- The Astros are -220 favorites vs the White Sox
- Astros vs White Sox Over / Under today: 8.5 Runs
- Astros / White Sox TV Channel: SCHN | CHSN
The Houston Astros (-200) visit Rate Field to take on the Chicago White Sox (+165) on Sunday, May 4, 2025. First pitch is scheduled for 2:10pm EDT in Chicago, IL.
This season, the Astros are 17-15 against the spread (ATS), while the White Sox are 17-16 ATS.
Astros vs White Sox Starting Pitchers Today:
- Astros starting pitcher: Lance McCullers 0-0, 0.00 ERA
- White Sox starting pitcher: Bryse Wilson 0-1, 5.00 ERA
Astros vs. White Sox Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Astros | -1.5 -125 | O 8.5 -115 | -200 |
| White Sox | +1.5 +105 | U 8.5 -105 | +165 |
Astros vs White Sox Prediction for Today’s Game
Based on recent trends the model predicts the Astros will win Sunday‘s MLB game with 64.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
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We’ve highlighted some favorite MLB player prop bets for Astros players for Sunday‘s game, looking at profitable historical betting trends:
Best Astros Player Prop Bets Today:
- Jeremy Pena has hit the Hits Over in 17 of his last 20 games (+14.55 Units / 37% ROI)
- Jeremy Pena has hit the Singles Over in 19 of his last 25 games (+11.85 Units / 38% ROI)
- Yainer Diaz has hit the Hits Runs and RBIs Under in 18 of his last 25 away games (+11.60 Units / 40% ROI)
- Christian Walker has hit the RBIs Under in 14 of his last 15 away games (+11.15 Units / 33% ROI)
- Yainer Diaz has hit the Home Runs Over in 2 of his last 4 away games (+10.80 Units / 270% ROI)
And here are some favorite MLB player prop bets for White Sox players for Sunday‘s game, looking at profitable historical betting trends:
Best White Sox Player Prop Best Bets Today:
- Luis Robert has hit the Home Runs Over in 3 of his last 7 games (+15.20 Units / 217% ROI)
- Andrew Benintendi has hit the Total Bases Over in 13 of his last 15 games at home (+12.15 Units / 56% ROI)
- Andrew Benintendi has hit the Hits Over in 14 of his last 15 games at home (+11.70 Units / 43% ROI)
- Andrew Benintendi has hit the Singles Over in 11 of his last 15 games at home (+8.40 Units / 54% ROI)
- Miguel Vargas has hit the Hits Runs and RBIs Over in 9 of his last 10 games (+8.25 Units / 57% ROI)
Astros Best Bets Today:
- The Houston Astros have covered the Run Line in 16 of their last 24 games (+10.10 Units / 33% ROI)
- The Houston Astros have hit the Game Total Over in their last 6 games (+6.00 Units / 94% ROI)
- The Houston Astros have hit the 1st Five Innings (F5) Team Total Under in 8 of their last 11 away games (+5.55 Units / 45% ROI)
- The Houston Astros have hit the Team Total Under in 19 of their last 32 games (+5.10 Units / 14% ROI)
- The Houston Astros have hit the Moneyline in 9 of their last 14 games (+1.85 Units / 10% ROI)
White Sox Best Bets Today:
- The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in their last 10 games (+10.70 Units / 96% ROI)
- The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 5 of their last 9 games (+7.65 Units / 84% ROI)
- The Chicago White Sox have hit the Team Total Under in 16 of their last 26 games (+4.90 Units / 16% ROI)
- The Chicago White Sox have hit the Game Total Over in 6 of their last 8 games (+3.70 Units / 41% ROI)
- The Chicago White Sox have covered the Run Line in 6 of their last 9 games (+2.90 Units / 29% ROI)
Astros Against the Spread (ATS) Record
Against the spread this season, the Astros are 18-14 against the Run Line (+5.45 Units / 13.18% ROI).
- 17-15 when betting on the Moneyline for -2.2 Units / -5.3% ROI
- 14-16 when betting on the total runs Over for -3.45 Units / -9.9% ROI
- 16-14 when betting on the total runs Under for +0.35 Units / 0.98% ROI
White Sox Against the Spread (ATS) Record
Against the spread this season, the White Sox are 17-16 against the Run Line (-0.3 Units / -0.78% ROI).
