Giants vs Reds Prediction, Odds & Player Prop Bets Today – MLB, Mar 27

Reds player Tyler Stephenson looking discontented.
(AP Photo/Patrick Semansky)
  • The Giants are -110 favorites vs the Reds
  • Giants vs Reds Over / Under today: 7.5 Runs
  • Giants / Reds TV Channel: FDOH | NSBA

The San Francisco Giants (-110) visit Great American Ball Park to take on the Cincinnati Reds (-110) on Thursday, March 27, 2025. First pitch is scheduled for 4:10pm EDT in Cincinnati, OH, USA.

This preseason, the Giants are 13-4 against the spread (ATS), while the Reds are 8-10 ATS.

Giants vs Reds Starting Pitchers Today:

  • Giants starting pitcher: Logan Webb 0-0, 0.00 ERA
  • Reds starting pitcher: Hunter Greene 0-0, 0.00 ERA

Giants vs. Reds Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Giants-1.5 +155O 7.5 +100-110
Reds +1.5 -190U 7.5 -120-110

Giants vs Reds Prediction for Today’s Game

Based on recent trends the model predicts the Reds will win Thursday‘s MLB game with 51.9% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Giants players for Thursday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Bets Today:

  • LaMonte Wade Jr has hit the Hits Under in 16 of his last 25 away games (+11.20 Units / 40% ROI)
  • Mike Yastrzemski has hit the Home Runs Over in 3 of his last 8 away games (+9.80 Units / 123% ROI)
  • LaMonte Wade Jr has hit the Singles Under in 18 of his last 25 away games (+8.50 Units / 24% ROI)
  • Jung Hoo Lee has hit the Runs Under in 12 of his last 15 games (+8.45 Units / 39% ROI)
  • Logan Webb has hit the Strikeouts Over in 17 of his last 25 games (+7.90 Units / 25% ROI)

And here are some favorite MLB player prop bets for Reds players for Thursday‘s game, looking at profitable historical betting trends:

Best Reds Player Prop Best Bets Today:

  • Jeimer Candelario has hit the Home Runs Over in 3 of his last 7 games at home (+9.00 Units / 129% ROI)
  • Jeimer Candelario has hit the Walks Under in his last 8 games at home (+8.00 Units / 39% ROI)
  • TJ Friedl has hit the Runs Under in 9 of his last 10 games at home (+7.40 Units / 46% ROI)
  • TJ Friedl has hit the Hits Runs and RBIs Under in 14 of his last 20 games (+6.60 Units / 26% ROI)
  • Jeimer Candelario has hit the Singles Under in 14 of his last 20 games at home (+6.60 Units / 23% ROI)
  • The San Francisco Giants have hit the Game Total Over in 47 of their last 81 away games (+15.35 Units / 17% ROI)
  • The San Francisco Giants have hit the 1st Five Innings (F5) Moneyline in 21 of their last 38 away games (+11.47 Units / 26% ROI)
  • The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in 26 of their last 40 away games (+10.55 Units / 22% ROI)
  • The San Francisco Giants have hit the Moneyline in 18 of their last 29 away games (+10.35 Units / 32% ROI)
  • The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Over in 31 of their last 50 away games (+9.33 Units / 16% ROI)
  • The Cincinnati Reds have hit the Team Total Under in 86 of their last 147 games (+17.00 Units / 10% ROI)
  • The Cincinnati Reds have covered the Run Line in 82 of their last 144 games (+11.95 Units / 6% ROI)
  • The Cincinnati Reds have hit the Game Total Under in 77 of their last 146 games (+9.90 Units / 6% ROI)
  • The Cincinnati Reds have hit the 1st Five Innings (F5) Team Total Under in their last 6 games (+6.05 Units / 91% ROI)
  • The Cincinnati Reds have hit the Moneyline in 7 of their last 10 games at home (+5.15 Units / 49% ROI)

Giants Against the Spread (ATS) Record

Against the spread this preseason, the Giants were 12-7 against the Run Line (+4.35 Units / 18.24% ROI).

  • 13-4 when betting on the Moneyline for +9.25 Units / 33.83% ROI
  • 10-9 when betting on the total runs Over for +0.3 Units / 1.44% ROI
  • 9-10 when betting on the total runs Under for -1.87 Units / -8.92% ROI

Reds Against the Spread (ATS) Record

Against the spread this preseason, the Reds were 8-10 against the Run Line (-4.35 Units / -18.25% ROI).

