Guardians vs Astros Prediction, Odds & Player Prop Bets Today – MLB, May 1

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Houston Astros' Jeremy Pena reacts after flying out during the seventh inning of Game 1 of the baseball AL Championship Series against the Texas Rangers Sunday, Oct. 15, 2023, in Houston.
(AP Photo/David J. Phillip)
BetMGM Betting @BETMGM May 01, 2024, 11:00 AM
  • The Astros are -175 favorites vs the Guardians
  • Guardians vs Astros Over / Under today: 8.5 Runs
  • Guardians / Astros TV Channel: BSGL | SCHN | MLBN

The Cleveland Guardians (+145) visit Minute Maid Park to take on the Houston Astros (-175) on Wednesday, May 1, 2024. First pitch is scheduled for 8:10pm EDT in Houston, TX.

This season, the Guardians are 19-10 against the spread (ATS), while the Astros are 10-19 ATS.

Guardians vs Astros Starting Pitchers Today:

  • Guardians starting pitcher: Triston McKenzie 2-2, 4.84 ERA
  • Astros starting pitcher: Justin Verlander 1-0, 1.74 ERA

Guardians vs. Astros Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Guardians+1.5 -135O 8.5 -105+145
Astros -1.5 +110U 8.5 -115-175

Guardians vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Wednesday‘s MLB game with 54.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Guardians players for Wednesday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

  • Josh Naylor has hit the Home Runs Over in 6 of his last 19 games (+18.10 Units / 95% ROI)
  • Will Brennan has hit the Singles Under in 12 of his last 13 games (+12.90 Units / 97% ROI)
  • Jose Ramirez has hit the RBIs Over in 16 of his last 28 games (+10.80 Units / 39% ROI)
  • Josh Naylor has hit the Hits Under in 11 of his last 14 games (+10.10 Units / 38% ROI)
  • Steven Kwan has hit the Hits Runs and RBIs Over in 20 of his last 28 games (+9.80 Units / 26% ROI)

And here are some favorite MLB player prop bets for Astros players for Wednesday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

  • Yordan Alvarez has hit the Hits Under in 18 of his last 28 games (+16.00 Units / 41% ROI)
  • Jose Altuve has hit the Home Runs Over in 4 of his last 11 games at home (+15.80 Units / 144% ROI)
  • Kyle Tucker has hit the Total Bases Over in 17 of his last 28 games (+9.10 Units / 31% ROI)
  • Yordan Alvarez has hit the Hits Runs and RBIs Under in 19 of his last 28 games (+8.85 Units / 26% ROI)
  • Yordan Alvarez has hit the RBIs Under in 12 of his last 14 games at home (+8.20 Units / 34% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 75 of their last 134 games (+14.05 Units / 10% ROI)
  • The Cleveland Guardians have covered the Run Line in 34 of their last 60 away games (+6.30 Units / 8% ROI)
  • The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 25 of their last 44 away games (+5.36 Units / 11% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Moneyline in 22 of their last 44 away games (+5.35 Units / 11% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 20 of their last 34 games (+4.72 Units / 12% ROI)
  • The Houston Astros have hit the Game Total Over in 37 of their last 61 games (+15.00 Units / 22% ROI)
  • The Houston Astros have hit the Team Total Under in 32 of their last 53 games at home (+7.75 Units / 12% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 66 of their last 118 games (+7.21 Units / 5% ROI)
  • The Houston Astros have covered the 1st Five Innings (F5) Run Line in 10 of their last 15 games (+5.21 Units / 31% ROI)
  • The Houston Astros have covered the Run Line in 52 of their last 100 games (+4.60 Units / 4% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 20-9 against the Run Line (+11.95 Units / 31.91% ROI).

  • 19-10 when betting on the Moneyline for +8.97 Units / 23.59% ROI
  • 16-11 when betting on the total runs Over for +3.95 Units / 12.36% ROI
  • 11-16 when betting on the total runs Under for -6.6 Units / -20.72% ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 10-19 against the Run Line (-8.6 Units / -25.6% ROI).

