Orioles vs Mariners Prediction, Odds & Player Prop Bets Today – MLB, Jun 5

Seattle Mariners designated hitter Mitch Haniger, left, follows through on a home run against the Cleveland Guardians during the first inning of a spring training baseball game Sunday, Feb. 25, 2024, in Peoria, Ariz. (AP Photo/Lindsey Wasson)
(AP Photo/Lindsey Wasson)
  • The Mariners are -150 favorites vs the Orioles
  • Orioles vs Mariners Over / Under today: 7.5 Runs
  • Orioles / Mariners TV Channel: MAS2 | RTNW

The Baltimore Orioles (+125) visit T-Mobile Park to take on the Seattle Mariners (-150) on Thursday, June 5, 2025. First pitch is scheduled for 3:40pm EDT in Seattle, WA.

This season, the Orioles are 24-36 against the spread (ATS), while the Mariners are 29-31 ATS.

Orioles vs Mariners Starting Pitchers Today:

  • Orioles starting pitcher: Zach Eflin 4-2, 4.50 ERA
  • Mariners starting pitcher: Bryan Woo 5-2, 2.82 ERA

Orioles vs. Mariners Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Orioles+1.5 -180O 7.5 -115+125
Mariners -1.5 +145U 7.5 -105-150

Orioles vs Mariners Prediction for Today’s Game

Based on recent trends the model predicts the Mariners will win Thursday‘s MLB game with 60.5% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Orioles players for Thursday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Bets Today:

  • Dylan Carlson has hit the Home Runs Over in 2 of his last 9 games (+14.00 Units / 156% ROI)
  • Dylan Carlson has hit the Runs Under in 17 of his last 20 games (+10.50 Units / 24% ROI)
  • Gunnar Henderson has hit the RBIs Under in 13 of his last 15 games (+9.10 Units / 33% ROI)
  • Jackson Holliday has hit the Total Bases Under in 17 of his last 25 away games (+8.95 Units / 27% ROI)
  • Gunnar Henderson has hit the Hits Runs and RBIs Under in 17 of his last 25 away games (+8.45 Units / 28% ROI)

And here are some favorite MLB player prop bets for Mariners players for Thursday‘s game, looking at profitable historical betting trends:

Best Mariners Player Prop Best Bets Today:

  • Julio Rodriguez has hit the Hits Over in 17 of his last 25 games (+11.45 Units / 26% ROI)
  • Jorge Polanco has hit the Total Bases Under in his last 10 games (+10.70 Units / 72% ROI)
  • Rowdy Tellez has hit the Singles Under in 17 of his last 20 games at home (+10.70 Units / 26% ROI)
  • Julio Rodriguez has hit the Hits Runs and RBIs Over in 17 of his last 25 games (+7.50 Units / 23% ROI)
  • Bryan Woo has hit the Pitching Outs Over in 8 of his last 10 games (+7.45 Units / 58% ROI)
  • The Baltimore Orioles have hit the Team Total Under in 35 of their last 55 games (+12.35 Units / 19% ROI)
  • The Baltimore Orioles have hit the Game Total Under in 18 of their last 25 away games (+11.18 Units / 40% ROI)
  • The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Under in 16 of their last 23 away games (+8.49 Units / 29% ROI)
  • The Baltimore Orioles have hit the Moneyline in 8 of their last 10 games (+6.35 Units / 51% ROI)
  • The Baltimore Orioles have hit the 1st Five Innings (F5) Moneyline in 8 of their last 12 games (+6.00 Units / 42% ROI)
  • The Seattle Mariners have hit the Game Total Over in 17 of their last 23 games at home (+10.60 Units / 43% ROI)
  • The Seattle Mariners have hit the Team Total Under in 10 of their last 14 games at home (+5.40 Units / 33% ROI)
  • The Seattle Mariners have hit the 1st Five Innings (F5) Team Total Under in 18 of their last 29 games (+4.95 Units / 14% ROI)
  • The Seattle Mariners have covered the Run Line in 25 of their last 48 games (+3.10 Units / 5% ROI)
  • The Seattle Mariners have hit the Moneyline in 28 of their last 48 games (+2.75 Units / 4% ROI)

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are 20-39 against the Run Line (-23.06 Units / -29.93% ROI).

  • 24-36 when betting on the Moneyline for -19.25 Units / -26.16% ROI
  • 27-30 when betting on the total runs Over for -5.73 Units / -8.73% ROI
  • 30-27 when betting on the total runs Under for +0.13 Units / 0.2% ROI

Mariners Against the Spread (ATS) Record

Against the spread this season, the Mariners are 29-31 against the Run Line (-1.6 Units / -2.15% ROI).

