- The Orioles are -150 favorites vs the Cardinals
- Orioles vs Cardinals Over / Under today: 9 Runs
- Orioles / Cardinals TV Channel: MAS2 | BSMW | MLBN
The Baltimore Orioles () visit Busch Stadium to take on the St. Louis Cardinals () on Wednesday, May 22, 2024. First pitch is scheduled for 2:15pm EDT in St. Louis, MO.
This season, the Orioles are 29-16 against the spread (ATS), while the Cardinals are 23-24 ATS.
Orioles vs Cardinals Starting Pitchers Today:
- Orioles starting pitcher: John Means 2-0, 3.12 ERA
- Cardinals starting pitcher: Kyle Gibson 3-2, 4.09 ERA
Orioles vs. Cardinals Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Orioles | O | ||
| Cardinals | U |
Orioles vs Cardinals Prediction for Today’s Game
Based on recent trends the model predicts the Orioles will win Wednesday‘s MLB game with 58.1% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
Bet now on Orioles vs Cardinals and all games with BetMGM
We’ve highlighted some favorite MLB player prop bets for Orioles players for Wednesday‘s game, looking at profitable historical betting trends:
Best Orioles Player Prop Bets Today:
- Gunnar Henderson has hit the Home Runs Over in 15 of his last 39 games (+37.45 Units / 96% ROI)
- Jorge Mateo has hit the Runs Over in 14 of his last 18 games (+18.35 Units / 102% ROI)
- Gunnar Henderson has hit the RBIs Over in 22 of his last 44 games (+16.20 Units / 37% ROI)
- Anthony Santander has hit the Singles Under in 21 of his last 26 games (+13.15 Units / 34% ROI)
- Ryan O’Hearn has hit the Hits Over in 14 of his last 15 games (+13.00 Units / 39% ROI)
And here are some favorite MLB player prop bets for Cardinals players for Wednesday‘s game, looking at profitable historical betting trends:
Best Cardinals Player Prop Best Bets Today:
- Alec Burleson has hit the Home Runs Over in 5 of his last 18 games (+23.80 Units / 132% ROI)
- Nolan Arenado has hit the Singles Over in 28 of his last 44 games (+11.85 Units / 25% ROI)
- Nolan Arenado has hit the Hits Over in 33 of his last 44 games (+11.30 Units / 12% ROI)
- Brendan Donovan has hit the Runs Under in 26 of his last 37 games (+10.95 Units / 21% ROI)
- Paul Goldschmidt has hit the Total Bases Under in 28 of his last 44 games (+9.15 Units / 14% ROI)
Orioles Best Bets Today:
- The Baltimore Orioles have covered the 1st Five Innings (F5) Run Line in 21 of their last 30 games (+11.45 Units / 32% ROI)
- The Baltimore Orioles have hit the 1st Five Innings (F5) Moneyline in 20 of their last 30 games (+8.35 Units / 19% ROI)
- The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Under in 11 of their last 17 away games (+5.15 Units / 26% ROI)
- The Baltimore Orioles have hit the Moneyline in 11 of their last 15 away games (+5.10 Units / 27% ROI)
- The Baltimore Orioles have covered the Run Line in 19 of their last 36 games (+4.95 Units / 11% ROI)
Cardinals Best Bets Today:
- The St. Louis Cardinals have hit the Game Total Over in 11 of their last 12 games (+9.80 Units / 73% ROI)
- The St. Louis Cardinals have hit the Team Total Under in 24 of their last 39 games (+7.25 Units / 15% ROI)
- The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 20 of their last 33 games (+5.25 Units / 13% ROI)
- The St. Louis Cardinals have hit the Moneyline in 6 of their last 8 games (+4.10 Units / 45% ROI)
- The St. Louis Cardinals have covered the Run Line in 5 of their last 8 games (+2.60 Units / 25% ROI)
Orioles Against the Spread (ATS) Record
Against the spread this season, the Orioles are 23-22 against the Run Line (+4.8 Units / 9.12% ROI).
