Guardians vs Orioles Prediction, Odds & Player Prop Bets Today – MLB, Jun 26

Baltimore Orioles' Anthony Santander in action during a baseball game against the Texas Rangers, Sunday, May 28, 2023, in Baltimore.
(AP Photo/Nick Wass)
  • The Orioles are -190 favorites vs the Guardians
  • Guardians vs Orioles Over / Under today: 9.5 Runs
  • Guardians / Orioles TV Channel: BSGL

The Cleveland Guardians (+155) visit Oriole Park at Camden Yards to take on the Baltimore Orioles (-190) on Wednesday, June 26, 2024. First pitch is scheduled for 6:35pm EDT in Baltimore, MD.

This season, the Guardians are 51-26 against the spread (ATS), while the Orioles are 45-34 ATS.

Guardians vs Orioles Starting Pitchers Today:

  • Guardians starting pitcher: Carlos Carrasco 3-6, 5.40 ERA
  • Orioles starting pitcher: Grayson Rodriguez 8-3, 3.84 ERA

Guardians vs. Orioles Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Guardians+1.5 -120O 9 -105+155
Orioles -1.5 +100U 9 -115-190

Guardians vs Orioles Prediction for Today’s Game

Based on recent trends the model predicts the Orioles will win Wednesday‘s MLB game with 59.8% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Guardians players for Wednesday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

  • Steven Kwan has hit the Home Runs Over in 4 of his last 15 games (+38.00 Units / 253% ROI)
  • Jose Ramirez has hit the Runs Over in 32 of his last 43 games (+20.65 Units / 42% ROI)
  • Jose Ramirez has hit the RBIs Over in 26 of his last 42 games (+16.45 Units / 39% ROI)
  • Steven Kwan has hit the Hits Runs and RBIs Over in 16 of his last 17 games (+14.85 Units / 59% ROI)
  • Jose Ramirez has hit the Hits Over in 25 of his last 42 games (+11.30 Units / 17% ROI)

And here are some favorite MLB player prop bets for Orioles players for Wednesday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Best Bets Today:

  • Anthony Santander has hit the Home Runs Over in 13 of his last 31 games (+31.25 Units / 101% ROI)
  • Gunnar Henderson has hit the Hits Over in 14 of his last 16 games at home (+15.95 Units / 53% ROI)
  • Anthony Santander has hit the RBIs Over in 15 of his last 24 games (+14.05 Units / 59% ROI)
  • Gunnar Henderson has hit the Total Bases Over in 19 of his last 26 games (+12.80 Units / 43% ROI)
  • Ryan O’Hearn has hit the Singles Over in 19 of his last 25 games at home (+12.00 Units / 40% ROI)
  • The Cleveland Guardians have hit the Moneyline in 51 of their last 77 games (+20.97 Units / 21% ROI)
  • The Cleveland Guardians have covered the Run Line in 45 of their last 77 games (+18.90 Units / 20% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 49 of their last 77 games (+18.15 Units / 19% ROI)
  • The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 39 of their last 63 games (+14.35 Units / 19% ROI)
  • The Cleveland Guardians have hit the Team Total Over in 47 of their last 77 games (+12.85 Units / 14% ROI)
  • The Baltimore Orioles have covered the Run Line in 41 of their last 70 games (+18.45 Units / 22% ROI)
  • The Baltimore Orioles have covered the 1st Five Innings (F5) Run Line in 41 of their last 64 games (+14.80 Units / 19% ROI)
  • The Baltimore Orioles have hit the Team Total Over in 21 of their last 32 games (+9.30 Units / 25% ROI)
  • The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Over in 22 of their last 34 games at home (+8.85 Units / 23% ROI)
  • The Baltimore Orioles have hit the 1st Five Innings (F5) Moneyline in 21 of their last 32 games at home (+7.70 Units / 16% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 45-32 against the Run Line (+18.9 Units / 20.15% ROI).

