- The Guardians are -105 favorites vs the Twins
- Guardians vs Twins Over / Under today: 7.5 Runs
- Guardians / Twins TV Channel: GDTV | TWTV | KMSP
The Cleveland Guardians (-105) visit Target Field to take on the Minnesota Twins (-115) on Tuesday, May 20, 2025. First pitch is scheduled for 7:40pm EDT in Minneapolis, MN.
This season, the Guardians are 25-21 against the spread (ATS), while the Twins are 28-19 ATS.
Guardians vs Twins Starting Pitchers Today:
- Guardians starting pitcher: Gavin Williams 3-2, 4.36 ERA
- Twins starting pitcher: Chris Paddack 2-3, 4.08 ERA
Guardians vs. Twins Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Guardians | -1.5 +165 | O 7 -102 | -105 |
| Twins | +1.5 -200 | U 7 -118 | -115 |
Guardians vs Twins Prediction for Today’s Game
Based on recent trends the model predicts the Guardians will win Tuesday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
Bet now on Guardians vs Twins and all games with BetMGM
We’ve highlighted some favorite MLB player prop bets for Guardians players for Tuesday‘s game, looking at profitable historical betting trends:
Best Guardians Player Prop Bets Today:
- Jose Ramirez has hit the Singles Over in 18 of his last 25 games (+11.90 Units / 45% ROI)
- Jose Ramirez has hit the Home Runs Over in 4 of his last 9 games (+9.15 Units / 102% ROI)
- Jose Ramirez has hit the Hits Runs and RBIs Over in 12 of his last 15 games (+9.00 Units / 46% ROI)
- Gabriel Arias has hit the Total Bases Under in 11 of his last 15 games (+8.60 Units / 45% ROI)
- Carlos Santana has hit the RBIs Over in 7 of his last 10 games (+7.75 Units / 77% ROI)
And here are some favorite MLB player prop bets for Twins players for Tuesday‘s game, looking at profitable historical betting trends:
Best Twins Player Prop Best Bets Today:
- Royce Lewis has hit the Hits Under in 9 of his last 10 games at home (+13.05 Units / 130% ROI)
- Trevor Larnach has hit the Home Runs Over in 3 of his last 9 games at home (+12.60 Units / 140% ROI)
- Trevor Larnach has hit the Hits Runs and RBIs Over in 19 of his last 25 games (+12.35 Units / 42% ROI)
- Royce Lewis has hit the Total Bases Under in 9 of his last 10 games at home (+8.95 Units / 65% ROI)
- Brooks Lee has hit the Runs Under in 19 of his last 25 games (+8.25 Units / 17% ROI)
Guardians Best Bets Today:
- The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Under in 15 of their last 20 games (+9.40 Units / 37% ROI)
- The Cleveland Guardians have hit the Moneyline in 22 of their last 37 games (+7.30 Units / 17% ROI)
- The Cleveland Guardians have hit the Game Total Under in 7 of their last 9 games (+5.95 Units / 59% ROI)
- The Cleveland Guardians have hit the Team Total Under in 25 of their last 43 games (+4.79 Units / 9% ROI)
Twins Best Bets Today:
- The Minnesota Twins have covered the Run Line in 25 of their last 37 games (+14.95 Units / 31% ROI)
- The Minnesota Twins have hit the Game Total Under in 26 of their last 38 games (+14.15 Units / 34% ROI)
- The Minnesota Twins have hit the Moneyline in 13 of their last 14 games (+13.00 Units / 77% ROI)
- The Minnesota Twins have covered the 1st Five Innings (F5) Run Line in 25 of their last 40 games (+9.75 Units / 20% ROI)
- The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Over in 10 of their last 12 games (+8.20 Units / 58% ROI)
Guardians Against the Spread (ATS) Record
Against the spread this season, the Guardians are 22-24 against the Run Line (-6.1 Units / -9.59% ROI).
- 25-21 when betting on the Moneyline for +4.15 Units / 7.76% ROI
- 21-22 when betting on the total runs Over for -2.65 Units / -5.28% ROI
- 22-21 when betting on the total runs Under for -0.95 Units / -1.86% ROI
Twins Against the Spread (ATS) Record
Against the spread this season, the Twins are 28-19 against the Run Line (+10.6 Units / 17.88% ROI).
- 26-21 when betting on the Moneyline for +1.55 Units / 2.51% ROI
- 16-28 when betting on the total runs Over for -14.8 Units / -28.52% ROI
- 28-16 when betting on the total runs Under for +10.5 Units / 20.35% ROI
Twins vs Guardians Home Run Prop Bets Today
| Over | Under | |
|---|---|---|
| Kyle Manzardo (CLE) | 0.5 +400 | 0.5 -525 |
| Kody Clemens (MIN) | 0.5 +425 | 0.5 -625 |
| Jose Ramirez (CLE) | 0.5 +425 | 0.5 -600 |
| Bo Naylor (CLE) | 0.5 +450 | 0.5 -625 |
| Trevor Larnach (MIN) | 0.5 +475 | 0.5 -700 |
Twins vs Guardians Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Jose Ramirez (CLE) | 0.5 -250 | 0.5 +190 |
| Trevor Larnach (MIN) | 0.5 -210 | 0.5 +160 |
| Daniel Schneemann (CLE) | 0.5 -210 | 0.5 +155 |
| Brooks Lee (MIN) | 0.5 -200 | 0.5 +150 |
| Kyle Manzardo (CLE) | 0.5 -175 | 0.5 +135 |
Twins vs Guardians RBI Prop Bets Today
| Over | Under | |
|---|---|---|
| Kyle Manzardo (CLE) | 0.5 +155 | 0.5 -200 |
| Jose Ramirez (CLE) | 0.5 +155 | 0.5 -210 |
| Carlos Santana (CLE) | 0.5 +175 | 0.5 -235 |
| Kody Clemens (MIN) | 0.5 +180 | 0.5 -235 |
| Bo Naylor (CLE) | 0.5 +185 | 0.5 -250 |
Twins vs Guardians Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Chris Paddack (MIN) | 3.5 -165 | 3.5 +130 |
| Gavin Williams (CLE) | 5.5 -110 | 5.5 -118 |
Guardians Starting Pitcher Stats & Trends
Gavin Williams has allowed a BABIP of .519 against right-handed batters this season — highest in MLB among starting pitchers with at least 18 total IP; League Avg: .291 — 0 Percentile.
