- The Royals are -160 favorites vs the Cardinals
- Cardinals vs Royals Over / Under today: 8.5 Runs
- Cardinals / Royals TV Channel: FDMW | FDKC
The St. Louis Cardinals (+125) visit Kauffman Stadium to take on the Kansas City Royals (-150) on Friday, May 16, 2025. First pitch is scheduled for 7:40pm EDT in Kansas City, MO, MO.
This season, the Cardinals are 24-20 against the spread (ATS), while the Royals are 23-22 ATS.
Cardinals vs Royals Starting Pitchers Today:
- Cardinals starting pitcher: Andre Pallante 3-2, 4.40 ERA
- Royals starting pitcher: Cole Ragans 2-2, 4.24 ERA
Cardinals vs. Royals Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Cardinals | +1.5 -165 | O 8.5 -110 | +125 |
| Royals | -1.5 +140 | U 8.5 -110 | -150 |
Cardinals vs Royals Prediction for Today’s Game
Based on recent trends the model predicts the Royals will win Friday‘s MLB game with 57.8% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
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We’ve highlighted some favorite MLB player prop bets for Cardinals players for Friday‘s game, looking at profitable historical betting trends:
Best Cardinals Player Prop Bets Today:
- Masyn Winn has hit the Home Runs Over in 3 of his last 9 away games (+17.90 Units / 199% ROI)
- Masyn Winn has hit the Hits Over in 19 of his last 25 away games (+12.10 Units / 29% ROI)
- Willson Contreras has hit the Singles Over in 17 of his last 25 games (+10.35 Units / 40% ROI)
- Ivan Herrera has hit the Hits Runs and RBIs Over in 12 of his last 15 away games (+9.00 Units / 56% ROI)
- Ivan Herrera has hit the Total Bases Over in 9 of his last 10 away games (+8.90 Units / 60% ROI)
And here are some favorite MLB player prop bets for Royals players for Friday‘s game, looking at profitable historical betting trends:
Best Royals Player Prop Best Bets Today:
- Kyle Isbel has hit the Home Runs Over in 2 of his last 8 games (+19.00 Units / 238% ROI)
- Salvador Perez has hit the Runs Under in 21 of his last 25 games (+14.60 Units / 34% ROI)
- Jonathan India has hit the Total Bases Over in 14 of his last 20 games (+8.40 Units / 30% ROI)
- Cole Ragans has hit the Walks Allowed Over in 14 of his last 20 games (+7.30 Units / 26% ROI)
- Cavan Biggio has hit the Singles Over in 6 of his last 8 games at home (+6.95 Units / 87% ROI)
Cardinals Best Bets Today:
- The St. Louis Cardinals have covered the Run Line in their last 11 games (+12.75 Units / 84% ROI)
- The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 21 of their last 30 games (+10.45 Units / 29% ROI)
- The St. Louis Cardinals have hit the Moneyline in 15 of their last 21 games (+10.35 Units / 44% ROI)
- The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 16 of their last 34 games (+7.20 Units / 19% ROI)
- The St. Louis Cardinals have hit the Team Total Over in 25 of their last 44 games (+4.32 Units / 9% ROI)
Royals Best Bets Today:
- The Kansas City Royals have hit the Team Total Under in 33 of their last 45 games (+20.75 Units / 40% ROI)
- The Kansas City Royals have hit the Game Total Under in 26 of their last 37 games (+15.05 Units / 37% ROI)
- The Kansas City Royals have hit the Moneyline in 17 of their last 23 games (+12.95 Units / 39% ROI)
- The Kansas City Royals have hit the 1st Five Innings (F5) Moneyline in 14 of their last 21 games (+9.40 Units / 31% ROI)
- The Kansas City Royals have hit the 1st Five Innings (F5) Team Total Under in 15 of their last 22 games at home (+8.40 Units / 34% ROI)
Cardinals Against the Spread (ATS) Record
Against the spread this season, the Cardinals are 26-18 against the Run Line (+3.95 Units / 6.27% ROI).
- 24-20 when betting on the Moneyline for +4.7 Units / 9.61% ROI
- 23-19 when betting on the total runs Over for +2.05 Units / 4.24% ROI
- 19-23 when betting on the total runs Under for -6.5 Units / -13.4% ROI
Royals Against the Spread (ATS) Record
Against the spread this season, the Royals are 23-22 against the Run Line (-6.1 Units / -9.38% ROI).
- 25-20 when betting on the Moneyline for +5.45 Units / 9.45% ROI
- 15-29 when betting on the total runs Over for -16.47 Units / -33.53% ROI
- 29-15 when betting on the total runs Under for +12.55 Units / 25.16% ROI
Royals vs Cardinals Home Run Prop Bets Today
| Over | Under | |
|---|---|---|
| Bobby Witt Jr. (KC) | 0.5 +450 | 0.5 -625 |
| Salvador Perez (KC) | 0.5 +450 | 0.5 -625 |
| Nolan Arenado (STL) | 0.5 +525 | 0.5 -750 |
| Willson Contreras (STL) | 0.5 +575 | 0.5 -800 |
| Masyn Winn (STL) | 0.5 +625 | 0.5 -1000 |
Royals vs Cardinals Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Jonathan India (KC) | 0.5 -250 | 0.5 +185 |
| Vinnie Pasquantino (KC) | 0.5 -250 | 0.5 +185 |
| Freddy Fermin (KC) | 0.5 -225 | 0.5 +175 |
| Brendan Donovan (STL) | 0.5 -225 | 0.5 +170 |
| Lars Nootbaar (STL) | 0.5 -220 | 0.5 +165 |
Royals vs Cardinals RBI Prop Bets Today
| Over | Under | |
|---|---|---|
| Salvador Perez (KC) | 0.5 +105 | 0.5 -140 |
| Bobby Witt Jr. (KC) | 0.5 +120 | 0.5 -155 |
| Vinnie Pasquantino (KC) | 0.5 +125 | 0.5 -160 |
| Michael Massey (KC) | 0.5 +155 | 0.5 -200 |
| Nolan Arenado (STL) | 0.5 +165 | 0.5 -220 |
Royals vs Cardinals Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Andre Pallante (STL) | 2.5 -160 | 2.5 +120 |
| Cole Ragans (KC) | 6.5 -140 | 6.5 +105 |
Cardinals Starting Pitcher Stats & Trends
Opponents had a groundball rate of 77% (173/226) against Andre Pallante in 2023 — highest among NL Relievers; League Avg: 45% — 100th Percentile.
