Angels vs Astros Prediction, Odds & Player Prop Bets Today – MLB, May 22

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Houston Astros' Jose Altuve bats during the first inning of a baseball game against the Texas Rangers, Wednesday, July 26, 2023, in Houston.
(AP Photo/Kevin M. Cox)
BetMGM Betting @BETMGM May 22, 2024, 11:01 AM
  • The Astros are -200 favorites vs the Angels
  • Angels vs Astros Over / Under today: 8.5 Runs
  • Angels / Astros TV Channel: SCHN | BSW | MLBN

The Los Angeles Angels () visit Minute Maid Park to take on the Houston Astros () on Wednesday, May 22, 2024. First pitch is scheduled for 2:10pm EDT in Houston, TX.

This season, the Angels are 19-30 against the spread (ATS), while the Astros are 20-29 ATS.

Angels vs Astros Starting Pitchers Today:

  • Angels starting pitcher: Tyler Anderson 4-4, 2.72 ERA
  • Astros starting pitcher: Hunter Brown 1-4, 7.79 ERA

Angels vs. Astros Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Angels O
Astros U

Angels vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Wednesday‘s MLB game with 62.5% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Angels players for Wednesday‘s game, looking at profitable historical betting trends:

Best Angels Player Prop Bets Today:

  • Jo Adell has hit the Home Runs Over in 8 of his last 26 games (+29.80 Units / 115% ROI)
  • Taylor Ward has hit the RBIs Over in 15 of his last 25 away games (+14.40 Units / 58% ROI)
  • Kevin Pillar has hit the Runs Over in his last 9 games (+14.35 Units / 159% ROI)
  • Zach Neto has hit the Hits Runs and RBIs Over in 18 of his last 26 games (+11.70 Units / 39% ROI)
  • Zach Neto has hit the Total Bases Over in 23 of his last 31 games (+11.25 Units / 25% ROI)

And here are some favorite MLB player prop bets for Astros players for Wednesday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

  • Kyle Tucker has hit the Home Runs Over in 10 of his last 22 games (+23.65 Units / 108% ROI)
  • Yordan Alvarez has hit the Hits Under in 26 of his last 47 games (+18.25 Units / 31% ROI)
  • Yordan Alvarez has hit the RBIs Under in 22 of his last 25 games at home (+16.85 Units / 42% ROI)
  • Kyle Tucker has hit the Total Bases Over in 29 of his last 47 games (+15.50 Units / 31% ROI)
  • Jeremy Pena has hit the Singles Over in 34 of his last 49 games (+13.25 Units / 19% ROI)
  • The Los Angeles Angels have hit the Team Total Over in 30 of their last 48 games (+9.05 Units / 16% ROI)
  • The Los Angeles Angels have hit the 1st Five Innings (F5) Team Total Under in 29 of their last 49 games (+8.20 Units / 14% ROI)
  • The Los Angeles Angels have hit the 1st Five Innings (F5) Moneyline in 8 of their last 11 games (+7.75 Units / 67% ROI)
  • The Los Angeles Angels have hit the Game Total Over in 16 of their last 26 games (+7.35 Units / 26% ROI)
  • The Los Angeles Angels have covered the Run Line in their last 7 games (+7.00 Units / 72% ROI)
  • The Houston Astros have hit the Team Total Under in 29 of their last 49 games (+7.95 Units / 14% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Team Total Under in 18 of their last 28 games (+7.25 Units / 23% ROI)
  • The Houston Astros have hit the Moneyline in 10 of their last 13 games (+5.30 Units / 25% ROI)
  • The Houston Astros have hit the Game Total Under in 18 of their last 32 games (+4.90 Units / 14% ROI)
  • The Houston Astros have covered the 1st Five Innings (F5) Run Line in 7 of their last 10 games (+3.00 Units / 23% ROI)

Angels Against the Spread (ATS) Record

Against the spread this season, the Angels are 27-22 against the Run Line (-5.7 Units / -7.73% ROI).

  • 19-30 when betting on the Moneyline for -6.75 Units / -13.41% ROI
  • 27-20 when betting on the total runs Over for +4.8 Units / 8.85% ROI
  • 20-27 when betting on the total runs Under for -9.6 Units / -17.93% ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 20-29 against the Run Line (-8.75 Units / -14.96% ROI).