Gavin Williams has allowed an OBP of .457 (92 PA’s) against right-handed batters this season — highest in MLB among starting pitchers with at least 18 total IP; League Avg: .304 — 0 Percentile.
Gavin Williams has allowed an OPS of .994 (92 PA’s) against right-handed batters this season — 3rd highest in MLB among starting pitchers with at least 18 total IP; League Avg: .693 — second Percentile.
Right-handed batters are hitting .375 (30-for-80) against Gavin Williams this season — 2nd highest in MLB among starting pitchers with at least 18 total IP; League Avg: .245 — first Percentile.
Twins Starting Pitcher Stats & Trends
Chris Paddack has a strikeout rate of just 15% (9 SO in 59 PAs) on low non-fastballs this season — 2nd lowest among qualified SPs in MLB; League Avg: 35% — second Percentile.
Chris Paddack has struck out just 13% (12/92) of left-handed batters he faced this season — 2nd lowest among qualified SPs in MLB; League Avg: 22% — third Percentile.
Left-handed hitters have a line drive rate of just 13% (9/71) against Chris Paddack this season — 2nd lowest among qualified SPs in MLB; League Avg: 23% — 98th Percentile.
Chris Paddack has a strike rate of just 59% (154/262) in two strike counts this season — 3rd lowest among qualified SPs in MLB; League Avg: 65% — third Percentile.
Guardians Keys to the Game vs. the Twins
The Guardians are 21-0 (1.000) when leading entering the 8th inning this season — tied for best in MLB; League Avg: .909.
The Guardians are 92-3 (.968) when leading entering the 7th inning since last season — best in MLB; League Avg: .859.
The Guardians are 103-0 (1.000) when leading entering the 9th inning since last season — best in MLB; League Avg: .950.
The Guardians were 82-0 (1.000) when leading entering the 9th inning in the 2024 season — best in MLB; League Avg: .949.
Twins Keys to the Game vs. the Guardians
The Twins are just 1-86 (.011) when trailing entering the 9th inning since last season — 2nd lowest in MLB; League Avg: .049.
The Twins are 164-3 (.982) when leading entering the 9th inning since the 2023 season — tied for 2nd best in MLB; League Avg: .950.
The Twins are just 0-18 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .044.
The Twins are 15-6 (.714) at home this season — 4th best in MLB; League Avg: .562.
Guardians Hitting Stats & Trends
Guardians hitters had an OPS of just .662 (1,910 PA’s) against LHP in the 2023 season — lowest in MLB; League Avg: .742.
Guardians hitters slugged just .367 against LHP in the 2023 season — lowest in MLB; League Avg: .419.
The Guardians batted just .232 against LHP in the 2023 season — tied for lowest in MLB; League Avg: .254.
The Guardians have an average Exit Velocity of 87.7 MPH since the 2023 season — lowest in MLB; League Avg: 89.0.
Twins Hitting Stats & Trends
Twins hitters struck out 1,274 times in 4,710 PA’s (27%) against RHP in 2023 — highest in MLB; League Avg: 23%.
The Twins batted just .150 with two-strikes in the 2023 season — lowest in MLB; League Avg: .172.
Twins hitters slugged just .242 with two-strikes in the 2023 season — tied for lowest in MLB; League Avg: .273.
Twins hitters slugged .716 on the first pitch of at-bats in the 2023 season — 2nd best in MLB; League Avg: .596.
Guardians Pitching Stats & Trends
Opponents had a groundball batting average of just .207 against Guardians pitchers with runners on base in the 2024 season — best in MLB; League Avg: .262.
Opponents had a groundball batting average of just .223 against Guardians pitchers in the 2024 season — best in MLB; League Avg: .249.
Opponents have a groundball batting average of just .221 against Guardians pitchers with runners on base since last season — best in MLB; League Avg: .263.
The Guardians allowed 0.87 runs per game (140/161) in late innings in the 2024 season — best in MLB; League Avg: 1.29.
Twins Pitching Stats & Trends
Twins pitchers have walked 7% of batters this season — best in MLB; League Avg: 9%.
Twins pitchers have walked 7% of batters when facing the leadoff batter in the inning since the 2023 season — 2nd best in MLB; League Avg: 8%.
Twins pitchers have a strikeout rate of 25% since the 2023 season — best in MLB; League Avg: 23%.
Twins pitchers walked 433 of 6,078 batters (7%) in the 2024 season — 3rd best in MLB; League Avg: 8%.
More MLB Reading:
Bet now on Guardians vs Twins and all games with BetMGM
Bet on MLB Odds at BetMGM
Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.
