Pirates vs Reds Prediction, Odds & Player Prop Bets Today – MLB, Sep 22

Cincinnati Reds' Elly De La Cruz watches his hit during the first inning of a spring training baseball game against the Cleveland Guardians, Saturday, Feb. 24, 2024, in Goodyear, Ariz.
(AP Photo/Carolyn Kaster)
  • The Pirates are -120 favorites vs the Reds
  • Pirates vs Reds Over / Under today: 8 Runs
  • Pirates / Reds TV Channel: BSOH | SNPT

The Pittsburgh Pirates (-120) visit Great American Ball Park to take on the Cincinnati Reds (+100) on Sunday, September 22, 2024. First pitch is scheduled for 1:10pm EDT in Cincinnati, OH.

This season, the Pirates are against the spread (ATS), while the Reds are ATS.

Pirates vs Reds Starting Pitchers Today:

  • Pirates starting pitcher: Paul Skenes 10-3, 2.07 ERA
  • Reds starting pitcher: Hunter Greene 9-4, 2.83 ERA

Pirates vs. Reds Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Pirates-1.5 +145O 8 -115-120
Reds +1.5 -175U 8 -105+100

Pirates vs Reds Prediction for Today’s Game

Based on recent trends the model predicts the Pirates will win Sunday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


Bet now on Pirates vs Reds and all games with BetMGM


We’ve highlighted some favorite MLB player prop bets for Pirates players for Sunday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Bets Today:

  • Bryan Reynolds has hit the Runs Under in 35 of his last 50 games (+13.95 Units / 19% ROI)
  • Billy Cook has hit the Home Runs Over in 2 of his last 4 games (+12.30 Units / 308% ROI)
  • Yasmani Grandal has hit the Walks Over in 8 of his last 10 games (+11.15 Units / 112% ROI)
  • Bryan Reynolds has hit the Hits Runs and RBIs Under in 13 of his last 16 away games (+10.40 Units / 62% ROI)
  • Bryan Reynolds has hit the Hits Under in 8 of his last 11 away games (+9.20 Units / 59% ROI)

And here are some favorite MLB player prop bets for Reds players for Sunday‘s game, looking at profitable historical betting trends:

Best Reds Player Prop Best Bets Today:

  • TJ Friedl has hit the Home Runs Over in 3 of his last 13 games (+17.75 Units / 137% ROI)
  • Santiago Espinal has hit the Total Bases Under in 13 of his last 16 games (+11.65 Units / 48% ROI)
  • Elly De La Cruz has hit the Walks Under in 20 of his last 25 games at home (+11.05 Units / 24% ROI)
  • Spencer Steer has hit the Singles Under in 12 of his last 13 games (+10.90 Units / 62% ROI)
  • Will Benson has hit the Runs Over in 8 of his last 11 games at home (+9.35 Units / 85% ROI)
  • The Pittsburgh Pirates have hit the 1st Five Innings (F5) Team Total Under in 12 of their last 17 away games (+7.20 Units / 38% ROI)
  • The Pittsburgh Pirates have covered the Run Line in 63 of their last 115 games (+7.07 Units / 5% ROI)
  • The Pittsburgh Pirates have hit the Game Total Under in 38 of their last 69 away games (+6.50 Units / 9% ROI)
  • The Pittsburgh Pirates have hit the Team Total Under in 13 of their last 19 away games (+6.40 Units / 29% ROI)
  • The Cincinnati Reds have hit the Team Total Under in 41 of their last 64 games at home (+15.60 Units / 21% ROI)
  • The Cincinnati Reds have covered the Run Line in 79 of their last 137 games (+14.45 Units / 8% ROI)
  • The Cincinnati Reds have hit the Moneyline in 11 of their last 18 games (+7.75 Units / 42% ROI)
  • The Cincinnati Reds have hit the Game Total Over in 35 of their last 64 games (+7.55 Units / 11% ROI)
  • The Cincinnati Reds have hit the 1st Five Innings (F5) Team Total Under in 44 of their last 76 games at home (+5.85 Units / 6% ROI)

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are against the Run Line ( Units / ROI).

  • away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
  • away total over record when betting on the total runs Over for over units Units / over ROI ROI
  • away total under record when betting on the total runs Under for under units Units / under ROI ROI

Reds Against the Spread (ATS) Record

Against the spread this season, the Reds are against the Run Line ( Units / ROI).

  • home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
  • home total over record when betting on the total runs Over for over units Units / over ROI ROI
  • home total under record when betting on the total runs Under for under units Units / under ROI ROI

Reds vs Pirates Home Run Prop Bets Today

Over Under
Oneil Cruz (PIT) 0.5 +275 0.5 -350
Andrew McCutchen (PIT) 0.5 +400 0.5 -550
Joey Bart (PIT) 0.5 +450 0.5 -650
Bryan De La Cruz (PIT) 0.5 +450 0.5 -650
Rowdy Tellez (PIT) 0.5 +475 0.5 -650

Reds vs Pirates Total Hits Prop Bets Today

Over Under
Ty France (CIN) 0.5 -225 0.5 +170
Tyler Stephenson (CIN) 0.5 -210 0.5 +160
Oneil Cruz (PIT) 0.5 -210 0.5 +160
Joey Bart (PIT) 0.5 -210 0.5 +160
Jonathan India (CIN) 0.5 -200 0.5 +150

