- The Cardinals are +100 favorites vs the Royals
- Cardinals vs Royals Over / Under today: 8.5 Runs
- Cardinals / Royals TV Channel: FDMW | FDKC
The St. Louis Cardinals (+100) visit Kauffman Stadium to take on the Kansas City Royals (-120) on Saturday, May 17, 2025. First pitch is scheduled for 7:10pm EDT in Kansas City, MO.
This season, the Cardinals are 25-20 against the spread (ATS), while the Royals are 23-23 ATS.
Cardinals vs Royals Starting Pitchers Today:
- Cardinals starting pitcher: Miles Mikolas 2-2, 4.32 ERA
- Royals starting pitcher: Seth Lugo 3-4, 3.04 ERA
Cardinals vs. Royals Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Cardinals | -1.5 +165 | O 8.5 -105 | +100 |
| Royals | +1.5 -200 | U 8.5 -115 | -120 |
Cardinals vs Royals Prediction for Today’s Game
Based on recent trends the model predicts the Royals will win Saturday‘s MLB game with 54.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
Bet now on Cardinals vs Royals and all games with BetMGM
We’ve highlighted some favorite MLB player prop bets for Cardinals players for Saturday‘s game, looking at profitable historical betting trends:
Best Cardinals Player Prop Bets Today:
- Alec Burleson has hit the Home Runs Over in 3 of his last 6 games (+22.00 Units / 367% ROI)
- Miles Mikolas has hit the Earned Runs Under in 11 of his last 15 away games (+7.75 Units / 47% ROI)
- Nolan Gorman has hit the Walks Over in 7 of his last 10 games (+7.65 Units / 76% ROI)
- Miles Mikolas has hit the Walks Allowed Under in 12 of his last 15 away games (+6.90 Units / 25% ROI)
- Alec Burleson has hit the Hits Runs and RBIs Over in 6 of his last 7 games (+5.45 Units / 69% ROI)
And here are some favorite MLB player prop bets for Royals players for Saturday‘s game, looking at profitable historical betting trends:
Best Royals Player Prop Best Bets Today:
- Seth Lugo has hit the Strikeouts Under in 10 of his last 15 games at home (+4.65 Units / 25% ROI)
- Seth Lugo has hit the Pitching Outs Over in 5 of his last 6 games (+4.20 Units / 52% ROI)
- Seth Lugo has hit the Earned Runs Under in 4 of his last 5 games at home (+3.20 Units / 47% ROI)
- Seth Lugo has hit the Walks Allowed Under in 3 of his last 4 games (+2.00 Units / 46% ROI)
- Seth Lugo has hit the Hits Allowed Under in 6 of his last 10 games (+1.85 Units / 16% ROI)
Cardinals Best Bets Today:
Royals Best Bets Today:
Cardinals Against the Spread (ATS) Record
Against the spread this season, the Cardinals are 27-18 against the Run Line (+4.95 Units / 7.67% ROI).
- 25-20 when betting on the Moneyline for +6 Units / 12.02% ROI
- 24-19 when betting on the total runs Over for +3.05 Units / 6.17% ROI
- 19-24 when betting on the total runs Under for -7.6 Units / -15.32% ROI
Royals Against the Spread (ATS) Record
Against the spread this season, the Royals are 23-23 against the Run Line (-7.1 Units / -10.76% ROI).
- 25-21 when betting on the Moneyline for +3.95 Units / 6.68% ROI
- 16-29 when betting on the total runs Over for -15.47 Units / -30.8% ROI
- 29-16 when betting on the total runs Under for +11.45 Units / 22.46% ROI
Royals vs Cardinals Home Run Prop Bets Today
| Over | Under | |
|---|---|---|
| Salvador Perez (KC) | 0.5 +450 | 0.5 -625 |
| Vinnie Pasquantino (KC) | 0.5 +450 | 0.5 -625 |
| Bobby Witt Jr. (KC) | 0.5 +450 | 0.5 -650 |
| Jonathan India (KC) | 0.5 +700 | 0.5 -1100 |
| Michael Massey (KC) | 0.5 +725 | 0.5 -1200 |
Royals vs Cardinals Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Vinnie Pasquantino (KC) | 0.5 -275 | 0.5 +200 |
| Jonathan India (KC) | 0.5 -250 | 0.5 +185 |
| Freddy Fermin (KC) | 0.5 -210 | 0.5 +160 |
| Michael Massey (KC) | 0.5 -200 | 0.5 +145 |
| Kyle Isbel (KC) | 0.5 -150 | 0.5 +115 |
Royals vs Cardinals RBI Prop Bets Today
| Over | Under | |
|---|---|---|
| Vinnie Pasquantino (KC) | 0.5 +125 | 0.5 -165 |
| Salvador Perez (KC) | 0.5 +135 | 0.5 -185 |
| Bobby Witt Jr. (KC) | 0.5 +135 | 0.5 -185 |
| Michael Massey (KC) | 0.5 +170 | 0.5 -225 |
| Maikel Garcia (KC) | 0.5 +200 | 0.5 -275 |
Royals vs Cardinals Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Miles Mikolas (STL) | 2.5 -115 | 2.5 -115 |
Cardinals Starting Pitcher Stats & Trends
Opponents batted .225 (89-for-396) against Miles Mikolas with two-strikes in 2023 — highest among qualified SPs in MLB; League Avg: .162 — second Percentile.
