Giants vs Twins Prediction, Odds & Player Prop Bets Today – MLB, May 10

Minnesota Twins' Byron Buxton doubles during the eighth inning of a baseball game against the St. Louis Cardinals Tuesday, Aug. 1, 2023, in St. Louis.
(AP Photo/Jeff Roberson)
  • The Giants are -105 favorites vs the Twins
  • Giants vs Twins Over / Under today: 7 Runs
  • Giants / Twins TV Channel: FOX

The San Francisco Giants (-105) visit Target Field to take on the Minnesota Twins (-115) on Saturday, May 10, 2025. First pitch is scheduled for 7:15pm EDT in Minneapolis, MN.

This season, the Giants are 24-15 against the spread (ATS), while the Twins are 22-17 ATS.

Giants vs Twins Starting Pitchers Today:

  • Giants starting pitcher: Logan Webb 4-2, 2.63 ERA
  • Twins starting pitcher: Joe Ryan 2-2, 2.95 ERA

Giants vs. Twins Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Giants-1.5 +165O 7 -102-105
Twins +1.5 -200U 7 -118-115

Giants vs Twins Prediction for Today’s Game

Based on recent trends the model predicts the Twins will win Saturday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Giants players for Saturday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Bets Today:

  • Heliot Ramos has hit the Runs Over in 13 of his last 20 away games (+10.90 Units / 54% ROI)
  • Matt Chapman has hit the Home Runs Over in 3 of his last 7 games (+7.50 Units / 107% ROI)
  • Christian Koss has hit the Singles Over in 8 of his last 10 games (+7.20 Units / 69% ROI)
  • Logan Webb has hit the Pitching Outs Under in 8 of his last 10 away games (+6.75 Units / 56% ROI)
  • Willy Adames has hit the Total Bases Under in 14 of his last 20 games (+6.75 Units / 24% ROI)

And here are some favorite MLB player prop bets for Twins players for Saturday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Best Bets Today:

  • Trevor Larnach has hit the Home Runs Over in 4 of his last 10 games at home (+17.00 Units / 170% ROI)
  • Trevor Larnach has hit the Hits Runs and RBIs Over in 18 of his last 25 games at home (+11.50 Units / 41% ROI)
  • Brooks Lee has hit the Runs Under in 17 of his last 20 games (+11.20 Units / 28% ROI)
  • Harrison Bader has hit the Total Bases Over in 9 of his last 10 games (+8.25 Units / 58% ROI)
  • Byron Buxton has hit the Hits Over in 12 of his last 15 games (+7.70 Units / 26% ROI)
  • The San Francisco Giants have hit the Game Total Over in 14 of their last 20 away games (+8.50 Units / 39% ROI)
  • The San Francisco Giants have hit the Moneyline in 23 of their last 37 games (+6.10 Units / 12% ROI)
  • The San Francisco Giants have hit the Team Total Under in 13 of their last 20 games (+5.85 Units / 25% ROI)
  • The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Over in 14 of their last 22 away games (+5.05 Units / 20% ROI)
  • The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in 13 of their last 21 away games (+3.75 Units / 15% ROI)
  • The Minnesota Twins have hit the Game Total Under in 21 of their last 30 games (+12.45 Units / 38% ROI)
  • The Minnesota Twins have covered the Run Line in 19 of their last 29 games (+10.90 Units / 30% ROI)
  • The Minnesota Twins have hit the Moneyline in 11 of their last 12 games at home (+8.80 Units / 43% ROI)
  • The Minnesota Twins have covered the 1st Five Innings (F5) Run Line in 20 of their last 32 games (+8.30 Units / 21% ROI)
  • The Minnesota Twins have hit the 1st Five Innings (F5) Moneyline in 13 of their last 18 games at home (+7.90 Units / 29% ROI)

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are 19-20 against the Run Line (-0.35 Units / -0.69% ROI).

  • 24-15 when betting on the Moneyline for +6.05 Units / 11.04% ROI
  • 22-16 when betting on the total runs Over for +4.55 Units / 10.74% ROI
  • 16-22 when betting on the total runs Under for -8.55 Units / -19.68% ROI

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are 22-17 against the Run Line (+6.55 Units / 13.7% ROI).

  • 19-20 when betting on the Moneyline for -4.8 Units / -9.1% ROI
  • 13-23 when betting on the total runs Over for -12.35 Units / -28.62% ROI
  • 23-13 when betting on the total runs Under for +8.8 Units / 20.63% ROI

Twins vs Giants Home Run Prop Bets Today

Over Under
Byron Buxton (MIN) 0.5 +400 0.5 -550
Matt Chapman (SF) 0.5 +400 0.5 -550
Mike Yastrzemski (SF) 0.5 +450 0.5 -625
Willy Adames (SF) 0.5 +475 0.5 -650
LaMonte Wade Jr (SF) 0.5 +600 0.5 -900

Twins vs Giants Total Hits Prop Bets Today

Over Under
Jung-hoo Lee (SF) 0.5 -250 0.5 +180
Byron Buxton (MIN) 0.5 -225 0.5 +170
Ty France (MIN) 0.5 -220 0.5 +165
Carlos Correa (MIN) 0.5 -220 0.5 +165
Trevor Larnach (MIN) 0.5 -190 0.5 +145

