NFL Betting Lines Week 13: Biggest NFL Underdogs This Week

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Indianapolis Colts quarterback Matt Ryan warms up before a preseason NFL football game against the Buffalo Bills in Orchard Park, N.Y., Saturday, Aug. 13, 2022.
(AP Photo/Adrian Kraus)
BetMGM Staff @BETMGM Nov 29, 2022, 8:05 AM
  • Below are the biggest NFL underdogs this week.

With so much parity in the NFL, the phrase “Any Given Sunday” applies on the gridiron with upsets every week. When betting on the NFL, this is always something to consider.

Below are the biggest underdogs of the week.

NFL Betting Lines Week 13: NFL Underdogs in Week 13

Rank Matchup Favorite Underdog
1 Indianapolis Colts vs. Dallas Cowboys Cowboys (-9.5) Colts (+9.5)
2 Denver Broncos vs. Baltimore Ravens Ravens (-8) Broncos (+8)
3 Cleveland Browns vs. Houston Texans Browns (-7) Texans (+7)
4. (Tie) Buffalo Bills vs. New England Patriots Bills (-5.5) Patriots (+5.5)
4. (Tie) Tennessee Titans vs. Philadelphia Eagles Eagles (-5.5) Titans (+5.5)
4. (Tie) Seattle Seahawks vs. Los Angeles Rams Seahawks (-5.5) Rams (+5.5)
7 New Orleans Saints vs. Tampa Bay Buccaneers Buccaneers (-4) Saints (+4)
8 Miami Dolphins vs. San Francisco 49ers 49ers (-3.5) Dolphins (+3.5)
9 New York Jets vs. Minnesota Vikings Vikings (-3) Jets (+3)
10. (Tie) Green Bay Packers vs. Chicago Bears Packers (-2.5) Bears (+2.5)
10. (Tie) Kansas City Chiefs vs. Cincinnati Bengals Chiefs (-2.5) Bengals (+2.5)
10. (Tie) Los Angeles Chargers vs. Las Vegas Raiders Chargers (-2.5) Raiders (+2.5)

1. Indianapolis Colts (+9.5) vs. Dallas Cowboys (-9.5)

More often than not, the Indianapolis Colts play up and down to their competition, so this game could be much closer than the spread suggests.

2. Denver Broncos (+8) vs. Baltimore Ravens (-8)

It’s been difficult to watch the Denver Broncos on offense, which explains why the Baltimore Ravens are listed as eight-point home favorites.

3. Cleveland Browns (-7) vs. Houston Texans (+7)

It will be interesting to see how much the Houston Texans get up for this game, knowing that their former signal caller Deshaun Watson will be making his first start for the Cleveland Browns.

4. (Tie) Buffalo Bills (-5.5) vs. New England Patriots (+5.5)

The New England Patriots have continued to be a force running the football, which should be their game plan when they host the Buffalo Bills (who’ve struggled in that department).

4. (Tie) Tennessee Titans (+5.5) vs. Philadelphia Eagles (-5.5)

With their ground game and defensive prowess, the Tennessee Titans will be a threat to upset the Philadelphia Eagles in Week 13, especially if they can control time of possession.

4. (Tie) Seattle Seahawks (-5.5) vs. Los Angeles Rams (+5.5)

It’s difficult to be confident in the Los Angeles Rams any week, but you should never count out a team with this much defensive talent in a divisional game.

7. New Orleans Saints (+4) vs. Tampa Bay Buccaneers (-4)

The New Orleans Saints notoriously play the Tampa Bay Buccaneers extremely tough, which should be no different when they try and get closer in the divisional race.

8. Miami Dolphins (+3.5) vs. San Francisco 49ers (-3.5)

There’s a lot to like about how the Miami Dolphins compare to the rest of the AFC, but they’ll get a massive challenge this weekend when they visit the San Francisco 49ers as 3.5-point underdogs.

9. New York Jets (+3) vs. Minnesota Vikings (-3)

With Mike White suiting up for the New York Jets at quarterback, there’s more to like about the team offensively, which has the potential to give the Minnesota Vikings problems.

10. (Tie) Green Bay Packers (-2.5) vs. Chicago Bears (+2.5)

The Chicago Bears have found an offensive rhythm and have a chance to prove that against their biggest rivals, the Green Bay Packers.

10. (Tie) Kansas City Chiefs (-2.5) vs. Cincinnati Bengals (+2.5)

After picking up a big victory in Week 12 against the Tennessee Titans, the Cincinnati Bengals will look to upset the Kansas City Chiefs for the second straight season.

10. (Tie) Los Angeles Chargers (-2.5) vs. Las Vegas Raiders (+2.5)

The Las Vegas Raiders exploded offensively in Week 12, but they’ll have a bigger test this week when they play host to Justin Herbert and the Los Angeles Chargers.

 

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Our BetMGM authors are sports experts, with a wealth of knowledge of the sports betting industry at all levels. Their coverage includes sports news across players, teams and coaches, providing betting previews and predictions, fun facts and more.

Our BetMGM authors are sports experts, with a wealth of knowledge of the sports betting industry at all levels. Their coverage includes sports news across players, teams and coaches, providing betting previews and predictions, fun facts and more.