Cardinals vs Royals Prediction, Odds & Player Prop Bets Today – MLB, May 18

Kansas City Royals' Bobby Witt Jr. during a baseball game against the Colorado Rockies in Kansas City, Mo., Saturday, June 3, 2023.
(AP Photo/Colin E. Braley)
  • The Cardinals are -105 favorites vs the Royals
  • Cardinals vs Royals Over / Under today: 8.5 Runs
  • Cardinals / Royals TV Channel: FDMW | FDKC | KSMO

The St. Louis Cardinals (-105) visit Kauffman Stadium to take on the Kansas City Royals (-115) on Sunday, May 18, 2025. First pitch is scheduled for 2:10pm EDT in Kansas City, MO, MO.

This season, the Cardinals are 26-20 against the spread (ATS), while the Royals are 23-24 ATS.

Cardinals vs Royals Starting Pitchers Today:

  • Cardinals starting pitcher: Matthew Liberatore 3-3, 3.11 ERA
  • Royals starting pitcher: Michael Wacha 3-4, 2.96 ERA

Cardinals vs. Royals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cardinals-1.5 +155O 8 -102-105
Royals +1.5 -190U 8 -118-115

Cardinals vs Royals Prediction for Today’s Game

Based on recent trends the model predicts the Royals will win Sunday‘s MLB game with 52.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Cardinals players for Sunday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today:

  • Alec Burleson has hit the Home Runs Over in 3 of his last 6 games (+22.00 Units / 367% ROI)
  • Lars Nootbaar has hit the Total Bases Over in 17 of his last 25 games (+10.65 Units / 32% ROI)
  • Masyn Winn has hit the Hits Over in 19 of his last 25 away games (+9.75 Units / 22% ROI)
  • Masyn Winn has hit the Hits Runs and RBIs Over in 17 of his last 25 away games (+8.45 Units / 30% ROI)
  • Willson Contreras has hit the Singles Over in 16 of his last 25 games (+8.15 Units / 32% ROI)

And here are some favorite MLB player prop bets for Royals players for Sunday‘s game, looking at profitable historical betting trends:

Best Royals Player Prop Best Bets Today:

  • Salvador Perez has hit the Runs Under in 21 of his last 25 games (+14.60 Units / 35% ROI)
  • Salvador Perez has hit the Hits Under in his last 6 games (+9.15 Units / 102% ROI)
  • Salvador Perez has hit the Hits Runs and RBIs Under in 9 of his last 10 games (+8.60 Units / 80% ROI)
  • Salvador Perez has hit the Total Bases Under in his last 8 games (+8.00 Units / 69% ROI)
  • Bobby Witt Jr. has hit the Singles Under in 12 of his last 20 games (+7.55 Units / 38% ROI)
  • The St. Louis Cardinals have covered the Run Line in their last 13 games (+14.75 Units / 79% ROI)
  • The St. Louis Cardinals have hit the Moneyline in 17 of their last 23 games (+12.65 Units / 49% ROI)
  • The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 23 of their last 32 games (+12.45 Units / 32% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 17 of their last 36 games (+8.60 Units / 22% ROI)
  • The St. Louis Cardinals have hit the Team Total Over in 26 of their last 46 games (+4.27 Units / 8% ROI)
  • The Kansas City Royals have hit the Team Total Under in 35 of their last 47 games (+22.75 Units / 42% ROI)
  • The Kansas City Royals have hit the Game Total Under in 27 of their last 39 games (+14.95 Units / 35% ROI)
  • The Kansas City Royals have hit the 1st Five Innings (F5) Team Total Under in 17 of their last 24 games at home (+10.40 Units / 38% ROI)
  • The Kansas City Royals have hit the Moneyline in 17 of their last 25 games (+10.30 Units / 29% ROI)
  • The Kansas City Royals have hit the 1st Five Innings (F5) Moneyline in 14 of their last 23 games (+7.55 Units / 23% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 28-18 against the Run Line (+5.95 Units / 8.95% ROI).

  • 26-20 when betting on the Moneyline for +7 Units / 13.74% ROI
  • 24-20 when betting on the total runs Over for +1.95 Units / 3.86% ROI
  • 20-24 when betting on the total runs Under for -6.6 Units / -13.01% ROI

Royals Against the Spread (ATS) Record

Against the spread this season, the Royals are 23-24 against the Run Line (-8.1 Units / -12.09% ROI).

  • 25-22 when betting on the Moneyline for +2.8 Units / 4.64% ROI
  • 16-30 when betting on the total runs Over for -16.57 Units / -32.29% ROI
  • 30-16 when betting on the total runs Under for +12.45 Units / 23.91% ROI

Royals vs Cardinals Home Run Prop Bets Today

Over Under
Salvador Perez (KC) 0.5 +425 0.5 -600
Bobby Witt Jr. (KC) 0.5 +450 0.5 -625
Willson Contreras (STL) 0.5 +525 0.5 -750
Hunter Renfroe (KC) 0.5 +525 0.5 -750
Lars Nootbaar (STL) 0.5 +600 0.5 -900

Royals vs Cardinals Total Hits Prop Bets Today

Over Under
Ivan Herrera (STL) 0.5 -275 0.5 +195
Brendan Donovan (STL) 0.5 -275 0.5 +200
Nolan Arenado (STL) 0.5 -250 0.5 +185
Willson Contreras (STL) 0.5 -250 0.5 +185
Maikel Garcia (KC) 0.5 -250 0.5 +185

