Astros vs Guardians Prediction, Odds & Player Prop Bets Today – MLB, Jun 7

Cleveland Guardians catcher Bo Naylor sits near the bullpen during spring training baseball workouts in Goodyear, Ariz., Friday, Feb. 16, 2024.
(AP Photo/Carolyn Kaster)
  • The Astros are -120 favorites vs the Guardians
  • Astros vs Guardians Over / Under today: 7 Runs
  • Astros / Guardians TV Channel: GDTV | SCHN

The Houston Astros (-118) visit Progressive Field to take on the Cleveland Guardians (-102) on Saturday, June 7, 2025. First pitch is scheduled for 4:10pm EDT in Cleveland, OH, OH.

This season, the Astros are 35-28 against the spread (ATS), while the Guardians are 32-30 ATS.

Astros vs Guardians Starting Pitchers Today:

  • Astros starting pitcher: Hunter Brown 8-3, 1.83 ERA
  • Guardians starting pitcher: Gavin Williams 5-3, 3.84 ERA

Astros vs. Guardians Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Astros-1.5 +150O 7 -102-118
Guardians +1.5 -185U 7 -118-102

Astros vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Saturday‘s MLB game with 56.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


Bet now on Astros vs Guardians and all games with BetMGM


We’ve highlighted some favorite MLB player prop bets for Astros players for Saturday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Bets Today:

  • Isaac Paredes has hit the Home Runs Over in 5 of his last 8 away games (+26.50 Units / 331% ROI)
  • Hunter Brown has hit the Earned Runs Under in 20 of his last 25 games (+16.40 Units / 55% ROI)
  • Jeremy Pena has hit the Hits Over in 17 of his last 25 games (+15.00 Units / 41% ROI)
  • Hunter Brown has hit the Hits Allowed Under in 18 of his last 25 games (+9.85 Units / 30% ROI)
  • Isaac Paredes has hit the Runs Over in 15 of his last 25 games (+9.75 Units / 39% ROI)

And here are some favorite MLB player prop bets for Guardians players for Saturday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Best Bets Today:

  • Jose Ramirez has hit the Singles Over in 18 of his last 25 games at home (+11.75 Units / 44% ROI)
  • Steven Kwan has hit the Runs Under in 16 of his last 20 games at home (+10.80 Units / 37% ROI)
  • Jose Ramirez has hit the Home Runs Over in 4 of his last 9 games at home (+10.65 Units / 118% ROI)
  • Jose Ramirez has hit the Hits Over in 12 of his last 15 games (+10.10 Units / 36% ROI)
  • Jose Ramirez has hit the Hits Runs and RBIs Over in 12 of his last 15 games at home (+8.85 Units / 46% ROI)
  • The Houston Astros have covered the Run Line in 32 of their last 55 games (+11.87 Units / 17% ROI)
  • The Houston Astros have hit the Team Total Under in 38 of their last 63 games (+10.70 Units / 14% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Team Total Under in 18 of their last 26 away games (+10.35 Units / 34% ROI)
  • The Houston Astros have hit the Game Total Under in 20 of their last 30 games (+9.15 Units / 28% ROI)
  • The Houston Astros have hit the Moneyline in 18 of their last 28 games (+7.55 Units / 21% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 17 of their last 25 games (+9.15 Units / 32% ROI)
  • The Cleveland Guardians have hit the Moneyline in 30 of their last 53 games (+8.35 Units / 14% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Under in 13 of their last 18 games at home (+7.90 Units / 36% ROI)
  • The Cleveland Guardians have hit the Team Total Under in 14 of their last 22 games at home (+5.14 Units / 20% ROI)
  • The Cleveland Guardians have covered the Run Line in 10 of their last 16 games (+3.10 Units / 14% ROI)

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 34-29 against the Run Line (+7.22 Units / 9.1% ROI).

  • 35-28 when betting on the Moneyline for +1.55 Units / 1.9% ROI
  • 25-36 when betting on the total runs Over for -14.5 Units / -20.98% ROI
  • 36-25 when betting on the total runs Under for +8.4 Units / 12.07% ROI

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 32-30 against the Run Line (-3 Units / -3.49% ROI).

  • 33-29 when betting on the Moneyline for +5.2 Units / 7.26% ROI
  • 27-32 when betting on the total runs Over for -7.15 Units / -10.66% ROI
  • 32-27 when betting on the total runs Under for +2.25 Units / 3.24% ROI

Guardians vs Astros Home Run Prop Bets Today

Over Under
Christian Walker (HOU) 0.5 +475 0.5 -650
Jose Ramirez (CLE) 0.5 +500 0.5 -700
Kyle Manzardo (CLE) 0.5 +550 0.5 -800
Bo Naylor (CLE) 0.5 +625 0.5 -1000
Isaac Paredes (HOU) 0.5 +650 0.5 -1000

Guardians vs Astros Total Hits Prop Bets Today

Over Under
Yainer Diaz (HOU) 0.5 -250 0.5 +190
Jose Altuve (HOU) 0.5 -225 0.5 +170
Steven Kwan (CLE) 0.5 -220 0.5 +165
Jose Ramirez (CLE) 0.5 -210 0.5 +155
Isaac Paredes (HOU) 0.5 -175 0.5 +135

Guardians vs Astros RBI Prop Bets Today

Over Under
Jose Ramirez (CLE) 0.5 +165 0.5 -220
Christian Walker (HOU) 0.5 +175 0.5 -235
Yainer Diaz (HOU) 0.5 +185 0.5 -250
Isaac Paredes (HOU) 0.5 +195 0.5 -275
Kyle Manzardo (CLE) 0.5 +200 0.5 -275

Guardians vs Astros Strikeout Prop Bets Today

Over Under
Gavin Williams (CLE) 5.5 -150 5.5 +115
Hunter Brown (HOU) 6.5 +120 6.5 -155

Opponents are hitting just .129 (13-for-101) against Hunter Brown when going through the lineup the second time in a game this season — best among qualified SPs in MLB; League Avg: .234 — 100th Percentile.