  • 10-19 when betting on the Moneyline for -14.25 Units / -36.03% ROI
  • 9-18 when betting on the total runs Over for -10.4 Units / -33.07% ROI
  • 18-9 when betting on the total runs Under for +8.05 Units / 24.85% ROI

Astros vs Guardians Home Run Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 +250 0.5 -300
Josh Naylor (CLE) 0.5 +375 0.5 -500
Yainer Diaz (HOU) 0.5 +400 0.5 -550
Jose Ramirez (CLE) 0.5 +425 0.5 -600
Jose Altuve (HOU) 0.5 +425 0.5 -600

Astros vs Guardians Total Hits Prop Bets Today

Over Under
Yainer Diaz (HOU) 0.5 -275 0.5 +200
Josh Naylor (CLE) 0.5 -250 0.5 +180
Jose Ramirez (CLE) 0.5 -250 0.5 +180
Jose Altuve (HOU) 0.5 -250 0.5 +185
Jeremy Pena (HOU) 0.5 -250 0.5 +185

Astros vs Guardians RBI Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 +120 0.5 -155
Yainer Diaz (HOU) 0.5 +130 0.5 -175
Josh Naylor (CLE) 0.5 +135 0.5 -185
Jose Ramirez (CLE) 0.5 +150 0.5 -200
Jeremy Pena (HOU) 0.5 +155 0.5 -210

Astros vs Guardians Strikeout Prop Bets Today

Over Under

Triston McKenzie has walked 9 of 45 batters (20%) when going through the lineup the first time in a game this season — 3rd highest in MLB among starting pitchers with at least 11 total IP; League Avg: 8% — second Percentile.

Triston McKenzie has allowed an OBP of just .239 (205 PA’s) when going through the lineup the third time in a game since the 2022 season — best in MLB among starting pitchers with at least 140 total IP; League Avg: .322 — 100th Percentile.

Triston McKenzie has walked 17 of 102 batters (17%) this season — 4th highest in MLB among starting pitchers with at least 11 total IP; League Avg: 8% — second Percentile.

Opponents have a groundball rate of just 31% (21/67) against Triston McKenzie this season — 7th lowest in MLB among starting pitchers with at least 11 total IP; League Avg: 43% — fourth Percentile.

Astros Starting Pitcher Stats & Trends

Justin Verlander has allowed a slugging percentage of just .266 (162 Total Bases / 610 ABs) vs left-handed batters since the 2022 season — best in MLB among starting pitchers with at least 140 total IP; League Avg: .401 — 100th Percentile.

Justin Verlander has allowed an OPS of just .503 (661 PA’s) vs left-handed batters since the 2022 season — best in MLB among starting pitchers with at least 140 total IP; League Avg: .711 — 100th Percentile.

Justin Verlander has allowed an OPS of just .575 (1,376 PA’s) since the 2022 season — best in MLB among starting pitchers with at least 140 total IP; League Avg: .712 — 100th Percentile.

Opponents are hitting just .050 (1-for-20) against Justin Verlander with two-strikes over the last 14 days — 3rd best among AL Starters over the last two weeks; League Avg: .165 — 96th Percentile.

Guardians Keys to the Game vs. the Astros

The Guardians are 11-139 (.073) when trailing entering the 9th inning since the 2022 season — tied for 4th best in MLB; League Avg: .050.

The Guardians are 12-68 (.150) when trailing entering the 8th inning since the 2023 season — 5th best in MLB; League Avg: .103.

The Guardians are just 10-17 (.370) when tied entering the 7th inning since the 2023 season — 2nd lowest in MLB; League Avg: .500.

The Guardians are 35-121 (.224) when trailing entering the 7th inning since the 2022 season — best in MLB; League Avg: .133.

Astros Keys to the Game vs. the Guardians

The Astros are 16-15 (.516) after a loss as underdogs since the 2022 season — 3rd best in MLB; League Avg: .410.

The Astros are 118-85 (.581) after a win since the 2022 season — 4th best in MLB; League Avg: .512.

