Louisville vs Duke Prediction, Odds & Best Bets Today – NCAAB, Mar. 15

Duke head coach Jon Scheyer watches from the sideline against North Carolina State during the first half of an NCAA college basketball game in Raleigh, N.C., Wednesday, Jan. 4, 2023.
(AP Photo/Karl B DeBlaker)
  • Duke is a -6.5 point favorite vs Louisville
  • Total (Over/Under): 147.5 points
  • Louisville / Duke TV channel: ESPN

The Louisville Cardinals visit Spectrum Center to take on the Duke Blue Devils on Mar. 15. Tip off is scheduled for 8:30pm EDT in Charlotte, NC, NC, USA.

Duke is the betting favorite in this game, with the spread sitting at -6.5 (-105).

The Louisville vs. Duke Over/Under is 147.5 total points.

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Louisville vs. Duke Odds, Spread, Over/Under

SpreadTotal (O/U)Moneyline
Louisville+6.5 -115O 147.5 -115+200
Duke -6.5 -105U 147.5 -105-250

Louisville vs Duke Prediction for Today:

The winning team model predicts Duke will win this college basketball game with 78.5% confidence, based on game simulations, player injuries, key player performances and recent matchups.

Louisville vs Duke Spread Prediction:

Based on recent against-the-spread trends, the spread model predicts Louisville will cover the spread with 55.1% confidence for today’s game.


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  • Louisville has hit the Moneyline in 26 of their last 31 games (+17.85 Units / 6% ROI)
  • Louisville has hit the 1H Moneyline in 21 of their last 22 games (+17.65 Units / 21% ROI)
  • Louisville have covered the 1H Spread in 17 of their last 20 games (+14.70 Units / 64% ROI)
  • Louisville have covered the Spread in 16 of their last 23 games (+8.30 Units / 33% ROI)
  • Louisville has hit the Game Total Under in 21 of their last 33 games (+7.95 Units / 22% ROI)
  • Duke has hit the Moneyline in 33 of their last 37 games (+23.70 Units / 2% ROI)
  • Duke have covered the Spread in 24 of their last 37 games (+9.70 Units / 24% ROI)
  • Duke have covered the 1H Spread in 23 of their last 37 games (+6.80 Units / 16% ROI)
  • Duke has hit the 1H Game Total Over in 21 of their last 37 games (+2.50 Units / 6% ROI)

Louisville Basketball Against the Spread Record (ATS)

Louisville has a 20-13 record against the spread this college basketball season (+5.7 Units / 15.66% ROI).

  • 27-6 when betting on the Moneyline for +17.35 Units / 5% ROI
  • 12-21 when betting the Over for -11.2 Units / -30.68% ROI
  • 21-12 when betting the Under for +7.95 Units / 21.99% ROI

Duke Basketball Against the Spread Record (ATS)

Duke has a 21-12 record against the spread this college basketball season (+7.8 Units / 21.49% ROI).

  • 30-3 when betting on the Moneyline for +22.95 Units / 1.63% ROI
  • 17-16 when betting the Over for -0.6 Units / -1.65% ROI
  • 16-17 when betting the Under for -2.7 Units / -7.44% ROI

Louisville Offensive Stats & Trends:

Louisville has a 43% free throw rate (935 free throw attempts/2,189 field goal attempts) at home since the start of the 2023-24 season — highest among ACC Teams; League Avg: 34%

Louisville shot 28% from three (77/275) in the first half last season — lowest among ACC Teams; League Avg: 35%

Louisville averaged 5.0 assists per game (154 assists/31 games) in the first half last season — lowest among ACC Teams; League Avg: 6.8

Louisville is shooting 30% from three (266/883) at home since the start of the 2023-24 season — lowest among ACC Teams; League Avg: 35%

Duke Offensive Stats & Trends:

Duke has an assist to turnover ratio of 1.8 (545 assists/ 303 TOs) this season — best among ACC Teams; League Avg: 1.2

Duke has an assist to turnover ratio of 1.8 (545 assists/ 303 TOs) this season — tied for 3rd best among Division 1 Teams; League Avg: 1.2

Duke has an assist to turnover ratio of 1.9 (290 assists/ 152 TOs) in the first half this season — best among ACC Teams; League Avg: 1.2

Duke has an assist to turnover ratio of 1.7 (1,086 assists/ 645 TOs) since the start of the 2023-24 season — tied for 4th best among Division 1 Teams; League Avg: 1.2

Louisville Defensive Stats & Trends:

Louisville has averaged 26.3 defensive rebounds per game (843 rebounds/32 games) this season — tied for 33rd best among Division 1 Teams; League Avg: 24.1

Louisville allowed an average of 1.40 points per shot (1,958 points/1,397 shots) last season — 5th highest among Power Conference defenses; League Avg: 1.28

Louisville allowed opponents to shoot 48% (872/1,827) last season — 4th highest among Division 1 Teams; League Avg: 44%

Louisville allowed opponents to shoot 37% from three (266/714) last season — tied for 5th highest among Division 1 Teams; League Avg: 34%

Duke Defensive Stats & Trends:

Duke has allowed an average of 1.07 points per shot (1,972 points/1,844 shots) this season — tied for 3rd best among Division 1 Teams; League Avg: 1.24

Duke has averaged 27.6 defensive rebounds per game (882 rebounds/32 games) this season — 10th best among Division 1 Teams; League Avg: 24.1

Duke has allowed an average of 1.10 points per shot (1,023 points/929 shots) in the second half this season — best among ACC Teams; League Avg: 1.33

Duke has averaged 26.7 defensive rebounds per game (1,788 rebounds/67 games) since the start of the 2023-24 season — tied for 22nd best among Division 1 Teams; League Avg: 24.3


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