Cubs vs Diamondbacks Prediction, Odds & Player Prop Bets Today – MLB, Mar 27

Arizona Diamondbacks designated hitter Lourdes Gurriel Jr. bats during the third inning of a baseball game, Saturday, June 10, 2023, in Detroit.
(AP Photo/Carlos Osorio)
  • The Diamondbacks are -140 favorites vs the Cubs
  • Cubs vs Diamondbacks Over / Under today: 8.5 Runs
  • Cubs / Diamondbacks TV Channel: DBTV | MARQ | MLBN

The Chicago Cubs (+110) visit Chase Field to take on the Arizona Diamondbacks (-130) on Thursday, March 27, 2025. First pitch is scheduled for 10:10pm EDT in Phoenix, AZ, USA.

This preseason, the Cubs are 8-7 against the spread (ATS), while the Diamondbacks are 8-11 ATS.

Cubs vs Diamondbacks Starting Pitchers Today:

  • Cubs starting pitcher: Justin Steele 0-1, 11.26 ERA
  • Diamondbacks starting pitcher: Zac Gallen 0-0, 0.00 ERA

Cubs vs. Diamondbacks Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cubs+1.5 -190O 8.5 -120+110
Diamondbacks -1.5 +155U 8.5 +100-130

Cubs vs Diamondbacks Prediction for Today’s Game

Based on recent trends the model predicts the Diamondbacks will win Thursday‘s MLB game with 57.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


Bet now on Cubs vs Diamondbacks and all games with BetMGM


We’ve highlighted some favorite MLB player prop bets for Cubs players for Thursday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Bets Today:

  • Dansby Swanson has hit the Runs Over in 13 of his last 15 away games (+13.70 Units / 80% ROI)
  • Ian Happ has hit the Singles Over in 17 of his last 25 away games (+11.65 Units / 45% ROI)
  • Michael Busch has hit the Home Runs Over in 3 of his last 7 away games (+10.00 Units / 143% ROI)
  • Dansby Swanson has hit the Hits Runs and RBIs Over in 12 of his last 15 away games (+9.25 Units / 54% ROI)
  • Seiya Suzuki has hit the Hits Over in 18 of his last 25 away games (+7.75 Units / 15% ROI)

And here are some favorite MLB player prop bets for Diamondbacks players for Thursday‘s game, looking at profitable historical betting trends:

Best Diamondbacks Player Prop Best Bets Today:

  • Randal Grichuk has hit the Home Runs Over in 4 of his last 7 games (+15.75 Units / 225% ROI)
  • Zac Gallen has hit the Strikeouts Over in 6 of his last 7 games at home (+5.00 Units / 61% ROI)
  • Randal Grichuk has hit the Hits Over in his last 4 games (+4.50 Units / 62% ROI)
  • Randal Grichuk has hit the RBIs Over in his last 3 games (+4.25 Units / 142% ROI)
  • Zac Gallen has hit the Walks Allowed Under in 7 of his last 10 games at home (+4.10 Units / 32% ROI)
  • The Chicago Cubs have hit the Game Total Over in 22 of their last 32 away games (+14.30 Units / 40% ROI)
  • The Chicago Cubs have hit the Moneyline in 44 of their last 75 games (+10.85 Units / 11% ROI)
  • The Chicago Cubs have covered the Run Line in 25 of their last 41 away games (+6.95 Units / 12% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Over in 30 of their last 51 games (+5.60 Units / 9% ROI)
  • The Arizona Diamondbacks have hit the Game Total Over in 69 of their last 106 games (+32.10 Units / 27% ROI)
  • The Arizona Diamondbacks have hit the Moneyline in 64 of their last 105 games (+16.95 Units / 12% ROI)
  • The Arizona Diamondbacks have covered the Run Line in 56 of their last 97 games (+13.40 Units / 11% ROI)
  • The Arizona Diamondbacks have covered the 1st Five Innings (F5) Run Line in 58 of their last 97 games (+12.60 Units / 11% ROI)
  • The Arizona Diamondbacks have hit the 1st Five Innings (F5) Moneyline in 78 of their last 162 games (+9.85 Units / 5% ROI)

Cubs Against the Spread (ATS) Record

Against the spread this preseason, the Cubs were 7-10 against the Run Line (-3.55 Units / -17.36% ROI).

  • 8-7 when betting on the Moneyline for +0.2 Units / 0.88% ROI
  • 8-10 when betting on the total runs Over for -2.95 Units / -14.97% ROI
  • 10-8 when betting on the total runs Under for +1.15 Units / 5.76% ROI

Diamondbacks Against the Spread (ATS) Record

Against the spread this preseason, the Diamondbacks were 8-11 against the Run Line (-3.25 Units / -14.54% ROI).