The Astros are 63-43 (.594) after a road win since the 2022 season — 2nd best in MLB; League Avg: .491.

The Astros are 146-21 (.874) when scoring 5 or more runs since the 2022 season — best in MLB; League Avg: .794.

Guardians hitters have just 1,744 strikeouts in 9,577 PA’s (18%) against RHP since the 2022 season — best in MLB; League Avg: 23%.

Guardians hitters have just 2,486 strikeouts in 13,376 PA’s (19%) since the 2022 season — best in MLB; League Avg: 23%.

Guardians hitters are slugging just .363 against LHP since the 2022 season — lowest in MLB; League Avg: .407.

Guardians hitters have put just 34% of balls in play to the left side of the field since last season — lowest in MLB; League Avg: 39%.

Astros hitters have just 704 strikeouts in 3,991 PA’s (18%) against LHP since the 2022 season — best in MLB; League Avg: 22%.

Astros hitters are slugging .465 against LHP since last season — 2nd best in MLB; League Avg: .414.

Astros hitters have an OPS of .927 (566 PA’s) in lefty-lefty matchups since last season — best in MLB; League Avg: .687.

Astros hitters have just 383 strikeouts in 2,141 PA’s (18%) against LHP since last season — best in MLB; League Avg: 22%.

Guardians pitchers have a strikeout rate of 28% with runners in scoring position this season — best in MLB; League Avg: 21%.

Opponents have a miss rate of 29% against Guardians pitchers this season — best in MLB; League Avg: 25%.

Guardians pitchers have a strikeout rate of 46% with two-strikes this season — 3rd best in MLB; League Avg: 42%.

Opponents have a groundball rate of just 41% against Guardians pitchers since last season — 5th lowest in MLB; League Avg: 43%.

Astros pitchers have an ERA of 3.54 (3145.2 IP) since the 2022 season — 2nd best in MLB; League Avg: 4.14.

Astros pitchers have thrown at least two strikes in their first three pitches to 58% of opposing batters this season — 2nd lowest in MLB; League Avg: 64%.

Astros pitchers have a strikeout rate of 25% since the 2022 season — 2nd best in MLB; League Avg: 23%.

Opponents have a miss rate of 28% against Astros pitchers since the 2022 season — 2nd best in MLB; League Avg: 26%.

Astros vs. Guardians Injuries Tonight That May Affect Prop Bets 

  • Grae Kessinger (Houston Astros): Hamstring, Day-To-Day
  • Justin Verlander (Houston Astros): Shoulder, 15-Day IL
  • Penn Murfee (Houston Astros): Elbow, 15-Day IL
  • Kendall Graveman (Houston Astros): Shoulder, 60-Day IL
  • Jose Abreu (Houston Astros): Hand, Day-To-Day
  • Jose Urquidy (Houston Astros): Forearm, 15-Day IL
  • Oliver Ortega (Houston Astros): Elbow, 15-Day IL
  • Lance McCullers (Houston Astros): Forearm, 60-Day IL
  • Bennett Sousa (Houston Astros): Shoulder, 15-Day IL
  • Forrest Whitley (Houston Astros): Finger, 7-Day IL
  • Shawn Dubin (Houston Astros): Forearm, 15-Day IL
  • Daniel Espino (Cleveland Guardians): Shoulder, Out
  • Gavin Williams (Cleveland Guardians): Elbow, 15-Day IL
  • Ben Lively (Cleveland Guardians): Illness, 15-Day IL
  • Luis Ortiz (Cleveland Guardians): Ankle, 15-Day IL
  • Xzavion Curry (Cleveland Guardians): Illness, 15-Day IL
  • Joey Cantillo (Cleveland Guardians): Hamstring, Out
  • Angel Martinez (Cleveland Guardians): Foot, 10-Day IL
  • Sam Hentges (Cleveland Guardians): Finger, 15-Day IL
  • Trevor Stephan (Cleveland Guardians): Elbow, 60-Day IL
  • George Valera (Cleveland Guardians): Hamstring, Out
  • James Karinchak (Cleveland Guardians): Shoulder, 60-Day IL

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.