Opponents had a miss rate of just 17% (265/1,590) against Miles Mikolas in 2023 — lowest among qualified SPs in MLB; League Avg: 27% — second Percentile.
Right-handed hitters had a miss rate of just 15% (110/720) against Miles Mikolas in the 2024 season — lowest among qualified SPs in MLB; League Avg: 26% — first Percentile.
Opponents are hitting .227 (94-for-415) against Miles Mikolas with two-strikes since last season — 2nd highest among qualified SPs in MLB; League Avg: .161 — fourth Percentile.
Royals Starting Pitcher Stats & Trends
Opponents are hitting just .059 (1-for-17) against Seth Lugo on low fastballs this season — tied for best among qualified SPs in MLB; League Avg: .269 — 100th Percentile.
Seth Lugo has a first-pitch in-zone of 68% (152/225) this season — 2nd best among qualified SPs in MLB; League Avg: 56% — 98th Percentile.
Seth Lugo has a strikeout rate of just 3% (1 SO in 37 PAs) with runners in scoring position this season — lowest among qualified SPs in MLB; League Avg: 22% — first Percentile.
Opponents are hitting just .152 (5-for-33) against Seth Lugo on the first pitch of at-bats this season — 2nd best among qualified SPs in MLB; League Avg: .342 — 98th Percentile.
Cardinals Keys to the Game vs. the Royals
The Cardinals are just 0-16 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .045.
The Cardinals are 87-5 (.946) when leading entering the 8th inning since last season — 3rd best in MLB; League Avg: .902.
The Cardinals are 15-6 (.714) at home this season — tied for 5th best in MLB; League Avg: .567.
The Cardinals are just 0-14 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .085.
Royals Keys to the Game vs. the Cardinals
The Royals are just 6-61 (.090) when allowing 5 or more runs since last season — 2nd lowest in MLB; League Avg: .191.
The Royals were just 4-50 (.074) when they allowed 5 or more runs in the 2024 season — 2nd lowest in MLB; League Avg: .196.
The Royals are just 2-9 (.182) vs top 10 scoring offenses this season They play the Cardinals (22nd best runs scored) today.
The Royals are 58-19 (.753) vs bottom 10 scoring offenses since last season They play the Cardinals (22nd best runs scored) today.
Cardinals Hitting Stats & Trends
The Cardinals are batting .195 on pitches out of the zone this season — best in MLB; League Avg: .148.
Cardinals hitters have an OBP of .340 (1,225 PA’s) against RHP this season — 4th best in MLB; League Avg: .318.
Cardinals hitters slugged just .507 on the first pitch of at-bats in the 2024 season — tied for 4th lowest in MLB; League Avg: .560.
Cardinals hitters have struck out in just 19% of it’s PA’s against RHP this season — 3rd best in MLB; League Avg: 22%.
Royals Hitting Stats & Trends
Royals hitters had an OBP of just .280 (2,958 PA’s) on the road in 2023 — lowest in MLB; League Avg: .316.
Royals hitters have an OPS of just .664 (6,833 PA’s) on the road since the 2023 season — 3rd lowest in MLB; League Avg: .711.
Royals hitters struck out just 298 times in 1,502 PA’s (20%) against LHP in the 2024 season — tied for 3rd best in MLB; League Avg: 23%.
The Royals are batting just .320 on the first pitch of at-bats since the 2023 season — 3rd lowest in MLB; League Avg: .341.
Cardinals Pitching Stats & Trends
Batters facing the Cardinals pitchers have struck out in the zone 46% of the time since last season — 2nd lowest in MLB; League Avg: 50%. since last season — 2nd lowest in MLB; League Avg: 50%.
Opponents have a miss rate of just 22% against Cardinals pitchers this season — tied for lowest in MLB; League Avg: 25%.
Cardinals pitchers have a strikeout rate of just 20% since the 2023 season — 2nd lowest in MLB; League Avg: 23%.
Cardinals pitchers had a strikeout rate of just 38% with two-strikes in 2023 — tied for 2nd lowest in MLB; League Avg: 43%.
Royals Pitching Stats & Trends
Royals pitchers have walked 4% of batters this month (15 games) — best in MLB; League Avg: 8%.
The longest HR allowed by the Royals pitchers in the 2024 season traveled 519.4 feet — — longest in MLB; League Avg: 470.4
Royals pitchers have an ERA of 3.45 (887.2 IP) on the road since last season — best in MLB; League Avg: 4.21.
Royals pitchers have walked 5% of batters over the last 14 days — best in MLB; League Avg: 8%.
More MLB Reading:
Bet now on Cardinals vs Royals and all games with BetMGM
Bet on MLB Odds at BetMGM
Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.