Hunter Brown has allowed an OBP of just .185 (108 PA’s) when going through the lineup the second time in a game this season — best among qualified SPs in MLB; League Avg: .293 — 100th Percentile.

Hunter Brown has allowed an average Exit Velocity of just 86.7 MPH against his fastballs since the 2023 season (489 balls in play) — 2nd best in MLB among starting pitchers with at least 153 total IP; League Avg: 90.9

51% of Hunter Brown’s strikeouts have come on 97+ MPH fastballs this season — highest among qualified SPs in MLB; League Avg: 8% — 100th Percentile.

Guardians Starting Pitcher Stats & Trends

Gavin Williams has walked 17% of batters in his last two starts — highest in MLB over the last two weeks; League Avg: 7% — first Percentile.

Gavin Williams has walked 17% of batters when going through the lineup the first time in a game over the last 14 days — 2nd highest among AL Starters over the last two weeks; League Avg: 6% — fourth Percentile.

Gavin Williams has a first-pitch strike rate of just 53% (137/258) this season — lowest in MLB among starting pitchers with at least 24 total IP; League Avg: 63% — 0 Percentile.

Opposing hitters have a miss rate of 39% (51/130) against Gavin Williams when he’s behind in the count this season — 2nd best in MLB among starting pitchers with at least 24 total IP; League Avg: 23% — 99th Percentile.

Astros Keys to the Game vs. the Guardians

The Astros were just 0-56 (.000) when trailing entering the 9th inning in the 2024 season — tied for lowest in MLB; League Avg: .050.

The Astros are 67-46 (.593) at home since last season — 5th best in MLB; League Avg: .530.

The Astros are just 1-81 (.012) when trailing entering the 9th inning since last season — 3rd lowest in MLB; League Avg: .048.

The Astros are 20-7 (.741) after a loss this season — 2nd best in MLB; League Avg: .491.

Guardians Keys to the Game vs. the Astros

The Guardians are 97-3 (.970) when leading entering the 7th inning since last season — best in MLB; League Avg: .858.

The Guardians were 71-2 (.973) when leading entering the 7th inning in the 2024 season — best in MLB; League Avg: .856.

The Guardians were 77-2 (.975) when leading entering the 8th inning in the 2024 season — best in MLB; League Avg: .899.

The Guardians are 103-2 (.981) when leading entering the 8th inning since last season — best in MLB; League Avg: .900.

Astros hitters averaged just 3.65 pitches per plate appearance against RHP in the 2024 season — lowest in MLB; League Avg: 3.89.

Astros hitters have put just 29% of balls in play to the right side of the field this season — lowest in MLB; League Avg: 38%.

Astros hitters have put 46% of balls in play to the left side of the field this season — highest in MLB; League Avg: 38%.

Astros hitters have put 43% of balls in play to the left side of the field since the 2023 season — highest in MLB; League Avg: 38%.

Guardians hitters had an OPS of just .662 (1,910 PA’s) against LHP in the 2023 season — lowest in MLB; League Avg: .742.

The Guardians batted just .232 against LHP in the 2023 season — tied for lowest in MLB; League Avg: .254.

Guardians hitters have put just 34% of balls in play to the left side of the field since the 2023 season — lowest in MLB; League Avg: 38%.

Guardians hitters have a swing rate of 64% with two-strikes since the 2023 season — highest in MLB; League Avg: 60%.

Opponents have a miss rate of 29% against Astros pitchers this season — best in MLB; League Avg: 25%.

Opponents have a miss rate of 28% against Astros pitchers since last season — 2nd best in MLB; League Avg: 25%.

Astros pitchers have a strikeout rate of 30% over the last 14 days — best in MLB; League Avg: 22%.

Opponents have a miss rate of 28% against Astros pitchers since the 2023 season — 2nd best in MLB; League Avg: 25%.

Opponents had a groundball batting average of just .207 against Guardians pitchers with runners on base in the 2024 season — best in MLB; League Avg: .262.

Opponents had a groundball batting average of just .223 against Guardians pitchers in the 2024 season — best in MLB; League Avg: .249.

Opponents have a groundball rate of just 39% against Guardians pitchers this season — 3rd lowest in MLB; League Avg: 43%.

Opponents have a groundball batting average of just .234 against Guardians pitchers with runners on base since the 2023 season — 2nd best in MLB; League Avg: .260.

More MLB Reading:


Bet now on Astros vs Guardians and all games with BetMGM


Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.

Split First Bet Offer FBO March Matchups 1080x610
About the Author

BetMGM Betting

Read More @BETMGM

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.