Cardinals vs Pirates Prediction, Odds & Player Prop Bets Today – MLB, Apr 8

Pittsburgh Pirates' Andrew McCutchen rounds third after hitting a solo home run off starting pitcher Freddy Peralta (51) during the fourth inning of a baseball game in Pittsburgh, Friday, June 30, 2023.
(AP Photo/Gene J. Puskar)
  • The Pirates are -135 favorites vs the Cardinals
  • Cardinals vs Pirates Over / Under today: 6.5 Runs
  • Cardinals / Pirates TV Channel: FDMW | SNPT

The St. Louis Cardinals (+115) visit PNC Park to take on the Pittsburgh Pirates (-135) on Tuesday, April 8, 2025. First pitch is scheduled for 6:40pm EDT in Pittsburgh, PA.

This season, the Cardinals are 4-6 against the spread (ATS), while the Pirates are 4-7 ATS.

Cardinals vs Pirates Starting Pitchers Today:

  • Cardinals starting pitcher: Sonny Gray 1-0, 5.73 ERA
  • Pirates starting pitcher: Paul Skenes 1-0, 1.46 ERA

Cardinals vs. Pirates Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cardinals+1.5 -210O 6.5 -102+115
Pirates -1.5 +170U 6.5 -118-135

Cardinals vs Pirates Prediction for Today’s Game

Based on recent trends the model predicts the Pirates will win Tuesday‘s MLB game with 55.8% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


Bet now on Cardinals vs Pirates and all games with BetMGM


We’ve highlighted some favorite MLB player prop bets for Cardinals players for Tuesday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today:

  • Brendan Donovan has hit the Home Runs Over in 2 of his last 4 away games (+16.50 Units / 412% ROI)
  • Masyn Winn has hit the Runs Over in 13 of his last 15 away games (+13.65 Units / 82% ROI)
  • Masyn Winn has hit the Hits Runs and RBIs Over in his last 9 away games (+9.30 Units / 91% ROI)
  • Brendan Donovan has hit the RBIs Over in 6 of his last 7 away games (+9.25 Units / 132% ROI)
  • Nolan Arenado has hit the Hits Over in his last 9 games (+9.00 Units / 46% ROI)

And here are some favorite MLB player prop bets for Pirates players for Tuesday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Best Bets Today:

  • Ke’Bryan Hayes has hit the Home Runs Over in 1 of his last 4 games (+9.00 Units / 225% ROI)
  • Oneil Cruz has hit the Hits Runs and RBIs Under in 12 of his last 15 games (+8.45 Units / 42% ROI)
  • Isiah Kiner-Falefa has hit the Total Bases Over in 9 of his last 10 games (+7.25 Units / 43% ROI)
  • Isiah Kiner-Falefa has hit the Hits Over in 9 of his last 10 games (+7.20 Units / 42% ROI)
  • Enmanuel Valdez has hit the Singles Under in 9 of his last 10 games (+6.65 Units / 30% ROI)
  • The St. Louis Cardinals have covered the Run Line in 26 of their last 41 games (+9.15 Units / 16% ROI)
  • The St. Louis Cardinals have hit the Moneyline in 22 of their last 37 games (+8.90 Units / 21% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Over in 12 of their last 15 away games (+8.20 Units / 43% ROI)
  • The St. Louis Cardinals have hit the Game Total Under in 29 of their last 51 games (+6.75 Units / 12% ROI)
  • The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 9 of their last 14 away games (+3.45 Units / 20% ROI)
  • The Pittsburgh Pirates have hit the 1st Five Innings (F5) Team Total Over in 38 of their last 64 games at home (+11.60 Units / 16% ROI)
  • The Pittsburgh Pirates have hit the Game Total Over in 16 of their last 25 games at home (+7.05 Units / 25% ROI)
  • The Pittsburgh Pirates have hit the Team Total Under in 12 of their last 17 games (+5.60 Units / 27% ROI)
  • The Pittsburgh Pirates have covered the Run Line in 67 of their last 123 games (+5.40 Units / 3% ROI)
  • The Pittsburgh Pirates have hit the 1st Five Innings (F5) Moneyline in 9 of their last 14 games at home (+3.65 Units / 17% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 5-5 against the Run Line (-1.3 Units / -8.7% ROI).

  • 4-6 when betting on the Moneyline for -3.2 Units / -26.89% ROI
  • 8-1 when betting on the total runs Over for +6.9 Units / 63.59% ROI
  • 1-8 when betting on the total runs Under for -7.95 Units / -71.3% ROI

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 4-7 against the Run Line (-3.45 Units / -24.91% ROI).

  • 4-7 when betting on the Moneyline for -3.25 Units / -26.42% ROI
  • 6-5 when betting on the total runs Over for +0.35 Units / 2.82% ROI
  • 5-6 when betting on the total runs Under for -1.45 Units / -12.29% ROI

Pirates vs Cardinals Home Run Prop Bets Today

Over Under
Oneil Cruz (PIT) 0.5 +775 0.5 -1200
Andrew McCutchen (PIT) 0.5 +825 0.5 -1400
Bryan Reynolds (PIT) 0.5 +950 0.5 -2000
Enmanuel Valdez (PIT) 0.5 +950 0.5 -2000
Joey Bart (PIT) 0.5 +1000 0.5 -2000

Pirates vs Cardinals Total Hits Prop Bets Today

Over Under
Ke'Bryan Hayes (PIT) 0.5 -210 0.5 +160
Bryan Reynolds (PIT) 0.5 -190 0.5 +145
Brendan Donovan (STL) 0.5 -160 0.5 +120
Nolan Arenado (STL) 0.5 -150 0.5 +115
Isiah Kiner-Falefa (PIT) 0.5 -150 0.5 +115

