Padres vs Guardians Prediction, Odds & Player Prop Bets Today – MLB, Jul 21

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Cleveland Guardians' Josh Naylor runs the base path during a spring training baseball game against the San Diego Padres, Monday, Feb. 26, 2024, in Peoria, Ariz.
(AP Photo/Lindsey Wasson)
BetMGM Betting @BETMGM Jul 21, 2024, 11:01 AM
  • The Guardians are -120 favorites vs the Padres
  • Padres vs Guardians Over / Under today: 8 Runs
  • Padres / Guardians TV Channel: BSGL | PDTV | ESPN+

The San Diego Padres (+100) visit Progressive Field to take on the Cleveland Guardians (-120) on Sunday, July 21, 2024. First pitch is scheduled for 1:40pm EDT in Cleveland, OH.

This season, the Padres are 51-50 against the spread (ATS), while the Guardians are 49-48 ATS.

Padres vs Guardians Starting Pitchers Today:

  • Padres starting pitcher: Michael King 7-6, 3.43 ERA
  • Guardians starting pitcher: Ben Lively 8-5, 3.60 ERA

Padres vs. Guardians Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Padres+1.5 -210O 8 -110+100
Guardians -1.5 +160U 8 -110-120

Padres vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Padres will win Sunday‘s MLB game with 54.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Padres players for Sunday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Bets Today:

  • Jackson Merrill has hit the Home Runs Over in 6 of his last 14 games (+37.30 Units / 266% ROI)
  • Jackson Merrill has hit the RBIs Over in 11 of his last 18 games (+13.55 Units / 75% ROI)
  • Jurickson Profar has hit the Hits Over in 20 of his last 24 away games (+11.50 Units / 22% ROI)
  • Jurickson Profar has hit the Singles Over in 18 of his last 24 away games (+11.05 Units / 39% ROI)
  • Jurickson Profar has hit the Hits Runs and RBIs Over in 14 of his last 17 games (+10.80 Units / 55% ROI)

And here are some favorite MLB player prop bets for Guardians players for Sunday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Best Bets Today:

  • Steven Kwan has hit the Home Runs Over in 4 of his last 16 games (+37.00 Units / 231% ROI)
  • Jose Ramirez has hit the Runs Over in 32 of his last 44 games (+19.65 Units / 40% ROI)
  • Jose Ramirez has hit the RBIs Over in 26 of his last 43 games (+15.45 Units / 35% ROI)
  • Steven Kwan has hit the Hits Runs and RBIs Over in 16 of his last 18 games (+13.30 Units / 50% ROI)
  • Andres Gimenez has hit the Hits Under in 11 of his last 18 games (+11.40 Units / 55% ROI)
  • The San Diego Padres have covered the Run Line in 30 of their last 47 away games (+13.10 Units / 21% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in 13 of their last 18 away games (+8.80 Units / 45% ROI)
  • The San Diego Padres have hit the Game Total Under in 13 of their last 18 away games (+7.35 Units / 37% ROI)
  • The San Diego Padres have hit the Moneyline in 6 of their last 9 away games (+4.25 Units / 45% ROI)
  • The Cleveland Guardians have hit the Moneyline in 29 of their last 38 games at home (+14.80 Units / 27% ROI)
  • The Cleveland Guardians have hit the Team Total Over in 26 of their last 38 games at home (+13.10 Units / 30% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 57 of their last 97 games (+12.70 Units / 11% ROI)
  • The Cleveland Guardians have covered the Run Line in 21 of their last 39 games at home (+11.25 Units / 27% ROI)
  • The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 24 of their last 38 games at home (+10.05 Units / 23% ROI)

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 50-51 against the Run Line (+0.25 Units / 0.2% ROI).

  • 51-50 when betting on the Moneyline for -8.55 Units / -6.56% ROI
  • 53-47 when betting on the total runs Over for +1.7 Units / 1.54% ROI
  • 47-53 when betting on the total runs Under for -11.7 Units / -10.44% ROI

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 49-48 against the Run Line (+4.55 Units / 3.87% ROI).

