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The Cardinals odds to win the World Series are +10000.
World Series Favorites
The Cardinals odds to win the NL pennant are +5000.
NL Pennant Favorites
The Cardinals NL Central champion odds are +900
NL Central Odds
The Cardinals odds to make the playoffs are +450. Their odds to miss the playoffs are -625.
The Los Angeles Angels (+120) visit Busch Stadium to take on the St. Louis Cardinals (-145) on Tuesday, April 1, 2025. First pitch is scheduled for 7:45pm EDT in St. Louis, MO. This season, the Angels Read More
The Los Angeles Angels (+125) visit Busch Stadium to take on the St. Louis Cardinals (-150) on Monday, March 31, 2025. First pitch is scheduled for 7:45pm EDT in St. Louis, MO. This season, the Angels Read More
The Minnesota Twins (-125) visit Busch Stadium to take on the St. Louis Cardinals (+105) on Sunday, March 30, 2025. First pitch is scheduled for 2:15pm EDT in St. Louis, MO. This season, the Twins are Read More
The Minnesota Twins (-120) visit Busch Stadium to take on the St. Louis Cardinals (+100) on Saturday, March 29, 2025. First pitch is scheduled for 2:15pm EDT in St. Louis, MO. This season, the Twins a Read More
Find out which MLB teams had the youngest and oldest Opening Day roster for the 2025 season. Read More
The Minnesota Twins (-115) visit Busch Stadium to take on the St. Louis Cardinals (-105) on Thursday, March 27, 2025. First pitch is scheduled for 4:15pm EDT in St. Louis, MO, USA. This preseason, the Read More
Best MLB teams for 2025. See power rankings for the top MLB teams this season, including the Dodgers, Yankees, Braves, Orioles, and Mets. Read More
Season betting previews and predictions for the Brewers, Cardinals, Cubs, Pirates, and Reds before the 2025 MLB season. Read More
Check out updated MLB odds, projected depth chart, and betting predictions for the St. Louis Cardinals ahead of the 2025 season. Read More
Run lines, over/under totals, moneylines, and more odds are available for each Cardinals game this season.
If you’re in Missouri and interested in odds for other teams, check out:
Will the Cardinals win the NL Central? Will they win the NL pennant? How many home runs will a certain player hit this season?
For example: If you bet $30 on the Cardinals (+600) to make the postseason, the bet would settle when St. Louis is eliminated or when they clinch a postseason berth.
The run line is baseball’s version of the spread. What’s the final scoring margin of the game?
For example: If you bet $50 on the Cardinals -1.5 (+220) against the Pittsburgh Pirates, St. Louis must win the game by at least two runs.
Alternatively, if you bet $10 on the Cardinals +1.5 (-130) against the Atlanta Braves, St. Louis must lose by one run (or win the game).
Will the Cardinals win the game?
For example: If you bet $75 on the Cardinals -170 against the Texas Rangers, St. Louis must win the game (in nine innings or extra innings).
How many combined runs will be scored by both teams in the matchup?
For example: If you bet $50 on over 8.5 (-105) in their game against the New York Mets, the teams must combine for at least nine runs.
Alternatively, if you bet $60 on under 8.5 (-115), the teams must combine for eight or fewer runs.
If the combined run total is the same as the over/under total, the bet is a push.
You can combine bets and other bets — baseball or another sport — into one parlay.
For example: If you bet $80 on a two-leg parlay with the Cardinals moneyline (-145) vs. the Boston Red Sox and over 8.5 (-110) in the Philadelphia Phillies-San Diego Padres game, both must hit for the bet to cash.
If one bet is a push, it’s eliminated from the parlay, and odds (and payout) are recalculated without that leg.