  • 22-27 when betting on the Moneyline for -13.55 Units / -19.41% ROI
  • 20-26 when betting on the total runs Over for -8.25 Units / -15.39% ROI
  • 26-20 when betting on the total runs Under for +4.05 Units / 7.47% ROI

Astros vs Angels Home Run Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 +240 0.5 -300
Kyle Tucker (HOU) 0.5 +340 0.5 -450
Logan O'Hoppe (LAA) 0.5 +375 0.5 -550
Yainer Diaz (HOU) 0.5 +425 0.5 -600
Taylor Ward (LAA) 0.5 +450 0.5 -650

Astros vs Angels Total Hits Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 -275 0.5 +200
Kyle Tucker (HOU) 0.5 -250 0.5 +180
Alex Bregman (HOU) 0.5 -250 0.5 +195
Nolan Schanuel (LAA) 0.5 -210 0.5 +155
Jake Meyers (HOU) 0.5 -190 0.5 +145

Astros vs Angels RBI Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 +110 0.5 -145
Alex Bregman (HOU) 0.5 +125 0.5 -165
Yainer Diaz (HOU) 0.5 +140 0.5 -190
Kyle Tucker (HOU) 0.5 +150 0.5 -200
Logan O'Hoppe (LAA) 0.5 +155 0.5 -210

Astros vs Angels Strikeout Prop Bets Today

Over Under
Cristian Javier (HOU) 5.5 +115 5.5 -150
Griffin Canning (LAA) 4.5 +130 4.5 -175

Tyler Anderson has allowed an OPS of just .056 (18 PA’s) when going through the lineup the second time in a game over the last 14 days — best among AL Starters over the last two weeks; League Avg: .672 — 100th Percentile.

Tyler Anderson has a strikeout rate of just 8% (4 SO in 49 PAs) in PAs ending on elevated fastballs this season — 5th lowest among qualified SPs in MLB; League Avg: 25% — sixth Percentile.

Tyler Anderson has thrown his changeup 31% of the time (264/855) on the first pitch of at-bats since last season — highest in MLB among starting pitchers with at least 82 total CH; League Avg: 10% — 100th Percentile.

Opponents are hitting just .123 (9-for-73) against Tyler Anderson when going through the lineup the second time in a game this season — 2nd best among qualified SPs in MLB; League Avg: .227 — 98th Percentile.

Astros Starting Pitcher Stats & Trends

Opponents are hitting .514 (37-for-72) against Hunter Brown in non-two strike counts this season — highest in MLB among starting pitchers with at least 18 total IP; League Avg: .321 — 0 Percentile.

Hunter Brown has allowed a slugging percentage of .903 (65 Total Bases / 72 ABs) in non-two strike counts this season — highest in MLB among starting pitchers with at least 18 total IP; League Avg: .534 — 0 Percentile.

Hunter Brown has allowed an average Exit Velocity of 91.2 MPH on the 299 breaking pitches put in play against him since the 2022 season — 2nd highest in MLB among starting pitchers with at least 147 total IP; League Avg: 87.5.

Hunter Brown has allowed an OPS of 1.015 (81 PA’s) when going through the lineup the first time in a game this season — 3rd highest in MLB among starting pitchers with at least 18 total IP; League Avg: .681 — second Percentile.

Angels Keys to the Game vs. the Astros

The Angels are just 64-32 (.667) when scoring 5 or more runs since the 2023 season — 2nd lowest in MLB; League Avg: .789.

The Angels are just 16-26 (.381) when tied entering the 7th inning since the 2022 season — 2nd lowest in MLB; League Avg: .500.

The Angels are just 145-14 (.912) when leading entering the 9th inning since the 2022 season — 2nd lowest in MLB; League Avg: .950.

The Angels are just 9-162 (.053) when trailing entering the 8th inning since the 2022 season — tied for 2nd lowest in MLB; League Avg: .095.

Astros Keys to the Game vs. the Angels

The Astros are 17-17 (.500) after a loss as underdogs since the 2022 season — 4th best in MLB; League Avg: .412.