- 9-24 when betting on the Moneyline for -9.05 Units / -27.42% ROI
- 16-15 when betting on the total runs Over for -0.6 Units / -1.65% ROI
- 15-16 when betting on the total runs Under for -2.6 Units / -7.18% ROI
White Sox vs Astros Home Run Prop Bets Today
| Over | Under | |
|---|---|---|
| Christian Walker (HOU) | 0.5 +310 | 0.5 -400 |
| Yainer Diaz (HOU) | 0.5 +475 | 0.5 -650 |
| Jeremy Pena (HOU) | 0.5 +475 | 0.5 -700 |
| Victor Caratini (HOU) | 0.5 +525 | 0.5 -750 |
| Andrew Benintendi (CWS) | 0.5 +525 | 0.5 -750 |
White Sox vs Astros Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Jose Altuve (HOU) | 0.5 -275 | 0.5 +195 |
| Christian Walker (HOU) | 0.5 -220 | 0.5 +170 |
| Isaac Paredes (HOU) | 0.5 -200 | 0.5 +150 |
| Andrew Vaughn (CWS) | 0.5 -200 | 0.5 +150 |
| Jake Meyers (HOU) | 0.5 -190 | 0.5 +140 |
White Sox vs Astros RBI Prop Bets Today
| Over | Under | |
|---|---|---|
| Christian Walker (HOU) | 0.5 +130 | 0.5 -165 |
| Yainer Diaz (HOU) | 0.5 +145 | 0.5 -190 |
| Isaac Paredes (HOU) | 0.5 +160 | 0.5 -210 |
| Jeremy Pena (HOU) | 0.5 +160 | 0.5 -210 |
| Jose Altuve (HOU) | 0.5 +170 | 0.5 -225 |
White Sox vs Astros Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Bryse Wilson (CWS) | 2.5 -135 | 2.5 +100 |
| Lance McCullers Jr. (HOU) | 4.5 +110 | 4.5 -140 |
Astros Starting Pitcher Stats & Trends
Lance McCullers has limited playing time.
White Sox Starting Pitcher Stats & Trends
Bryse Wilson has allowed a slugging percentage of .455 (107 Total Bases / 235 ABs) with two-strikes since last season — highest among qualified RPs in MLB*; League Avg: .244 — 0 Percentile.
Bryse Wilson allowed a slugging percentage of .454 (93 Total Bases / 205 ABs) with two-strikes in the 2024 season — highest among NL Relievers; League Avg: .236 — first Percentile.
Bryse Wilson has allowed an OPS of .746 (259 PA’s) with two-strikes since last season — 2nd highest among qualified RPs in MLB*; League Avg: .477 — second Percentile.
Bryse Wilson allowed an OPS of .739 (224 PA’s) with two-strikes in the 2024 season — 2nd highest among qualified RPs in MLB*; League Avg: .474 — second Percentile.
Astros Keys to the Game vs. the White Sox
The Astros were just 0-56 (.000) when trailing entering the 9th inning in the 2024 season — tied for lowest in MLB; League Avg: .050.
The Astros were just 5-13 (.278) when tied entering the 8th inning in the 2024 season — 3rd lowest in MLB; League Avg: .500.
The Astros are 156-16 (.907) when leading entering the 7th inning since the 2023 season — 4th best in MLB; League Avg: .860.
The Astros are 76-11 (.874) when scoring 5 or more runs since last season — 5th best in MLB; League Avg: .809.
White Sox Keys to the Game vs. the Astros
The White Sox were just 33-23 (.589) when leading entering the 7th inning in the 2024 season — lowest in MLB; League Avg: .856.
The White Sox are just 21-76 (.216) on the road since last season — lowest in MLB; League Avg: .467.
The White Sox are just 40-24 (.625) when leading entering the 7th inning since last season — lowest in MLB; League Avg: .860.
The White Sox are just 5-52 (.088) when their opponents score in the first inning since last season — lowest in MLB; League Avg: .365.
Astros Hitting Stats & Trends
Astros hitters averaged just 3.65 pitches per plate appearance against RHP in the 2024 season — lowest in MLB; League Avg: 3.89.
Astros hitters have put just 29% of balls in play to the right side of the field this season — lowest in MLB; League Avg: 38%.
Astros hitters have put just 33% of balls in play to the right side of the field since the 2023 season — lowest in MLB; League Avg: 37%.
Astros hitters have an OBP of .426 (136 PA’s) when facing the starting pitcher for the 3rd time in a game this season — best in MLB; League Avg: .328.
White Sox Hitting Stats & Trends
White Sox hitters had an OBP of just .278 (5,869 PA’s) in the 2024 season — lowest in MLB; League Avg: .312.
White Sox hitters have an OBP of just .289 (3,200 PA’s) against LHP since the 2023 season — lowest in MLB; League Avg: .318.
White Sox hitters have an OBP of just .288 (6,464 PA’s) at home since the 2023 season — lowest in MLB; League Avg: .320.
White Sox hitters have an OBP of just .213 (6,959 PA’s) with two-strikes since the 2023 season — lowest in MLB; League Avg: .247.
Astros Pitching Stats & Trends
Opponents have a miss rate of 29% against Astros pitchers this season — best in MLB; League Avg: 25%.
Opponents have a miss rate of 28% against Astros pitchers since last season — 2nd best in MLB; League Avg: 25%.
Opponents had a miss rate of 27% against Astros pitchers in the 2024 season — 2nd best in MLB; League Avg: 25%.
Astros pitchers have a strikeout rate of 25% since last season — 2nd best in MLB; League Avg: 22%.
White Sox Pitching Stats & Trends
White Sox pitchers walked 643 of 6,241 batters (10%) in the 2024 season — highest in MLB; League Avg: 8%.
White Sox pitchers have walked 10% of batters since last season — highest in MLB; League Avg: 8%.
White Sox pitchers have walked 10% of batters since the 2023 season — highest in MLB; League Avg: 8%.
Opponents had a groundball batting average of .269 against White Sox pitchers in the 2024 season — highest in MLB; League Avg: .249.
More MLB Reading:
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