Royals vs Cardinals RBI Prop Bets Today

Over Under
Salvador Perez (KC) 0.5 +125 0.5 -160
Bobby Witt Jr. (KC) 0.5 +130 0.5 -165
Nolan Arenado (STL) 0.5 +160 0.5 -210
Willson Contreras (STL) 0.5 +170 0.5 -225
Mark Canha (KC) 0.5 +175 0.5 -235

Royals vs Cardinals Strikeout Prop Bets Today

Over Under
Matthew Liberatore (STL) 3.5 -160 3.5 +125
Michael Wacha (KC) 3.5 -110 3.5 -120

Matthew Liberatore has allowed an OPS of just .388 (37 PA’s) when he’s behind in the count this season — best among among NL Starters; League Avg: 1.007 — 100th Percentile.

Opposing hitters have a groundball rate of 69% (24/35) against Matthew Liberatore when he’s behind in the count this season — highest among qualified SPs in MLB; League Avg: 40% — 100th Percentile.

Matthew Liberatore’s K:BB ratio is 15.0 (30/2) against right-handed batters this season — 2nd best among qualified SPs in MLB; League Avg: 3.3 — 98th Percentile.

Matthew Liberatore has walked 4% of batters this season — 4th best among qualified SPs in MLB; League Avg: 8% — 96th Percentile.

Royals Starting Pitcher Stats & Trends

Michael Wacha threw his breaking pitches for a strike just 47% (212/452) of the time in the 2024 season — lowest in MLB among starting pitchers with at least 64 total IP; League Avg: 62% — 0 Percentile.

Hitters swung at 28% of Michael Wacha’s breaking pitches (128/452) in the 2024 season — lowest in MLB among starting pitchers with at least 64 total IP; League Avg: 46% — 0 Percentile.

Michael Wacha allowed a slugging percentage of just .242 (16 Total Bases / 66 ABs) on low fastballs in the 2024 season — 2nd best among qualified SPs in MLB; League Avg: .395 — 97th Percentile.

Michael Wacha has a strikeout rate of just 21% (71 SO in 342 PAs) when going through the lineup the first time in a game since last season — 5th lowest among qualified SPs in MLB; League Avg: 26% — 10th Percentile.

Cardinals Keys to the Game vs. the Royals

The Cardinals are just 0-16 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .044.

The Cardinals are 88-5 (.946) when leading entering the 8th inning since last season — 3rd best in MLB; League Avg: .902.

The Cardinals are 24-1 (.960) when leading entering the 8th inning this season — tied for 4th best in MLB; League Avg: .912.

The Cardinals are 31-22 (.585) when tied entering the 7th inning since the 2023 season — 3rd best in MLB; League Avg: .499.

Royals Keys to the Game vs. the Cardinals

The Royals are just 6-61 (.090) when allowing 5 or more runs since last season — 2nd lowest in MLB; League Avg: .191.

The Royals are just 2-10 (.167) vs top 10 scoring offenses this season They play the Cardinals (22nd best runs scored) today.

The Royals are just 17-86 (.165) when allowing 2 or more home runs since the 2023 season — lowest in MLB; League Avg: .300.

The Royals are just 18-38 (.321) vs top 10 scoring offenses since last season They play the Cardinals (22nd best runs scored) today.

The Cardinals are batting .195 on pitches out of the zone this season — best in MLB; League Avg: .148.

Cardinals hitters struck out just 351 times in 1,755 PA’s (20%) against LHP in the 2024 season — tied for 5th best in MLB; League Avg: 23%.

Cardinals hitters have struck out in just 19% of it’s PA’s against RHP this season — 3rd best in MLB; League Avg: 22%.

Cardinals hitters have an OBP of .360 (791 PA’s) at home this season — 2nd best in MLB; League Avg: .324.

Royals hitters have struck out in just 18% of it’s PA’s against RHP this season — best in MLB; League Avg: 22%.

Royals hitters have struck out in just 19% of it’s PA’s against RHP since last season — 2nd best in MLB; League Avg: 22%.

Royals hitters had an OBP of just .280 (2,958 PA’s) on the road in 2023 — lowest in MLB; League Avg: .316.

The Royals won only 28% of their road games in the 2023 season — 2nd lowest in MLB; League Avg: 48%.

Opponents had a miss rate of just 23% against Cardinals pitchers in 2023 — 2nd lowest in MLB; League Avg: 26%.

Opponents have a miss rate of just 23% against Cardinals pitchers since the 2023 season — 2nd lowest in MLB; League Avg: 26%.

Cardinals pitchers had a strikeout rate of just 19% in 2023 — 2nd lowest in MLB; League Avg: 23%.

Cardinals pitchers have a strikeout rate of just 20% since the 2023 season — 2nd lowest in MLB; League Avg: 23%.

Royals pitchers have walked 4% of batters this month (16 games) — best in MLB; League Avg: 8%.

Royals pitchers have walked 4% of batters over the last 14 days — best in MLB; League Avg: 8%.

Royals pitchers have walked 7% of batters this season — 2nd best in MLB; League Avg: 9%.

The longest HR allowed by the Royals pitchers in the 2024 season traveled 519.4 feet — — longest in MLB; League Avg: 470.4

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.