How to Bet on Week 1 NFL Odds

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Cincinnati Bengals quarterback Joe Burrow (9) and Cincinnati Bengals wide receiver Ja'Marr Chase (1) celebrate during an NFL football game against the Baltimore Ravens, Sunday, Oct. 24, 2021 in Baltimore, Md. (AP Photo/Daniel Kucin Jr.)
(AP Photo/Daniel Kucin Jr.)
BetMGM @BETMGM Jul 08, 2022, 2:04 AM

The NFL is back with a 17-game schedule and more NFL betting opportunities than ever. At BetMGM, you can view weekly NFL odds, including the spread, over/under total, and more for each Week 1 game. 

Whether you’re a Cincinnati Bengals fan betting on Joe Burrow and Ja’Marr Chase to cover the spread against Najee Harris and the Pittsburgh Steelers, a casual NFL fan building moneyline parlays with the Philadelphia Eagles, Kansas City Chiefs, and Green Bay Packers, or a longtime diehard betting on player props for Dalvin Cook and Kyler Murray, there’s something for everyone.

Week 1 NFL Schedule & Odds

Shortly after the 2022 NFL schedule was released in May, Week 1 NFL odds were posted at the online sportsbook. You can view all updated odds on the NFL betting page (odds as of July 7):

Matchup & SpreadTotalMoneyline
Bills (-1) at Rams52.5BUF -110, LAR -110
Ravens (-5.5) at Jets 45.5BAL -225, NYJ +175
Saints (-5.5) at Falcons41.5NO -225, ATL +185
Patriots at Dolphins (-2.5)44.5NE +120, MIA -145
Steelers at Bengals (-6.5)44.5PIT +225, CIN -275
49ers (-6.5) at Bears42.5SF -275, CHI +220
Eagles (-4.5) at Lions46.5PHI -190, DET +155
Colts (-7.5) at Texans44.5IND -375, HOU +290
Jaguars at Commanders (-3.5)43.5JAC +155, WAS -190
Chiefs (-3) at Cardinals53.5KC -160, ARI +130
Raiders at Chargers (-4)51.5LV +155, LAC -190
Packers (-2.5) at Vikings49.5GB -135, MIN +110
Giants at Titans (-6.5)43.5NYG +240, TEN -300
Bucs (-2.5) at Cowboys52.5TB -135, DAL +110
Broncos (-4.5) at Seahawks41.5DEN -225, SEA +180

How to Bet on Week 1 NFL Odds

You can bet on Week 1 NFL odds with online sports betting from your computer or mobile sports betting from your phone with the BetMGM Sportsbook app.

  1. Click the NFL logo on the top navigation bar.

2. Browse all odds for Week 1 games, starting with the Bills-Rams game on Thursday Night Football and ending with the Broncos-Seahawks game on Monday Night Football. 

3. Add one or multiple wagers to your bet slip when you’ve spotted a favorable number.

4. Add a wager amount, aka stake, for each bet, or combine your selections on a parlay by clicking “Parlay” at the top of the bet slip.

5. When you’re ready, click “Place Bet.”

6. Watch your bets in action on Thursday, Sunday, and Monday!

More NFL Odds

Week 1 is just the start of your NFL betting experience at BetMGM. Throughout the season, you can view updated NFL futures, including Super Bowl odds and NFL MVP odds, and weekly NFL betting lines. 

You also have access to live sports betting, a unique and exhilarating experience that allows you to place live bets during each preseason, regular-season, and postseason game.

Check out BetMGM’s live sports betting and get ready to bet online after kickoff.

Jamie Foxx holding a mobile phone next to the BetMGM's risk-free bet offer.