  • 51-26 when betting on the Moneyline for +20.97 Units / 21.02% ROI
  • 37-34 when betting on the total runs Over for -0.5 Units / -0.58% ROI
  • 34-37 when betting on the total runs Under for -6.25 Units / -7.44% ROI

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are 45-34 against the Run Line (+18.3 Units / 19.95% ROI).

  • 49-30 when betting on the Moneyline for +8.6 Units / 7.73% ROI
  • 40-28 when betting on the total runs Over for +9.6 Units / 11.22% ROI
  • 28-40 when betting on the total runs Under for -16.1 Units / -18.7% ROI

Orioles vs Guardians Home Run Prop Bets Today

Over Under
Anthony Santander (BAL) 0.5 +375 0.5 -550
Gunnar Henderson (BAL) 0.5 +400 0.5 -550
Jose Ramirez (CLE) 0.5 +475 0.5 -650
Ryan Mountcastle (BAL) 0.5 +475 0.5 -650
Josh Naylor (CLE) 0.5 +500 0.5 -700

Orioles vs Guardians Total Hits Prop Bets Today

Over Under
Josh Naylor (CLE) 0.5 -275 0.5 +200
Jose Ramirez (CLE) 0.5 -275 0.5 +200
Tyler Freeman (CLE) 0.5 -250 0.5 +185
Andres Gimenez (CLE) 0.5 -250 0.5 +180
Will Brennan (CLE) 0.5 -250 0.5 +180

Orioles vs Guardians RBI Prop Bets Today

Over Under
Ryan Mountcastle (BAL) 0.5 +115 0.5 -150
Anthony Santander (BAL) 0.5 +125 0.5 -160
Jose Ramirez (CLE) 0.5 +130 0.5 -175
Gunnar Henderson (BAL) 0.5 +135 0.5 -185
Josh Naylor (CLE) 0.5 +140 0.5 -185

Orioles vs Guardians Strikeout Prop Bets Today

Over Under
Grayson Rodriguez (BAL) 4.5 -150 4.5 +115
Carlos Carrasco (CLE) 3.5 +100 3.5 -130

Carlos Carrasco has allowed a slugging percentage of .735 (122 Total Bases / 166 ABs) on inside fastballs since the 2022 season — highest in MLB among starting pitchers with at least 160 total IP; League Avg: .429 — 0 Percentile.

Carlos Carrasco has allowed an OPS of .927 (457 PA’s) versus hitters not batting 3-4-5 in the order since last season — highest in MLB among starting pitchers with at least 95 total IP; League Avg: .709 — 0 Percentile.

Opponents are hitting .386 (64-for-166) against Carlos Carrasco’s inside fastball since the 2022 season — highest in MLB among starting pitchers with at least 160 total IP; League Avg: .260 — 0 Percentile.

Carlos Carrasco has allowed a slugging percentage of .605 (95 Total Bases / 157 ABs) on elevated fastballs since the 2022 season — highest in MLB among starting pitchers with at least 160 total IP; League Avg: .381 — 0 Percentile.

Orioles Starting Pitcher Stats & Trends

Grayson Rodriguez has struck out 40% (19/47) of left-handed batters he faced this month (4 games) — 3rd best among qualified SPs in MLB; League Avg: 21% — 96th Percentile.

Grayson Rodriguez has struck out just 9% (5/54) of right-handed batters he faced this month (4 games) — 2nd lowest among qualified SPs in MLB; League Avg: 22% — second Percentile.

Grayson Rodriguez has a first-pitch strike rate of 83% (45/54) — highest in MLB over the last two weeks; League Avg: 65% — 100th Percentile.

Opponents are hitting .439 (43-for-98) against Grayson Rodriguez on the first pitch of at-bats since last season — 6th highest in MLB among starting pitchers with at least 95 total IP; League Avg: .345 — fourth Percentile.

Guardians Keys to the Game vs. the Orioles

The Guardians are 15-10 (.600) when allowing 2 or more home runs this season — best in MLB; League Avg: .306.

The Guardians are 9-10 (.474) when allowing 10 or more hits this season — best in MLB; League Avg: .247.

The Guardians are 44-1 (.978) when leading entering the 8th inning this season — best in MLB; League Avg: .892.