Twins vs Giants RBI Prop Bets Today

Over Under
Byron Buxton (MIN) 0.5 +170 0.5 -225
Matt Chapman (SF) 0.5 +185 0.5 -250
Jung-hoo Lee (SF) 0.5 +200 0.5 -275
Brooks Lee (MIN) 0.5 +210 0.5 -285
Ty France (MIN) 0.5 +220 0.5 -300

Twins vs Giants Strikeout Prop Bets Today

Over Under
Joe Ryan (MIN) 6.5 -135 6.5 +105
Logan Webb (SF) 5.5 -135 5.5 +105

Logan Webb has a strikeout rate of 31% vs right-handed batters this season — 10th highest among qualified SPs– 89th Percentile. He had a strikeout rate of just 18% vs right-handed batters last season — eighth lowest among qualified SPs– 13th Percentile.

Logan Webb has a strikeout rate of 59% (22 SO in 37 PAs) in PAs ending on elevated fastballs this season — best among qualified SPs in MLB; League Avg: 23% — 100th Percentile.

Opponents had a groundball rate of 57% (351/617) against Logan Webb in the 2024 season — 4th highest among qualified SPs in MLB; League Avg: 43% — 94th Percentile.

Logan Webb threw his changeup 31% of the time (260/848) on the first pitch of at-bats in 2023 — highest among qualified SPs in MLB; League Avg: 10% — 100th Percentile.

Twins Starting Pitcher Stats & Trends

Joe Ryan has a strikeout rate of 36% (23 SO in 63 PAs) when going through the lineup the first time in a game this season — tied for best among among AL Starters; League Avg: 22% — 100th Percentile.

Joe Ryan has struck out 37% (34/92) of right-handed batters he faced this season — best among qualified SPs in MLB; League Avg: 22% — 100th Percentile.

Right-handed hitters have a groundball rate of just 29% (15/51) against Joe Ryan this season — 2nd lowest among among AL Starters; League Avg: 44% — fourth Percentile.

Right-handed hitters have a miss rate of 36% (69/193) against Joe Ryan this season — tied for 2nd best among qualified SPs in MLB; League Avg: 25% — 98th Percentile.

Giants Keys to the Game vs. the Twins

The Giants are 3-12 (.200) when trailing entering the 8th inning this season — tied for best in MLB; League Avg: .085.

The Giants are 10-4 (.714) after a loss this season — 2nd best in MLB; League Avg: .489.

The Giants are 16-0 (1.000) when scoring 5 or more runs this season — tied for best in MLB; League Avg: .828.

The Giants are 7-4 (.636) vs top 10 scoring offenses this season They play the Twins (11th best runs scored) today.

Twins Keys to the Game vs. the Giants

The Twins are just 1-85 (.012) when trailing entering the 9th inning since last season — 2nd lowest in MLB; League Avg: .049.

The Twins are just 0-11 (.000) when allowing 5 or more runs this season — tied for lowest in MLB; League Avg: .167.

The Twins were just 1-68 (.014) when trailing entering the 9th inning in the 2024 season — 3rd lowest in MLB; League Avg: .050.

The Twins are just 8-12 (.400) after a loss this season — tied for 5th lowest in MLB; League Avg: .489.

Giants hitters had an OPS of just .683 (1,790 PA’s) against LHP in the 2023 season — 3rd lowest in MLB; League Avg: .742.

Giants hitters are slugging just .145 on pitches out of the zone this season — lowest in MLB; League Avg: .201.

The Giants batted just .151 with two-strikes in the 2023 season — 2nd lowest in MLB; League Avg: .172.

Giants hitters slugged just .376 against LHP in the 2023 season — 3rd lowest in MLB; League Avg: .419.

The Twins are batting just .302 on the first pitch of at-bats since last season — 2nd lowest in MLB; League Avg: .334.

Twins hitters are averaging 4.19 pitches per plate appearance against LHP this season — highest in MLB; League Avg: 3.89.

Twins hitters slugged .716 on the first pitch of at-bats in the 2023 season — 2nd best in MLB; League Avg: .596.

Twins hitters slugged just .164 on pitches out of the zone in 2023 — 2nd lowest in MLB; League Avg: .211.

Opponents had a groundball rate of 50% against Giants pitchers in 2023 — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 49% against Giants pitchers since the 2023 season — highest in MLB; League Avg: 43%.

Opponents had a groundball rate of 49% against Giants pitchers in the 2024 season — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 49% against Giants pitchers since last season — highest in MLB; League Avg: 43%.

Twins pitchers have walked 7% of batters this season — best in MLB; League Avg: 9%.

Twins pitchers have walked 7% of batters when facing the leadoff batter in the inning since the 2023 season — tied for 2nd best in MLB; League Avg: 8%.

Twins pitchers have walked 5% of batters over the last 14 days — 2nd best in MLB; League Avg: 9%.

Opponents had a groundball batting average of .293 against Twins pitchers with runners on base in the 2024 season — highest in MLB; League Avg: .262.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.