76ers vs. Celtics Prediction & Odds for NBA Christmas Day

In the third game of this year’s NBA slate on Christmas Day, the Boston Celtics will host the Philadelphia 76ers at 5 p.m. ET on Wednesday in the TD Garden.

The Celtics are nearly double-digit favorites in a matchup where they should flex their muscles as the best team in basketball. But will the 76ers keep things close on Wednesday?

Here is a look at the latest 76ers vs. Celtics NBA odds and my best bet for Christmas Day:

76ers vs. Celtics Odds, Dec. 25

• Point spread: Celtics -10.5
• Moneyline: 76ers +350/Celtics -450
• Total: 221.5

76ers vs. Celtics Prediction – Friday, Dec. 25

Based on the latest NBA betting lines, my favorite 76ers vs. Celtics prediction is over 10.5 points (-120) for Payton Pritchard in a game where the Boston reserve should get plenty of playing time.

Oddsmakers expect the Celtics to roll on Wednesday, listing them as double-digit favorites. That could give Pritchard more minutes in the second half.

He played just 21 minutes in Monday’s loss to the Orlando Magic. Pritchard has finished in single digits in back-to-back games.

But Pritchard has been my favorite Sixth Man of the Year pick since he was 100/1 in the preseason for a reason. He’s averaging 15.7 points per game as the favorite for the award, clearing this prop in nine of his past 12 games.

I like Pritchard’s chances of scoring at least 11 in a marquee matchup.

Prediction: Payton Pritchard Over 10.5 Points (-120)

76ers’ Record on Christmas Day

The 76ers are 19-15 all-time in 34 games on Christmas Day.

Philadelphia suffered a 119-113 loss to Miami last year.

Celtics’ Record on Christmas Day

The Celtics have played 37 games on Christmas Day, posting a 17-20 overall record.

Boston has won back-to-back games on this holiday.