- 29-16 when betting on the Moneyline for +4.4 Units / 6.8% ROI
- 23-18 when betting on the total runs Over for +3.35 Units / 6.79% ROI
- 18-23 when betting on the total runs Under for -7.55 Units / -15.19% ROI
Cardinals Against the Spread (ATS) Record
Against the spread this season, the Cardinals are 23-24 against the Run Line (-2.95 Units / -4.75% ROI).
- 21-26 when betting on the Moneyline for -8.25 Units / -14.28% ROI
- 22-23 when betting on the total runs Over for -3.6 Units / -6.9% ROI
- 23-22 when betting on the total runs Under for -0.9 Units / -1.75% ROI
Cardinals vs Orioles Home Run Prop Bets Today
| Over | Under | |
|---|---|---|
| Gunnar Henderson (BAL) | 0.5 +240 | 0.5 -300 |
| Anthony Santander (BAL) | 0.5 +260 | 0.5 -350 |
| Ryan O'Hearn (BAL) | 0.5 +360 | 0.5 -500 |
| Jordan Westburg (BAL) | 0.5 +400 | 0.5 -550 |
| Adley Rutschman (BAL) | 0.5 +400 | 0.5 -550 |
Cardinals vs Orioles Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Ryan Mountcastle (BAL) | 0.5 -275 | 0.5 +195 |
| Jordan Westburg (BAL) | 0.5 -225 | 0.5 +170 |
| Lars Nootbaar (STL) | 0.5 -225 | 0.5 +165 |
| Cedric Mullins (BAL) | 0.5 -210 | 0.5 +160 |
| Colton Cowser (BAL) | 0.5 -210 | 0.5 +155 |
Cardinals vs Orioles RBI Prop Bets Today
| Over | Under | |
|---|---|---|
| Gunnar Henderson (BAL) | 0.5 +105 | 0.5 -135 |
| Anthony Santander (BAL) | 0.5 +115 | 0.5 -150 |
| Adley Rutschman (BAL) | 0.5 +130 | 0.5 -165 |
| Ryan O'Hearn (BAL) | 0.5 +135 | 0.5 -185 |
| Ryan Mountcastle (BAL) | 0.5 +140 | 0.5 -190 |
Cardinals vs Orioles Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Lance Lynn (STL) | 4.5 -120 | 4.5 -110 |
| Kyle Bradish (BAL) | 5.5 +120 | 5.5 -155 |
Orioles Starting Pitcher Stats & Trends
Right-handed hitters have a groundball rate of just 17% (5/30) against John Means — lowest in MLB over the last two weeks; League Avg: 43% — first Percentile.
John Means has not allowed a walk in his last 87 PAs against a RHH dating back to September 23rd, 2023 — Jake Irvin has the longest active streak at 92.
John Means’ has 7 strikeouts and no walks — tied for best in MLB K:BB ratio over the last two weeks; League Avg: 3.3 — 100th Percentile.
Right-handed hitters have a groundball rate of just 17% (5/30) against John Means over the last 14 days — 3rd lowest among AL Starters over the last two weeks; League Avg: 41% — fifth Percentile.
Cardinals Starting Pitcher Stats & Trends
Kyle Gibson has a strike rate of just 54% (115/214) with runners in scoring position this season — lowest among qualified SPs in MLB; League Avg: 65% — first Percentile.
Kyle Gibson has a strike rate of just 56% (264/473) vs left-handed batters this season — lowest among qualified SPs in MLB; League Avg: 64% — first Percentile.
Kyle Gibson has thrown at least two strikes in his first three pitches to 36% (19/52) of opposing batters this month (3 games) — lowest among qualified SPs in MLB; League Avg: 66% — 0 Percentile.
Kyle Gibson has a strike rate of just 59% (496/843) this season — lowest among qualified SPs in MLB; League Avg: 65% — first Percentile.
Orioles Keys to the Game vs. the Cardinals
The Orioles are 55-41 (.573) after a loss as underdogs since the 2022 season — 2nd best in MLB; League Avg: .412.
The Orioles are 18-6 (.750) when tied entering the 7th inning since the 2023 season — best in MLB; League Avg: .500.
The Orioles are 26-15 (.634) when tied entering the 7th inning since the 2022 season — best in MLB; League Avg: .500.
