- The Guardians are +105 favorites vs the Orioles
- Guardians vs Orioles Over / Under today: 8.5 Runs
- Guardians / Orioles TV Channel: MAS2 | GDTV
The Cleveland Guardians (+105) visit Oriole Park at Camden Yards to take on the Baltimore Orioles (-125) on Wednesday, April 16, 2025. First pitch is scheduled for 6:35pm EDT in Baltimore, MD.
This season, the Guardians are 9-7 against the spread (ATS), while the Orioles are 5-11 ATS.
Guardians vs Orioles Starting Pitchers Today:
- Guardians starting pitcher: Gavin Williams 1-0, 3.38 ERA
- Orioles starting pitcher: Dean Kremer 1-2, 8.17 ERA
Guardians vs. Orioles Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Guardians | +1.5 -210 | O 8 -110 | +105 |
| Orioles | -1.5 +170 | U 8 -110 | -125 |
Guardians vs Orioles Prediction for Today’s Game
Based on recent trends the model predicts the Orioles will win Wednesday‘s MLB game with 52.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
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We’ve highlighted some favorite MLB player prop bets for Guardians players for Wednesday‘s game, looking at profitable historical betting trends:
Best Guardians Player Prop Bets Today:
- Steven Kwan has hit the Home Runs Over in 2 of his last 5 games (+24.00 Units / 480% ROI)
- Nolan Jones has hit the Runs Under in 14 of his last 15 games (+12.35 Units / 45% ROI)
- Steven Kwan has hit the Hits Over in 13 of his last 15 away games (+11.40 Units / 37% ROI)
- Steven Kwan has hit the Total Bases Over in 12 of his last 15 away games (+11.25 Units / 55% ROI)
- Steven Kwan has hit the Singles Over in 13 of his last 15 away games (+9.70 Units / 43% ROI)
And here are some favorite MLB player prop bets for Orioles players for Wednesday‘s game, looking at profitable historical betting trends:
Best Orioles Player Prop Best Bets Today:
- Cedric Mullins has hit the Home Runs Over in 2 of his last 4 games at home (+12.10 Units / 303% ROI)
- Gunnar Henderson has hit the Hits Under in 10 of his last 15 games (+9.65 Units / 47% ROI)
- Jordan Westburg has hit the Total Bases Under in his last 9 games (+9.00 Units / 63% ROI)
- Jordan Westburg has hit the RBIs Under in his last 8 games (+8.00 Units / 43% ROI)
- Gunnar Henderson has hit the Hits Runs and RBIs Under in 11 of his last 15 games (+7.55 Units / 47% ROI)
Guardians Best Bets Today:
- The Cleveland Guardians have hit the Game Total Under in 47 of their last 85 away games (+12.00 Units / 13% ROI)
- The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 93 of their last 168 games (+9.46 Units / 5% ROI)
- The Cleveland Guardians have hit the Moneyline in 94 of their last 171 games (+4.95 Units / 2% ROI)
- The Cleveland Guardians have hit the 1st Five Innings (F5) Moneyline in 5 of their last 6 games (+4.20 Units / 48% ROI)
- The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 5 of their last 6 games (+4.10 Units / 59% ROI)
Orioles Best Bets Today:
- The Baltimore Orioles have hit the Game Total Over in 86 of their last 164 games (+15.50 Units / 9% ROI)
- The Baltimore Orioles have hit the Team Total Under in 45 of their last 79 games at home (+6.15 Units / 7% ROI)
- The Baltimore Orioles have covered the Run Line in 83 of their last 164 games (+3.10 Units / 2% ROI)
Guardians Against the Spread (ATS) Record
Against the spread this season, the Guardians are 8-8 against the Run Line (-0.35 Units / -1.62% ROI).
- 9-7 when betting on the Moneyline for +2.15 Units / 10.49% ROI
- 7-8 when betting on the total runs Over for -1.4 Units / -8.14% ROI
- 8-7 when betting on the total runs Under for +0.35 Units / 1.94% ROI
Orioles Against the Spread (ATS) Record
Against the spread this season, the Orioles are 5-11 against the Run Line (-8.75 Units / -37.96% ROI).
- 6-10 when betting on the Moneyline for -5.5 Units / -29.97% ROI
- 9-5 when betting on the total runs Over for +3.7 Units / 21.2% ROI
- 5-9 when betting on the total runs Under for -4.9 Units / -27.61% ROI
Orioles vs Guardians Home Run Prop Bets Today
| Over | Under | |
|---|---|---|
| Gunnar Henderson (BAL) | 0.5 +450 | 0.5 -625 |
| Tyler O’Neill (BAL) | 0.5 +525 | 0.5 -750 |
| Jose Ramirez (CLE) | 0.5 +600 | 0.5 -900 |
| Kyle Manzardo (CLE) | 0.5 +650 | 0.5 -1100 |
| Jhonkensy Noel (CLE) | 0.5 +675 | 0.5 -1100 |
Orioles vs Guardians Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Steven Kwan (CLE) | 0.5 -250 | 0.5 +195 |
| Jordan Westburg (BAL) | 0.5 -235 | 0.5 +180 |
| Gunnar Henderson (BAL) | 0.5 -235 | 0.5 +175 |
| Jose Ramirez (CLE) | 0.5 -225 | 0.5 +170 |
| Ryan Mountcastle (BAL) | 0.5 -200 | 0.5 +150 |
Orioles vs Guardians RBI Prop Bets Today
| Over | Under | |
|---|---|---|
| Jordan Westburg (BAL) | 0.5 +165 | 0.5 -220 |
| Carlos Santana (CLE) | 0.5 +165 | 0.5 -220 |
| Jose Ramirez (CLE) | 0.5 +175 | 0.5 -235 |
| Tyler O’Neill (BAL) | 0.5 +190 | 0.5 -250 |
| Adley Rutschman (BAL) | 0.5 +190 | 0.5 -250 |
Guardians Starting Pitcher Stats & Trends
Gavin Williams has a first-pitch strike rate of just 35% (7/20) over the past seven days (1 games) — lowest among AL Starters over the last week; League Avg: 64% — first Percentile.
