbook, you can bet on updated college basketball betting odds, including parlays and live sports betting. The best online sports betting and mobile sports betting (with the BetMGM Sportsbook app) experiences are at BetMGM.

Log in to your account now for updated sportsbook promos in your state. If you donโ€™t have an account, check out BetMGMโ€™s welcome offer.

betmgm-nco-jamie-foxx
About the Author

BetMGM Betting

Read More @BETMGM

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.