  • 8-9 when betting on the Moneyline for -2.1 Units / -9.23% ROI
  • 6-12 when betting on the total runs Over for -7.2 Units / -35.91% ROI
  • 12-6 when betting on the total runs Under for +5.55 Units / 28.17% ROI

Reds vs Giants Home Run Prop Bets Today

Over Under
Matt Chapman (SF) 0.5 +375 0.5 -525
Willy Adames (SF) 0.5 +400 0.5 -525
Mike Yastrzemski (SF) 0.5 +500 0.5 -700
Elly De La Cruz (CIN) 0.5 +550 0.5 -800
LaMonte Wade Jr (SF) 0.5 +550 0.5 -800

Reds vs Giants Total Hits Prop Bets Today

Over Under
Christian Encarnacion-Strand (CIN) 0.5 -200 0.5 +150
TJ Friedl (CIN) 0.5 -190 0.5 +145
Jung-hoo Lee (SF) 0.5 -190 0.5 +145
Matt McLain (CIN) 0.5 -190 0.5 +145
Willy Adames (SF) 0.5 -185 0.5 +140

Reds vs Giants RBI Prop Bets Today

Over Under
Matt Chapman (SF) 0.5 +150 0.5 -200
Gavin Lux (LAD) 0.5 +170 0.5 -220
Willy Adames (SF) 0.5 +190 0.5 -250
Elly De La Cruz (CIN) 0.5 +190 0.5 -250
Heliot Ramos (SF) 0.5 +200 0.5 -275

Reds vs Giants Strikeout Prop Bets Today

Over Under
Hunter Greene (CIN) 6.5 -105 6.5 -125
Logan Webb (SF) 5.5 +120 5.5 -155

Giants Keys to the Game vs. the Reds

The Giants are just 42-46 (.477) vs bottom 10 scoring offenses since the 2023 season They play the Diamondbacks (first best runs scored) today.

The Giants are 22-138 (.138) when trailing entering the 8th inning since the 2023 season — tied for 5th best in MLB; League Avg: .100.

The Giants were just 20-24 (.455) vs bottom 10 scoring offenses in 2024 They play the Diamondbacks (first best runs scored) today.

The Giants are 132-4 (.971) when leading entering the 9th inning since the 2023 season — 4th best in MLB; League Avg: .949.

Reds Keys to the Game vs. the Giants

The Reds are just 14-27 (.341) when tied entering the 8th inning since the 2023 season — lowest in MLB; League Avg: .500.

The Reds were just 6-16 (.273) when tied entering the 8th inning in 2024 — 2nd lowest in MLB; League Avg: .500.

The Reds were just 3-63 (.045) when trailing entering the 8th inning in 2024 — 2nd lowest in MLB; League Avg: .099.

The Reds were just 9-18 (.333) when tied entering the 7th inning in 2024 — tied for 3rd lowest in MLB; League Avg: .500.

Giants hitters had an OPS of just .683 (1,790 PA’s) against LHP in 2023 — 3rd lowest in MLB; League Avg: .742.

Giants hitters had an OBP of just .232 (3,303 PA’s) with two-strikes in 2023 — 2nd lowest in MLB; League Avg: .249.

Giants hitters had an OPS of just .475 (3,303 PA’s) with two-strikes in 2023 — 2nd lowest in MLB; League Avg: .523.

Giants hitters slugged just .376 against LHP in 2023 — 3rd lowest in MLB; League Avg: .419.

The Reds batted just .116 on pitches out of the zone in the 2024 season — lowest in MLB; League Avg: .150.

Reds hitters slugged just .151 on pitches out of the zone in the 2024 season — lowest in MLB; League Avg: .204.

Reds hitters had an OBP of just .230 (3,144 PA’s) with two-strikes in the 2024 season — 4th lowest in MLB; League Avg: .244.

Reds hitters had 76 extra-base hits out of 177 total hits (43%) when facing the starting pitcher for the 3rd time in a game in the 2024 season — best in MLB; League Avg: 36%.

Opponents had a groundball rate of 50% against Giants pitchers in 2023 — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 49% against Giants pitchers since the 2022 season — highest in MLB; League Avg: 43%.

Giants pitchers walked 403 of 6,039 batters (7%) in 2023 — best in MLB; League Avg: 9%.

Giants pitchers walked 87 of 1,439 batters (6%) when facing the leadoff batter in the inning in 2023 — best in MLB; League Avg: 8%.

Opponents have a groundball rate of just 40% against Reds pitchers since the 2022 season — lowest in MLB; League Avg: 43%.

Opponents had a groundball rate of just 39% against Reds pitchers in 2023 — 2nd lowest in MLB; League Avg: 43%.

Reds pitchers have an ERA of 4.75 (2204.0 IP) at home since the 2022 season — 2nd highest in MLB; League Avg: 4.01.

Reds pitchers walked 140 of 1,443 batters (10%) when facing the leadoff batter in the inning in 2023 — 4th highest in MLB; League Avg: 8%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.