The Astros are 30-23 (.566) after a road win since the 2023 season — 5th best in MLB; League Avg: .485.

The Astros are 104-28 (.788) when they’ve hit 2 or more home runs since the 2022 season — 3rd best in MLB; League Avg: .697.

The Astros are 92-63 (.594) after a loss since the 2022 season — 4th best in MLB; League Avg: .488.

Angels hitters have an OBP of just .278 (1,089 PA’s) against pitchers who have thrown at least 80 pitches in a game since the 2022 season — lowest in MLB; League Avg: .318.

The Angels have a winning percentage of just 27% at home this season — lowest in MLB; League Avg: 52%.

The Angels are batting .240 with two-strikes over the last 14 days — best in MLB; League Avg: .170.

The Angels have answered-back in 41% of innings after an opponent scores in late innings this season — highest in MLB; League Avg: 28%.

Astros hitters have just 742 strikeouts in 4,204 PA’s (18%) against LHP since the 2022 season — best in MLB; League Avg: 22%.

14% of Astros’ hitters plate appearances have lasted only one pitch (1,928/14,187 PA’s) since the 2022 season — highest in MLB; League Avg: 11%.

The Astros have won 91% of road games in which they have scored three or more runs in an inning since the 2022 season — highest in MLB; League Avg: 74%.

The Astros are batting .265 this season — best in MLB; League Avg: .240.

Angels pitchers have walked 198 of 1,873 batters (11%) when facing the leadoff batter in the inning since last season — tied for highest in MLB; League Avg: 8%.

Angels pitchers have an ERA of 5.59 (198.0 IP) at home this season — highest in MLB; League Avg: 3.86.

Angels pitchers have walked 320 of 3,313 batters (10%) when facing the leadoff batter in the inning since the 2022 season — highest in MLB; League Avg: 8%.

Angels pitchers have walked 819 of 8,173 batters (10%) since last season — 4th highest in MLB; League Avg: 9%.

Opponents have a miss rate of 28% against Astros pitchers since the 2022 season — 2nd best in MLB; League Avg: 26%.

Astros pitchers have thrown at least two strikes in their first three pitches to 58% of opposing batters this season — 2nd lowest in MLB; League Avg: 64%.

Opponents have a miss rate of 27% against Astros pitchers since last season — 2nd best in MLB; League Avg: 26%.

Astros pitchers have walked 3 of 126 batters (2%) when facing the leadoff batter in the inning over the last 14 days — best in MLB; League Avg: 7%.

Astros vs. Angels Injuries Tonight That May Affect Prop Bets 

  • Grae Kessinger (Houston Astros): Hamstring, Day-To-Day
  • Justin Verlander (Houston Astros): Shoulder, 15-Day IL
  • Penn Murfee (Houston Astros): Elbow, 15-Day IL
  • Kendall Graveman (Houston Astros): Shoulder, 60-Day IL
  • Jose Abreu (Houston Astros): Hand, Day-To-Day
  • Jose Urquidy (Houston Astros): Forearm, 15-Day IL
  • Oliver Ortega (Houston Astros): Elbow, 15-Day IL
  • Lance McCullers (Houston Astros): Forearm, 60-Day IL
  • Bennett Sousa (Houston Astros): Shoulder, 15-Day IL
  • Forrest Whitley (Houston Astros): Finger, 7-Day IL
  • Shawn Dubin (Houston Astros): Forearm, 15-Day IL
  • Michael Stefanic (Los Angeles Angels): Quadriceps, 10-Day IL
  • Sam Bachman (Los Angeles Angels): Shoulder, 60-Day IL
  • Mickey Moniak (Los Angeles Angels): Illness, Day-To-Day
  • Austin Warren (Los Angeles Angels): Elbow, 60-Day IL
  • Robert Stephenson (Los Angeles Angels): Shoulder, 15-Day IL
  • Aaron Loup (Los Angeles Angels): Shoulder, Out
  • Randal Grichuk (Los Angeles Angels): Ankle, 10-Day IL
  • Kelvin Caceres (Los Angeles Angels): Lat, 60-Day IL
  • Jose Quijada (Los Angeles Angels): Elbow, 60-Day IL

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.