The Guardians are 37-135 (.215) when trailing entering the 7th inning since the 2022 season — best in MLB; League Avg: .133.

Orioles Keys to the Game vs. the Guardians

The Orioles are 31-23 (.574) after a win as underdogs since the 2023 season — 3rd best in MLB; League Avg: .420.

The Orioles are 18-7 (.720) when tied entering the 7th inning since the 2023 season — best in MLB; League Avg: .500.

The Orioles are 74-20 (.787) when they’ve hit 2 or more home runs since the 2023 season — best in MLB; League Avg: .691.

The Orioles are 50-27 (.649) after a road win since the 2023 season — best in MLB; League Avg: .480.

The Guardians are batting just .281 on the first pitch of at-bats this season — 2nd lowest in MLB; League Avg: .332.

The Guardians are batting .324 when facing the starting pitcher for the 3rd time in a game this season — best in MLB; League Avg: .266.

Guardians hitters have missed on just 22% of swings since the 2022 season — best in MLB; League Avg: 26%.

Guardians hitters had a Hard-Hit Rate of just 33% in the 2023 season — lowest in MLB; League Avg: 40%.

Orioles hitters are slugging .282 on pitches out of the zone this season — best in MLB; League Avg: .211.

Orioles hitters are slugging .459 this season — best in MLB; League Avg: .393.

Orioles hitters have an OPS of .815 (946 PA’s) in innings 7-9 this season — best in MLB; League Avg: .682.

Orioles hitters have put just 35% of balls in play to the left side of the field since last season — 2nd lowest in MLB; League Avg: 39%.

The Guardians have allowed 0.66 runs per game (51/77) in late innings this season — best in MLB; League Avg: 1.29.

Opponents have a groundball batting average of just .190 against Guardians pitchers with runners on base this season — best in MLB; League Avg: .259.

Guardians pitchers have won 50% of games in which they have allowed their opponent to score in three different innings this season — highest in MLB; League Avg: 26%.

Opponents have a miss rate of 27% against Guardians pitchers this season — 5th best in MLB; League Avg: 25%.

The Orioles have won 48% of road games in which their opponents scored first since last season — highest in MLB; League Avg: 28%.

Orioles pitchers have walked 44 of 713 batters (6%) when facing the leadoff batter in the inning this season — 3rd best in MLB; League Avg: 7%.

Orioles pitchers have walked 242 of 3,608 batters (7%) when facing the leadoff batter in the inning since the 2022 season — 4th best in MLB; League Avg: 8%.

Opponents have a groundball batting average of just .203 against Orioles pitchers with the shift since last season — best in MLB; League Avg: .241.

Orioles vs. Guardians Injuries Tonight That May Affect Prop Bets 

  • Felix Bautista (Baltimore Orioles): Elbow, 60-Day IL
  • Terrin Vavra (Baltimore Orioles): Shoulder, Day-To-Day
  • John Means (Baltimore Orioles): Forearm, 15-Day IL
  • Kyle Bradish (Baltimore Orioles): Elbow, 15-Day IL
  • Cionel Perez (Baltimore Orioles): Oblique, 15-Day IL
  • Daniel Espino (Cleveland Guardians): Shoulder, Out
  • Gavin Williams (Cleveland Guardians): Elbow, 15-Day IL
  • Ben Lively (Cleveland Guardians): Illness, 15-Day IL
  • Luis Ortiz (Cleveland Guardians): Ankle, 15-Day IL
  • Xzavion Curry (Cleveland Guardians): Illness, 15-Day IL
  • Joey Cantillo (Cleveland Guardians): Hamstring, Out
  • Angel Martinez (Cleveland Guardians): Foot, 10-Day IL
  • Sam Hentges (Cleveland Guardians): Finger, 15-Day IL
  • Trevor Stephan (Cleveland Guardians): Elbow, 60-Day IL
  • George Valera (Cleveland Guardians): Hamstring, Out
  • James Karinchak (Cleveland Guardians): Shoulder, 60-Day IL

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About the Author

Shane Jackson

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Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.