  • 59-38 when betting on the Moneyline for +13.77 Units / 10.81% ROI
  • 47-44 when betting on the total runs Over for -1.65 Units / -1.54% ROI
  • 44-47 when betting on the total runs Under for -7.55 Units / -7.12% ROI

Guardians vs Padres Home Run Prop Bets Today

Over Under
Manny Machado (SD) 0.5 +475 0.5 -650
Josh Naylor (CLE) 0.5 +500 0.5 -750
Jose Ramirez (CLE) 0.5 +525 0.5 -750
Jake Cronenworth (SD) 0.5 +600 0.5 -900
Kyle Higashioka (SD) 0.5 +625 0.5 -1000

Guardians vs Padres Total Hits Prop Bets Today

Over Under
Manny Machado (SD) 0.5 -275 0.5 +195
Josh Naylor (CLE) 0.5 -250 0.5 +175
Jose Ramirez (CLE) 0.5 -250 0.5 +175
Xander Bogaerts (SD) 0.5 -250 0.5 +185
Jurickson Profar (SD) 0.5 -225 0.5 +160

Guardians vs Padres RBI Prop Bets Today

Over Under
Manny Machado (SD) 0.5 +135 0.5 -175
Josh Naylor (CLE) 0.5 +145 0.5 -190
Jose Ramirez (CLE) 0.5 +150 0.5 -200
Jake Cronenworth (SD) 0.5 +160 0.5 -210
David Peralta (SD) 0.5 +165 0.5 -225

Guardians vs Padres Strikeout Prop Bets Today

Over Under
Ben Lively (CLE) 3.5 -110 3.5 -120

Michael King has allowed an average Exit Velocity of just 82.3 MPH on non-fastballs since the 2022 season (282 balls in play) — best in MLB among starting pitchers with at least 163 total IP; League Avg: 87.1

Michael King has a strikeout rate of 33% (60 SO in 180 PAs) when going through the lineup the first time in a game this season — tied for 4th best among qualified SPs in MLB; League Avg: 25% — 95th Percentile.

Michael King has struck out 32% (73/226) of right-handed batters he faced this season — 4th best among qualified SPs in MLB; League Avg: 24% — 95th Percentile.

Michael King has allowed an average Exit Velocity of just 86.3 MPH since the 2022 season (606 balls in play) — tied for 4th best in MLB among starting pitchers with at least 163 total IP; League Avg: 88.9

Guardians Starting Pitcher Stats & Trends

Opponents are hitting just .059 (1-for-17) against Ben Lively when going through the lineup the first time in a game in his last two starts — tied for 4th best in MLB over the last two weeks; League Avg: .229 — 96th Percentile.

Ben Lively has allowed a slugging percentage of .630 (92 Total Bases / 146 ABs) on inside fastballs since the 2022 season — 3rd highest in MLB among starting pitchers with at least 168 total IP; League Avg: .430 — second Percentile.

Ben Lively has allowed a slugging percentage of .630 (92 Total Bases / 146 ABs) on inside fastballs since last season — 3rd highest in MLB among starting pitchers with at least 103 total IP; League Avg: .434 — second Percentile.

Opponents have a line drive rate of just 8% (4/48) against Ben Lively this month (3 games) — lowest among qualified SPs in MLB; League Avg: 24% — 100th Percentile.

Padres Keys to the Game vs. the Guardians

The Padres are just 32-112 (.222) when scoring 4 or fewer runs since the 2023 season — 5th lowest in MLB; League Avg: .270.

The Padres are just 0-45 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .056.

The Padres are just 12-45 (.211) when scoring 4 or fewer runs this season — 5th lowest in MLB; League Avg: .275.

The Padres are just 10-163 (.058) when trailing entering the 8th inning since the 2022 season — 4th lowest in MLB; League Avg: .095.