Andre Pallante has a strike rate of just 53% (101/192) in two strike counts this season — lowest among among NL Starters; League Avg: 65% — second Percentile.
Right-handed batters batted .357 (40-for-112) against Andre Pallante in 2023 — highest among NL Relievers; League Avg: .231 — first Percentile.
Andre Pallante allowed an OBP of .444 (133 PA’s) against right-handed batters in 2023 — highest among NL Relievers; League Avg: .304 — first Percentile.
Royals Starting Pitcher Stats & Trends
Cole Ragans has struck out 43% (54/124) of right-handed batters he faced this season — best in MLB among starting pitchers with at least 16 total IP; League Avg: 22% — 100th Percentile.
Right-handed hitters had a miss rate of 34% (433/1,255) against Cole Ragans in the 2024 season — 2nd best among qualified SPs in MLB; League Avg: 26% — 98th Percentile.
Opponents had a miss rate of 32% (488/1,526) against Cole Ragans in the 2024 season — 3rd best among qualified SPs in MLB; League Avg: 26% — 96th Percentile.
Cole Ragans has a strikeout rate of 41% (28 SO in 68 PAs) when going through the lineup the second time in a game this season — best in MLB among starting pitchers with at least 16 total IP; League Avg: 21% — 100th Percentile.
Cardinals Keys to the Game vs. the Royals
The Cardinals are just 0-13 (.000) when trailing entering the 7th inning this season — tied for lowest in MLB; League Avg: .119.
The Cardinals are just 56-59 (.487) vs bottom 10 scoring offenses since the 2023 season They play the Royals (12th best runs scored) today.
The Cardinals were 69-1 (.986) when leading entering the 9th inning in the 2024 season — tied for 2nd best in MLB; League Avg: .949.
The Cardinals are just 10-155 (.061) when trailing entering the 8th inning since the 2023 season — tied for 3rd lowest in MLB; League Avg: .098.
Royals Keys to the Game vs. the Cardinals
The Royals are just 6-60 (.091) when allowing 5 or more runs since last season — 2nd lowest in MLB; League Avg: .192.
The Royals are just 17-86 (.165) when allowing 2 or more home runs since the 2023 season — lowest in MLB; League Avg: .299.
The Royals were just 4-50 (.074) when they allowed 5 or more runs in the 2024 season — 2nd lowest in MLB; League Avg: .196.
The Royals are just 2-8 (.200) vs top 10 scoring offenses this season They play the Cardinals (22nd best runs scored) today.
Cardinals Hitting Stats & Trends
The Cardinals are batting .199 on pitches out of the zone this season — best in MLB; League Avg: .148.
The Cardinals are batting .288 at home this season — 2nd best in MLB; League Avg: .249.
The Cardinals are batting .342 on changeups this season — best in MLB; League Avg: .236.
Cardinals hitters have an OBP of .360 (791 PA’s) at home this season — 2nd best in MLB; League Avg: .323.
Royals Hitting Stats & Trends
Royals hitters have struck out in just 19% of it’s PA’s since last season — 2nd best in MLB; League Avg: 22%.
Royals hitters have an OPS of just .682 (3,401 PA’s) against LHP since the 2023 season — 2nd lowest in MLB; League Avg: .722.
Royals hitters have an OBP of just .287 (6,833 PA’s) on the road since the 2023 season — 3rd lowest in MLB; League Avg: .312.
Royals hitters have an OPS of just .659 (1,875 PA’s) against LHP since last season — 3rd lowest in MLB; League Avg: .706.
Cardinals Pitching Stats & Trends
Cardinals pitchers had a strikeout rate of just 38% with two-strikes in 2023 — tied for 2nd lowest in MLB; League Avg: 43%.
Opponents have a miss rate of just 23% against Cardinals pitchers since the 2023 season — 2nd lowest in MLB; League Avg: 26%.
Cardinals pitchers have a strikeout rate of just 20% since the 2023 season — 2nd lowest in MLB; League Avg: 23%.
Cardinals pitchers walked 95 of 1,431 batters (7%) when facing the leadoff batter in the inning in 2023 — 2nd best in MLB; League Avg: 8%.
Royals Pitching Stats & Trends
Royals pitchers have walked 5% of batters over the last 14 days — best in MLB; League Avg: 8%.
Royals pitchers picked-off 19 runners from first base in 2023 — best in MLB.
The longest HR allowed by the Royals pitchers in the 2024 season traveled 519.4 feet — — longest in MLB; League Avg: 470.4
Royals pitchers had an ERA of 2.97 (460.2 IP) against division opponents in the 2024 season — 2nd best in MLB; League Avg: 4.06.
More MLB Reading:
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