Diamondbacks vs Reds Prediction, Odds & Player Prop Bets Today – MLB, Jun 6

Cincinnati Reds' Spencer Steer runs while flying out during the fourth inning of a baseball game against the Houston Astros, Friday, June 16, 2023, in Houston.
(AP Photo/Eric Christian Smith)
  • The Diamondbacks are -105 favorites vs the Reds
  • Diamondbacks vs Reds Over / Under today: 9.5 Runs
  • Diamondbacks / Reds TV Channel: ATV

The Arizona Diamondbacks (-120) visit Great American Ball Park to take on the Cincinnati Reds (+100) on Friday, June 6, 2025. First pitch is scheduled for 7:10pm EDT in Cincinnati, OH, OH.

This season, the Diamondbacks are 31-31 against the spread (ATS), while the Reds are 33-29 ATS.

Diamondbacks vs Reds Starting Pitchers Today:

  • Diamondbacks starting pitcher: Eduardo Rodriguez 1-3, 7.01 ERA
  • Reds starting pitcher: Nick Lodolo 4-4, 3.13 ERA

Diamondbacks vs. Reds Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Diamondbacks-1.5 +140O 9.5 -110-120
Reds +1.5 -170U 9.5 -110+100

Diamondbacks vs Reds Prediction for Today’s Game

Based on recent trends the model predicts the Diamondbacks will win Friday‘s MLB game with 54.1% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Diamondbacks players for Friday‘s game, looking at profitable historical betting trends:

Best Diamondbacks Player Prop Bets Today:

  • Ketel Marte has hit the Home Runs Over in 5 of his last 10 away games (+16.80 Units / 168% ROI)
  • Lourdes Gurriel Jr. has hit the Hits Over in 14 of his last 15 away games (+13.55 Units / 43% ROI)
  • Gabriel Moreno has hit the Total Bases Over in 11 of his last 15 games (+10.10 Units / 55% ROI)
  • Ketel Marte has hit the Hits Runs and RBIs Over in 12 of his last 15 games (+8.40 Units / 43% ROI)
  • Randal Grichuk has hit the Runs Under in 19 of his last 25 away games (+8.25 Units / 18% ROI)

And here are some favorite MLB player prop bets for Reds players for Friday‘s game, looking at profitable historical betting trends:

Best Reds Player Prop Best Bets Today:

  • Tyler Stephenson has hit the Home Runs Over in 4 of his last 9 games (+17.75 Units / 197% ROI)
  • Spencer Steer has hit the Runs Under in 17 of his last 20 games (+12.50 Units / 36% ROI)
  • Santiago Espinal has hit the Total Bases Under in 16 of his last 20 games (+11.00 Units / 36% ROI)
  • Garrett Hampson has hit the Hits Under in 12 of his last 15 games (+9.55 Units / 58% ROI)
  • Matt McLain has hit the Hits Runs and RBIs Under in 18 of his last 25 games (+9.20 Units / 27% ROI)
  • The Arizona Diamondbacks have covered the 1st Five Innings (F5) Run Line in 30 of their last 46 games (+13.25 Units / 24% ROI)
  • The Arizona Diamondbacks have hit the 1st Five Innings (F5) Moneyline in 26 of their last 46 games (+12.45 Units / 19% ROI)
  • The Arizona Diamondbacks have hit the Game Total Under in 19 of their last 33 games (+5.00 Units / 14% ROI)
  • The Arizona Diamondbacks have hit the Moneyline in 13 of their last 24 away games (+4.15 Units / 16% ROI)
  • The Arizona Diamondbacks have hit the 1st Five Innings (F5) Team Total Over in 13 of their last 21 games (+4.05 Units / 16% ROI)
  • The Cincinnati Reds have hit the Game Total Under in 27 of their last 40 games (+12.60 Units / 28% ROI)
  • The Cincinnati Reds have hit the 1st Five Innings (F5) Team Total Under in 18 of their last 29 games (+6.10 Units / 18% ROI)
  • The Cincinnati Reds have hit the Team Total Under in 6 of their last 7 games (+5.25 Units / 62% ROI)
  • The Cincinnati Reds have hit the 1st Five Innings (F5) Moneyline in 6 of their last 10 games at home (+3.25 Units / 24% ROI)
  • The Cincinnati Reds have covered the Run Line in 6 of their last 10 games at home (+3.05 Units / 23% ROI)

Diamondbacks Against the Spread (ATS) Record

Against the spread this season, the Diamondbacks are 29-33 against the Run Line (-9.21 Units / -11.47% ROI).

  • 31-31 when betting on the Moneyline for -7.9 Units / -9.23% ROI
  • 29-29 when betting on the total runs Over for -3.2 Units / -4.66% ROI
  • 29-29 when betting on the total runs Under for -2.85 Units / -4.21% ROI

Reds Against the Spread (ATS) Record

Against the spread this season, the Reds are 33-29 against the Run Line (-1.6 Units / -1.85% ROI).