Reds vs Pirates RBI Prop Bets Today

Over Under
Oneil Cruz (PIT) 0.5 +150 0.5 -200
Andrew McCutchen (PIT) 0.5 +160 0.5 -210
Ty France (CIN) 0.5 +175 0.5 -250
Joey Bart (PIT) 0.5 +175 0.5 -250
Spencer Steer (CIN) 0.5 +180 0.5 -250

Reds vs Pirates Strikeout Prop Bets Today

Over Under
Paul Skenes (PIT) 6.5 -115 6.5 -110
Hunter Greene (CIN) 4.5 +105 4.5 -140

Opponents have a groundball rate of 79% (22/28) against Paul Skenes in his last two starts — highest in MLB over the last two weeks; League Avg: 42% — 100th Percentile.

Opponents had a groundball rate of 86% (12/14) against Paul Skenes in his last start — highest in MLB over the last week; League Avg: 44% — 100th Percentile.

Right-handed hitters have a groundball rate of 77% (13/17) against Paul Skenes in his last two starts — highest in MLB over the last two weeks; League Avg: 43% — 100th Percentile.

Paul Skenes has a strikeout rate of 38% (72 SO in 189 PAs) when going through the lineup the first time in a game this season — 2nd best in MLB among starting pitchers with at least 61 total IP; League Avg: 24% — 99th Percentile.

Reds Starting Pitcher Stats & Trends

Opponents have a miss rate of 39% (81/210) against Hunter Greene on the first pitch of at-bats this season — best in MLB among starting pitchers with at least 61 total IP; League Avg: 25% — 100th Percentile.

Opponents are hitting just .196 against Hunter Greene vs right-handed batters this season — tied for 11th best among starting pitchers with at least 61 total IP– 91st Percentile. Right handed batters hit .288 (66-for-229) against him last season — 12th worst among starting pitchers with at least 64 total IP– ninth Percentile.

Hunter Greene has struck out 32% (93/291) of left-handed batters he faced this season — 3rd best in MLB among starting pitchers with at least 61 total IP; League Avg: 22% — 97th Percentile.

Opponents are hitting just .197 (12-for-61) against Hunter Greene when he’s behind in the count this season — best in MLB among starting pitchers with at least 61 total IP; League Avg: .343 — 100th Percentile.

Pirates Keys to the Game vs. the Reds

The Pirates are just 60-7 (.896) when leading entering the 9th inning this season — 2nd lowest in MLB; League Avg: .949.

The Pirates are just 18-30 (.375) when tied entering the 8th inning since the 2022 season — lowest in MLB; League Avg: .500.

The Pirates are just 6-43 (.122) when allowing 10 or more hits this season — 2nd lowest in MLB; League Avg: .250.

The Pirates are just 36-136 (.209) when allowing 10 or more hits since the 2022 season — 5th lowest in MLB; League Avg: .265.

Reds Keys to the Game vs. the Pirates

The Reds are just 34-37 (.479) after a loss as favorites since the 2022 season — 2nd lowest in MLB; League Avg: .589.

The Reds are just 5-15 (.250) when tied entering the 8th inning this season — lowest in MLB; League Avg: .500.

The Reds are just 13-26 (.333) when tied entering the 8th inning since the 2023 season — lowest in MLB; League Avg: .500.

The Reds are just 33-45 (.423) when tied entering the 7th inning since the 2022 season — 5th lowest in MLB; League Avg: .500.

Pirates hitters have 89 strikeouts in 254 PA’s (35%) in lefty-lefty matchups this season — highest in MLB; League Avg: 24%.

Pirates hitters are slugging just .497 on the first pitch of at-bats since the 2022 season — lowest in MLB; League Avg: .572.

Pirates hitters have 1,363 strikeouts in 5,362 PA’s (25%) against LHP since the 2022 season — highest in MLB; League Avg: 22%.

Pirates hitters have 447 strikeouts in 1,331 PA’s (34%) in lefty-lefty matchups since the 2022 season — highest in MLB; League Avg: 24%.

team hitters – home

Pirates pitchers have 252 three-pitch strikeouts this season — 3rd most in MLB.

Pirates pitchers have walked 1,672 of 18,405 batters (9%) since the 2022 season — 5th highest in MLB; League Avg: 8%.

Opponents have a miss rate of just 25% against Pirates pitchers since last season — 5th lowest in MLB; League Avg: 26%.

The longest HR allowed by the Pirates pitchers in the 2023 season traveled 454.0 feet — — 2nd shortest in MLB; League Avg: 465.8

Opponents have a groundball rate of just 30% against Reds pitchers over the past seven days (6 games) — lowest in MLB; League Avg: 43%.

Opponents have a groundball rate of just 39% against Reds pitchers since last season — lowest in MLB; League Avg: 43%.

Opponents have a groundball batting average of .295 against Reds pitchers with runners on base since the 2022 season — highest in MLB; League Avg: .256.

Opponents have a groundball rate of just 40% against Reds pitchers since the 2022 season — lowest in MLB; League Avg: 43%.

Reds vs. Pirates Injuries Tonight That May Affect Prop Bets 

  • Cincinnati Reds – No Injuries Reported
  • Pittsburgh Pirates – No Injuries Reported

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About the Author

Shane Jackson

Read More @Sjacksonmgm

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.