Guardians Keys to the Game vs. the Padres

The Guardians are 31-11 (.738) at home this season — best in MLB; League Avg: .531.

The Guardians are 18-14 (.562) when allowing 2 or more home runs this season — best in MLB; League Avg: .301.

The Guardians are 13-3 (.812) after a home loss this season — 2nd best in MLB; League Avg: .547.

The Guardians are 10-14 (.417) when allowing 10 or more hits this season — 2nd best in MLB; League Avg: .245.

The Padres are batting .316 when facing the starting pitcher for the 3rd time in a game this season — best in MLB; League Avg: .265.

Padres hitters have an OBP of .378 (459 PA’s) when facing the starting pitcher for the 3rd time in a game this season — best in MLB; League Avg: .329.

The Padres are batting .275 on the road this season — best in MLB; League Avg: .241.

Padres hitters have just 945 strikeouts in 4,689 PA’s (20%) against LHP since the 2022 season — 5th best in MLB; League Avg: 22%.

Guardians hitters have put just 34% of balls in play to the left side of the field since last season — lowest in MLB; League Avg: 38%.

Guardians hitters have just 2,070 strikeouts in 11,326 PA’s (18%) against RHP since the 2022 season — best in MLB; League Avg: 23%.

Guardians hitters have missed on just 22% of swings since the 2022 season — best in MLB; League Avg: 26%.

Guardians hitters have put 41% of balls in play to the right side of the field since last season — highest in MLB; League Avg: 37%.

Padres pitchers allowed an average Exit Velocity of 87.9 MPH (3,921 batted balls) in the 2023 season — best in MLB; League Avg: 89.0.

The Padres pitchers allowed an average Exit Velocity of just 87.9 MPH in the 2023 season (3,921 balls in play) — best in MLB; League Avg: 89.0

Padres pitchers have a strikeout rate of 24% this season — 5th best in MLB; League Avg: 22%.

Opponents have a groundball rate of just 35% against Padres pitchers over the last 14 days — lowest in MLB; League Avg: 44%.

Opponents have a groundball batting average of just .198 against Guardians pitchers with runners on base this season — best in MLB; League Avg: .259.

Guardians pitchers have won 47% of games in which they have allowed their opponent to score in three different innings this season — highest in MLB; League Avg: 26%.

Guardians pitchers have a strikeout rate of 44% with two-strikes this season — 2nd best in MLB; League Avg: 42%.

The Guardians have allowed 0.75 runs per game (73/97) in late innings this season — best in MLB; League Avg: 1.28.

Guardians vs. Padres Injuries Tonight That May Affect Prop Bets 

  • Daniel Espino (Cleveland Guardians): Shoulder, Out
  • Gavin Williams (Cleveland Guardians): Elbow, 15-Day IL
  • Ben Lively (Cleveland Guardians): Illness, 15-Day IL
  • Luis Ortiz (Cleveland Guardians): Ankle, 15-Day IL
  • Xzavion Curry (Cleveland Guardians): Illness, 15-Day IL
  • Joey Cantillo (Cleveland Guardians): Hamstring, Out
  • Angel Martinez (Cleveland Guardians): Foot, 10-Day IL
  • Sam Hentges (Cleveland Guardians): Finger, 15-Day IL
  • Trevor Stephan (Cleveland Guardians): Elbow, 60-Day IL
  • George Valera (Cleveland Guardians): Hamstring, Out
  • James Karinchak (Cleveland Guardians): Shoulder, 60-Day IL
  • Glenn Otto (San Diego Padres): Shoulder, 15-Day IL
  • Reiss Knehr (San Diego Padres): Elbow, Out
  • Drew Carlton (San Diego Padres): Elbow, Out
  • Luis Patino (San Diego Padres): Elbow, 15-Day IL
  • Tucupita Marcano (San Diego Padres): Knee, 10-Day IL

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.