  • 30-33 when betting on the Moneyline for -7 Units / -9.12% ROI
  • 25-37 when betting on the total runs Over for -15.2 Units / -22.08% ROI
  • 37-25 when betting on the total runs Under for +9.55 Units / 13.69% ROI

Reds vs Diamondbacks Home Run Prop Bets Today

Over Under
Ketel Marte (ARI) 0.5 +270 0.5 -350
Eugenio Suarez (ARI) 0.5 +310 0.5 -400
Randal Grichuk (ARI) 0.5 +333 0.5 -450
Corbin Carroll (ARI) 0.5 +375 0.5 -500
Tyler Stephenson (CIN) 0.5 +400 0.5 -525

Reds vs Diamondbacks Total Hits Prop Bets Today

Over Under
Gabriel Moreno (ARI) 0.5 -275 0.5 +200
Tyler Stephenson (CIN) 0.5 -250 0.5 +185
Elly De La Cruz (CIN) 0.5 -235 0.5 +175
Randal Grichuk (ARI) 0.5 -225 0.5 +170
Corbin Carroll (ARI) 0.5 -225 0.5 +170

Reds vs Diamondbacks RBI Prop Bets Today

Over Under
Ketel Marte (ARI) 0.5 +125 0.5 -165
Tyler Stephenson (CIN) 0.5 +130 0.5 -165
Eugenio Suarez (ARI) 0.5 +130 0.5 -175
Lourdes Gurriel Jr (ARI) 0.5 +130 0.5 -165
Elly De La Cruz (CIN) 0.5 +150 0.5 -200

Reds vs Diamondbacks Strikeout Prop Bets Today

Over Under
Eduardo Rodriguez (ARI) 3.5 -165 3.5 +130
Nick Lodolo (CIN) 4.5 -110 4.5 -115

Opponents have a line drive rate of 37% (30/81) against Eduardo Rodriguez with runners in scoring position since last season — highest in MLB among starting pitchers with at least 88 total IP; League Avg: 23% — 0 Percentile.

68% of Eduardo Rodriguez’s strikeouts are on pitches in the zone since last season — highest in MLB among starting pitchers with at least 88 total IP; League Avg: 49% — 100th Percentile.

Right-handed hitters have a line drive rate of 31% (71/232) against Eduardo Rodriguez since last season — 2nd highest in MLB among starting pitchers with at least 88 total IP; League Avg: 24% — first Percentile.

Right-handed hitters have a line drive rate of 34% (35/103) against Eduardo Rodriguez this season — 2nd highest in MLB among starting pitchers with at least 24 total IP; League Avg: 24% — first Percentile.

Reds Starting Pitcher Stats & Trends

Opponents are hitting .480 (12-for-25) against Nick Lodolo’s low fastballs this season — highest among qualified SPs in MLB; League Avg: .265 — first Percentile.

Opponents are hitting .323 (140-for-434) against Nick Lodolo at home since the 2023 season — highest in MLB among starting pitchers with at least 153 total IP; League Avg: .242 — 0 Percentile.

Nick Lodolo has a first-pitch strike rate of 70% (203/290) this season — 5th highest among qualified SPs in MLB; League Avg: 63% — 95th Percentile.

Nick Lodolo has allowed a slugging percentage of just .258 (25 Total Bases / 97 ABs) when going through the lineup the second time in a game this season — 3rd best among qualified SPs in MLB; League Avg: .378 — 97th Percentile.

Diamondbacks Keys to the Game vs. the Reds

The Diamondbacks are 158-40 (.794) when allowing 4 or fewer runs since the 2023 season — 3rd best in MLB; League Avg: .723.

The Diamondbacks are 7-85 (.075) when trailing entering the 9th inning since last season — 5th best in MLB; League Avg: .048.

The Diamondbacks are 11-151 (.067) when trailing entering the 9th inning since the 2023 season — 4th best in MLB; League Avg: .049.

The Diamondbacks are 25-7 (.781) when allowing 4 or fewer runs this season — 4th best in MLB; League Avg: .701.

Reds Keys to the Game vs. the Diamondbacks

The Reds are just 0-25 (.000) when trailing entering the 7th inning this season — lowest in MLB; League Avg: .138.

The Reds were just 5-16 (.238) when tied entering the 8th inning in the 2024 season — lowest in MLB; League Avg: .500.

The Reds are just 14-29 (.326) when tied entering the 8th inning since the 2023 season — 2nd lowest in MLB; League Avg: .500.

The Reds are just 0-27 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .097.

Diamondbacks hitters had an OBP of .347 (3,080 PA’s) at home in the 2024 season — best in MLB; League Avg: .315.

Diamondbacks hitters have an OPS of .783 (5,998 PA’s) against RHP since last season — 2nd best in MLB; League Avg: .714.

Diamondbacks hitters had an OBP of .337 (6,284 PA’s) in the 2024 season — best in MLB; League Avg: .312.

Diamondbacks hitters have 168 extra-base hits out of 385 total hits (44%) against RHP this season — best in MLB; League Avg: 34%.

Reds hitters are slugging just .158 on pitches out of the zone since last season — lowest in MLB; League Avg: .203.

Reds hitters are slugging just .171 on pitches out of the zone since the 2023 season — lowest in MLB; League Avg: .206.

The Reds batted just .116 on pitches out of the zone in the 2024 season — lowest in MLB; League Avg: .150.

The Reds are batting just .120 on pitches out of the zone since last season — lowest in MLB; League Avg: .149.

Opponents have a groundball rate of 54% against Diamondbacks pitchers over the last 14 days — highest in MLB; League Avg: 43%.

The Diamondbacks pitchers have allowed their opponents to score first in just 40% of their games since last season — tied for lowest in MLB; League Avg: 50%.

Diamondbacks pitchers had an ERA of 4.68 (739.0 IP) at home in the 2024 season — 3rd highest in MLB; League Avg: 3.98.

The Diamondbacks pitchers have allowed their opponents to score first in just 36% of their games on the road since the 2023 season — 2nd lowest in MLB; League Avg: 44%.

Opponents have a groundball rate of just 39% against Reds pitchers since the 2023 season — lowest in MLB; League Avg: 43%.

Opponents had a groundball rate of just 39% against Reds pitchers in 2023 — 2nd lowest in MLB; League Avg: 43%.

Opponents had a groundball rate of just 39% against Reds pitchers in the 2024 season — lowest in MLB; League Avg: 43%.

Opponents have a groundball rate of just 38% against Reds pitchers this season — 2nd lowest in MLB; League Avg: 43%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.