  • 8-9 when betting on the Moneyline for -3.75 Units / -15.24% ROI
  • 7-12 when betting on the total runs Over for -6.18 Units / -29.53% ROI
  • 12-7 when betting on the total runs Under for +4.3 Units / 20.55% ROI

Diamondbacks vs Cubs Home Run Prop Bets Today

Over Under
Ketel Marte (ARI) 0.5 +350 0.5 -450
Eugenio Suarez (ARI) 0.5 +475 0.5 -650
Kyle Tucker (CHC) 0.5 +500 0.5 -700
Randal Grichuk (ARI) 0.5 +525 0.5 -750
Seiya Suzuki (CHC) 0.5 +575 0.5 -900

Diamondbacks vs Cubs Total Hits Prop Bets Today

Over Under
Nico Hoerner (CHC) 0.5 -250 0.5 +185
Seiya Suzuki (CHC) 0.5 -210 0.5 +160
Kyle Tucker (CHC) 0.5 -210 0.5 +155
Ian Happ (CHC) 0.5 -210 0.5 +155
Dansby Swanson (CHC) 0.5 -210 0.5 +160

Diamondbacks vs Cubs RBI Prop Bets Today

Over Under
Ketel Marte (ARI) 0.5 +145 0.5 -190
Seiya Suzuki (CHC) 0.5 +165 0.5 -220
Michael Busch (CHC) 0.5 +170 0.5 -225
Dansby Swanson (CHC) 0.5 +175 0.5 -235
Nico Hoerner (CHC) 0.5 +185 0.5 -250

Diamondbacks vs Cubs Strikeout Prop Bets Today

Over Under
Zac Gallen (ARI) 4.5 -135 4.5 +100
Justin Steele (CHC) 4.5 +125 4.5 -165

Cubs Keys to the Game vs. the Diamondbacks

The Cubs were 32-10 (.762) when they scored in the first inning in 2024 — 3rd best in MLB; League Avg: .641.

The Cubs are 76-47 (.618) vs bottom 10 scoring offenses since the 2023 season They play the Phillies (fifth best runs scored) today.

Diamondbacks Keys to the Game vs. the Cubs

The Diamondbacks were 20-17 (.541) when their opponents score in the first inning in 2024 — best in MLB; League Avg: .359.

The Diamondbacks are 133-33 (.796) when allowing 4 or fewer runs since the 2023 season — 3rd best in MLB; League Avg: .728.

The Diamondbacks are 9-125 (.067) when trailing entering the 9th inning since the 2023 season — 5th best in MLB; League Avg: .050.

The Diamondbacks are 42-44 (.488) when their opponents score in the first inning since the 2023 season — 2nd best in MLB; League Avg: .374.

The Cubs batted just .227 at home in the 2024 season — 3rd lowest in MLB; League Avg: .244.

Cubs hitters had an OBP of .264 (3,361 PA’s) with two-strikes in 2023 — 4th best in MLB; League Avg: .249.

The Cubs batted .167 on pitches out of the zone in 2023 — 4th best in MLB; League Avg: .151.

Cubs hitters have grounded into 184 double plays in 2,295 opportunities (8%) since the 2023 season — best in MLB; League Avg: 10%.

Diamondbacks hitters had an OBP of .347 (3,080 PA’s) at home in the 2024 season — best in MLB; League Avg: .315.

The Diamondbacks batted .276 at home in the 2024 season — best in MLB; League Avg: .244.

The Diamondbacks batted .277 against division opponents in the 2024 season — best in MLB; League Avg: .243.

Diamondbacks hitters have an OBP of .339 (6,101 PA’s) at home since the 2023 season — best in MLB; League Avg: .320.

Cubs pitchers walked 127 of 1,437 batters (9%) when facing the leadoff batter in the inning in the 2024 season — 3rd highest in MLB; League Avg: 7%.

Cubs pitchers have an ERA of 3.52 (1470.0 IP) at home since the 2023 season — 2nd best in MLB; League Avg: 4.11.

Opponents had a groundball batting average of just .220 against Cubs pitchers in 2023 — 2nd best in MLB; League Avg: .248.

Cubs pitchers had an ERA of 3.08 (733.0 IP) at home in the 2024 season — 2nd best in MLB; League Avg: 3.98.

Opponents have a miss rate of just 24% against Diamondbacks pitchers since the 2022 season — 5th lowest in MLB; League Avg: 26%.

Diamondbacks pitchers allowed opponents to score in three different innings in 53% of their games last season — 2nd highest in MLB; League Avg: 44%.

Opponents had a miss rate of just 24% against Diamondbacks pitchers in the 2024 season — tied for 4th lowest in MLB; League Avg: 25%.

Diamondbacks pitchers had an ERA of 4.68 (739.0 IP) at home in the 2024 season — 3rd highest in MLB; League Avg: 3.98.

More MLB Reading:


Bet now on Cubs vs Diamondbacks and all games with BetMGM


Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.

Split First Bet Offer FBO March Matchups 1080x610
About the Author

BetMGM Betting

Read More @BETMGM

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.