Pirates vs Cardinals RBI Prop Bets Today

Over Under
Joey Bart (PIT) 0.5 +210 0.5 -295
Andrew McCutchen (PIT) 0.5 +230 0.5 -325
Bryan Reynolds (PIT) 0.5 +230 0.5 -325
Oneil Cruz (PIT) 0.5 +240 0.5 -325
Ke'Bryan Hayes (PIT) 0.5 +250 0.5 -350

Pirates vs Cardinals Strikeout Prop Bets Today

Over Under
Paul Skenes (PIT) 6.5 -145 6.5 +110
Sonny Gray (STL) 6.5 -118 6.5 -110

Opponents have a two strike miss rate of 36% (162/455) against Sonny Gray since last season — best among qualified SPs in MLB; League Avg: 25% — 100th Percentile.

Sonny Gray has a strikeout rate of 58% (218 SO in 377 PAs) with two-strikes since last season — best among qualified SPs in MLB; League Avg: 44% — 100th Percentile.

Opponents had a two strike miss rate of 35% (151/426) against Sonny Gray in the 2024 season — best among qualified SPs in MLB; League Avg: 25% — 100th Percentile.

Sonny Gray allowed an OBP of just .160 (350 PA’s) with two-strikes in the 2024 season — 2nd best among qualified SPs in MLB; League Avg: .232 — 98th Percentile.

Pirates Starting Pitcher Stats & Trends

Paul Skenes has allowed a slugging percentage of just .262 (68 Total Bases / 260 ABs) vs left-handed batters since last season — best in MLB among starting pitchers with at least 68 total IP; League Avg: .410 — 100th Percentile.

Paul Skenes had a strikeout rate of 42% (60/144) versus the bottom of the order in the 2024 season — best in MLB among starting pitchers with at least 64 total IP; League Avg: 24% — 100th Percentile.

Paul Skenes has allowed a slugging percentage of just .262 (68 Total Bases / 260 ABs) vs left-handed batters since the 2023 season — best in MLB among starting pitchers with at least 132 total IP; League Avg: .415 — 100th Percentile.

Paul Skenes has a strike rate of 70% (85/122) vs left-handed batters this season — 2nd highest among qualified SPs in MLB; League Avg: 63% — 98th Percentile.

Cardinals Keys to the Game vs. the Pirates

The Cardinals are just 10-145 (.065) when trailing entering the 8th inning since last season — 4th lowest in MLB; League Avg: .099.

The Cardinals are 29-19 (.604) when tied entering the 7th inning since last season — 3rd best in MLB; League Avg: .499.

The Cardinals are just 31-70 (.307) when their opponents score in the first inning since last season — 5th lowest in MLB; League Avg: .374.

The Cardinals were 18-9 (.667) when tied entering the 7th inning in the 2024 season — tied for 3rd best in MLB; League Avg: .498.

Pirates Keys to the Game vs. the Cardinals

The Pirates were just 65-7 (.903) when leading entering the 9th inning in the 2024 season — 3rd lowest in MLB; League Avg: .949.

The Pirates are just 138-10 (.932) when leading entering the 9th inning since last season — 5th lowest in MLB; League Avg: .950.

The Pirates were just 7-44 (.137) when allowing 10 or more hits in the 2024 season — 2nd lowest in MLB; League Avg: .250.

The Pirates were just 40-47 (.460) after a loss in the 2024 season — 5th lowest in MLB; League Avg: .504.

The Cardinals are batting .223 on pitches out of the zone this season — 2nd best in MLB; League Avg: .144.

The Cardinals are batting .296 on the road this season — best in MLB; League Avg: .223.

The Cardinals have scored 26 runs in late innings this season — 2nd most in MLB.

Cardinals hitters have an OPS of .851 (418 PA’s) this season — 2nd best in MLB; League Avg: .705.

Pirates hitters have 31 strikeouts in 92 PA’s (34%) against LHP this season — 2nd highest in MLB; League Avg: 24%.

Pirates hitters had an OPS of just .701 (1,929 PA’s) against LHP in the 2023 season — 5th lowest in MLB; League Avg: .742.

Pirates hitters are slugging just .509 on the first pitch of at-bats since the 2023 season — 2nd lowest in MLB; League Avg: .578.

Pirates hitters struck out 417 times in 1,598 PA’s (26%) against LHP in the 2024 season — 3rd highest in MLB; League Avg: 23%.

The Cardinals have allowed 11.00 runs per game (44/4) on the road this season — 2nd highest in MLB; League Avg: 4.78.

Opponents had a miss rate of just 23% against Cardinals pitchers in 2023 — 2nd lowest in MLB; League Avg: 26%.

Cardinals pitchers have an ERA of 11.07 (33.1 IP) on the road this season — 2nd highest in MLB; League Avg: 4.61.

Opponents have a miss rate of just 23% against Cardinals pitchers since the 2023 season — 2nd lowest in MLB; League Avg: 26%.

Opponents have a groundball batting average of .292 against Pirates pitchers with the shift since last season — 2nd highest in MLB; League Avg: .248.

Pirates pitchers have allowed 8 home runs this season — tied for 4th fewest in MLB.

Pirates pitchers have 280 three-pitch strikeouts since last season — tied for 3rd most in MLB.

The longest HR allowed by the Pirates pitchers in the 2023 season traveled 459.1 feet — — 5th shortest in MLB; League Avg: 473.2

More MLB Reading:


Bet now on Cardinals vs Pirates and all games with BetMGM


Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.

Split First Bet Offer FBO March Matchups 1080x610
About the Author

BetMGM Betting

Read More @BETMGM

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.