22 of Gavin Williams’ 83 breaking pitch strikeouts (27%) have been backdoor since the 2023 season — 5th highest in MLB among starting pitchers with at least 135 total IP; League Avg: 14% — 95th Percentile.
12 of Gavin Williams’ 43 breaking pitch strikeouts (28%) have been backdoor since last season — 6th highest in MLB among starting pitchers with at least 70 total IP; League Avg: 14% — 94th Percentile.
Opposing hitters have a chase rate of 48% (13/27) against Gavin Williams when he’s behind in the count this season — 2nd highest in MLB among starting pitchers with at least 6 total IP; League Avg: 24% — 99th Percentile.
Orioles Starting Pitcher Stats & Trends
Dean Kremer located 57% of his pitches away (1,656/2,925) in 2023 — highest among qualified SPs in MLB; League Avg: 46% — 100th Percentile.
Opponents had a line drive rate of 35% (35/99) versus Dean Kremer with runners in scoring position in 2023 — highest in MLB among starting pitchers with at least 64 total IP; League Avg: 24% — 0 Percentile.
Left-handed hitters had a line drive rate of just 18% (33/185) against Dean Kremer in the 2024 season — 2nd lowest in MLB among starting pitchers with at least 64 total IP; League Avg: 24% — 98th Percentile.
Opponents have a line drive rate of just 13% (13/97) against Dean Kremer with runners in scoring position since last season — 2nd lowest in MLB among starting pitchers with at least 70 total IP; League Avg: 23% — 99th Percentile.
Guardians Keys to the Game vs. the Orioles
The Guardians are just 3-68 (.042) when trailing entering the 8th inning since last season — 2nd lowest in MLB; League Avg: .097.
The Guardians were just 3-61 (.047) when trailing entering the 8th inning in the 2024 season — 2nd lowest in MLB; League Avg: .100.
The Guardians were 77-2 (.975) when leading entering the 8th inning in the 2024 season — best in MLB; League Avg: .899.
The Guardians are just 0-6 (.000) when trailing entering the 7th inning this season — tied for lowest in MLB; League Avg: .117.
Orioles Keys to the Game vs. the Guardians
The Orioles are just 0-9 (.000) when scoring 4 or fewer runs this season — lowest in MLB; League Avg: .280.
The Orioles are 146-22 (.869) when scoring 5 or more runs since the 2023 season — best in MLB; League Avg: .794.
The Orioles are just 2-4 (.333) at home this season — tied for 2nd lowest in MLB; League Avg: .606.
The Orioles are 71-27 (.724) when they’ve scored in the first inning since the 2023 season — 2nd best in MLB; League Avg: .626.
Guardians Hitting Stats & Trends
The Guardians batted just .232 against LHP in the 2023 season — tied for lowest in MLB; League Avg: .254.
Guardians hitters slugged just .367 against LHP in the 2023 season — lowest in MLB; League Avg: .419.
Guardians hitters had an OPS of just .662 (1,910 PA’s) against LHP in the 2023 season — lowest in MLB; League Avg: .742.
Guardians hitters have a swing rate of 64% with two-strikes since the 2023 season — highest in MLB; League Avg: 60%.
Orioles Hitting Stats & Trends
Orioles hitters have put just 33% of balls in play to the left side of the field since last season — lowest in MLB; League Avg: 38%.
Orioles hitters have put just 34% of balls in play to the left side of the field since the 2023 season — 2nd lowest in MLB; League Avg: 38%.
Orioles hitters have an OPS of just .550 (150 PA’s) against LHP this season — 5th lowest in MLB; League Avg: .676.
Orioles hitters are slugging just .208 against LHP this month (9 games) — lowest in MLB; League Avg: .363.
Guardians Pitching Stats & Trends
Opponents had a groundball batting average of just .207 against Guardians pitchers with runners on base in the 2024 season — best in MLB; League Avg: .262.
Opponents have a groundball batting average of just .210 against Guardians pitchers with runners on base since last season — best in MLB; League Avg: .262.
Opponents had a groundball batting average of just .223 against Guardians pitchers in the 2024 season — best in MLB; League Avg: .249.
The Guardians allowed 0.87 runs per game (140/161) in late innings in the 2024 season — best in MLB; League Avg: 1.29.
Orioles Pitching Stats & Trends
Opponents have a miss rate of just 21% against Orioles pitchers this season — lowest in MLB; League Avg: 26%.
Opponents have a miss rate of just 19% against Orioles pitchers this month (11 games) — lowest in MLB; League Avg: 26%.
Orioles pitchers have a strikeout rate of just 16% over the last 14 days — lowest in MLB; League Avg: 22%.
Orioles pitchers have a strikeout rate of just 16% this month (11 games) — lowest in MLB; League Avg: 23%.
More MLB Reading:
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