The Orioles are 29-21 (.580) after a win as underdogs since the 2023 season — 3rd best in MLB; League Avg: .425.
Cardinals Keys to the Game vs. the Orioles
The Cardinals are 28-12 (.700) when tied entering the 8th inning since the 2022 season — best in MLB; League Avg: .500.
The Cardinals are just 17-28 (.378) after a win as favorites since the 2023 season — 3rd lowest in MLB; League Avg: .575.
The Cardinals are just 44-58 (.431) at home since the 2023 season — 5th lowest in MLB; League Avg: .520.
The Cardinals are just 5-100 (.048) when trailing entering the 8th inning since the 2023 season — 3rd lowest in MLB; League Avg: .102.
Orioles Hitting Stats & Trends
Orioles hitters are slugging .505 against LHP this season — best in MLB; League Avg: .387.
Orioles hitters have an OPS of .845 (534 PA’s) against LHP this season — best in MLB; League Avg: .699.
Orioles hitters have 57 extra-base hits out of 136 total hits (42%) against LHP this season — 2nd best in MLB; League Avg: 33%.
Orioles hitters have an OPS of .960 (154 PA’s) against LHP this month (13 games) — best in MLB; League Avg: .693.
Cardinals Hitting Stats & Trends
The Cardinals have not scored first in any of their games against division opponents this season — lowest in MLB; League Avg: 50%.
The Cardinals are batting just .203 against LHP this season — 2nd lowest in MLB; League Avg: .244.
The Cardinals are batting just .235 against LHP since last season — tied for 2nd lowest in MLB; League Avg: .252.
The Cardinals are batting just .205 with two outs this season — tied for 2nd lowest in MLB; League Avg: .229.
Orioles Pitching Stats & Trends
The Orioles won 53% of road games in which their opponents scored first in the 2023 season — highest in MLB; League Avg: 29%.
The Orioles have won 51% of road games in which their opponents scored first since last season — highest in MLB; League Avg: 29%.
Orioles pitchers have won 41% of games in which they have allowed their opponent to score in three different innings since last season — 2nd highest in MLB; League Avg: 28%.
Orioles pitchers have won 43% of games in which they have allowed their opponent to score in three different innings on the road since last season — highest in MLB; League Avg: 26%.
Cardinals Pitching Stats & Trends
Cardinals pitchers have a strikeout rate of just 20% since the 2022 season — 3rd lowest in MLB; League Avg: 23%.
Cardinals pitchers have walked 119 of 1,847 batters (6%) when facing the leadoff batter in the inning since last season — tied for 2nd best in MLB; League Avg: 8%.
Opponents have a miss rate of just 23% against Cardinals pitchers since last season — 3rd lowest in MLB; League Avg: 26%.
Cardinals pitchers have a strikeout rate of just 39% with two-strikes since last season — 3rd lowest in MLB; League Avg: 42%.
Cardinals vs. Orioles Injuries Tonight That May Affect Prop Bets
- Dylan Carlson (St. Louis Cardinals): Shoulder, 10-Day IL
- Keynan Middleton (St. Louis Cardinals): Forearm, 15-Day IL
- Lars Nootbaar (St. Louis Cardinals): Ribs, 10-Day IL
- Drew Rom (St. Louis Cardinals): Biceps, 15-Day IL
- Sonny Gray (St. Louis Cardinals): Hamstring, 15-Day IL
- Riley O’Brien (St. Louis Cardinals): Forearm, 15-Day IL
- Tommy Edman (St. Louis Cardinals): Wrist, 10-Day IL
- Packy Naughton (St. Louis Cardinals): Elbow, Out
- Felix Bautista (Baltimore Orioles): Elbow, 60-Day IL
- Terrin Vavra (Baltimore Orioles): Shoulder, Day-To-Day
- John Means (Baltimore Orioles): Forearm, 15-Day IL
- Kyle Bradish (Baltimore Orioles): Elbow, 15-Day IL
- Cionel Perez (Baltimore Orioles): Oblique, 15-Day IL
Bet now on Orioles vs Cardinals and all games with BetMGM
Bet on MLB Odds at BetMGM
Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.