  • 32-28 when betting on the Moneyline for -3.6 Units / -4.46% ROI
  • 32-26 when betting on the total runs Over for +3.3 Units / 5.02% ROI
  • 26-32 when betting on the total runs Under for -9.57 Units / -14.41% ROI

Mariners vs Orioles Home Run Prop Bets Today

Over Under
Cal Raleigh (SEA) 0.5 +280 0.5 -350
Gunnar Henderson (BAL) 0.5 +350 0.5 -450
Colton Cowser (BAL) 0.5 +425 0.5 -600
Jorge Polanco (SEA) 0.5 +500 0.5 -700
Randy Arozarena (SEA) 0.5 +525 0.5 -750

Mariners vs Orioles Total Hits Prop Bets Today

Over Under
Gunnar Henderson (BAL) 0.5 -275 0.5 +200
Jackson Holliday (BAL) 0.5 -235 0.5 +175
J.P. Crawford (SEA) 0.5 -210 0.5 +155
Jorge Polanco (SEA) 0.5 -210 0.5 +160
Adley Rutschman (BAL) 0.5 -200 0.5 +150

Mariners vs Orioles RBI Prop Bets Today

Over Under
Cal Raleigh (SEA) 0.5 +130 0.5 -175
Gunnar Henderson (BAL) 0.5 +155 0.5 -210
Julio Rodriguez (SEA) 0.5 +190 0.5 -250
Colton Cowser (BAL) 0.5 +195 0.5 -250
Randy Arozarena (SEA) 0.5 +210 0.5 -275

Mariners vs Orioles Strikeout Prop Bets Today

Over Under
Bryan Woo (SEA) 5.5 -125 5.5 -105
Zach Eflin (BAL) 4.5 -115 4.5 -115

Zach Eflin walked 4% of batters in the 2024 season — tied for 2nd best among qualified SPs in MLB; League Avg: 7% — 98th Percentile.

Zach Eflin had a strike rate of 70% (857/1,226) against right-handed batters in the 2024 season — highest among qualified SPs in MLB; League Avg: 66% — 100th Percentile.

Zach Eflin has walked 2% of right-handed batters in the 2024 season — 2nd best among qualified SPs in MLB; League Avg: 6% — 98th Percentile.

Zach Eflin allowed a slugging percentage of just .133 (11 Total Bases / 83 ABs) on elevated fastballs in 2023 — 2nd best in MLB among starting pitchers with at least 64 total IP; League Avg: .404 — 99th Percentile.

Mariners Starting Pitcher Stats & Trends

Bryan Woo has walked 1% of batters when going through the lineup the second time in a game this season — best among qualified SPs in MLB; League Avg: 7% — 100th Percentile.

Bryan Woo has thrown fastballs 72% of the time (384/534) against right-handed batters this season — highest among qualified SPs in MLB; League Avg: 49% — 100th Percentile.

Bryan Woo has thrown 60% of his pitches in the strike zone (276/460) vs left-handed batters this season — best among qualified SPs in MLB; League Avg: 52% — 100th Percentile.

Bryan Woo has a strike rate of 72% (944/1,309) against right-handed batters since last season — highest in MLB among starting pitchers with at least 88 total IP; League Avg: 65% — 100th Percentile.

Orioles Keys to the Game vs. the Mariners

The Orioles are just 7-30 (.189) when scoring 4 or fewer runs this season — 3rd lowest in MLB; League Avg: .298.

The Orioles were 36-10 (.783) when they scored in the first inning in the 2024 season — 2nd best in MLB; League Avg: .641.

The Orioles were 45-9 (.833) when they had 10 or more hits in the 2024 season — 3rd best in MLB; League Avg: .750.

The Orioles are just 5-16 (.238) when their opponents score in the first inning this season — 5th lowest in MLB; League Avg: .373.

Mariners Keys to the Game vs. the Orioles

The Mariners are 175-3 (.983) when leading entering the 9th inning since the 2023 season — tied for best in MLB; League Avg: .950.

The Mariners were 58-5 (.921) when they scored 5 or more runs in the 2024 season — best in MLB; League Avg: .804.

The Mariners are 3-22 (.120) when trailing entering the 9th inning this season — best in MLB; League Avg: .041.

The Mariners are 79-9 (.898) when scoring 5 or more runs since last season — best in MLB; League Avg: .807.

Orioles hitters are slugging just .270 against LHP this season — lowest in MLB; League Avg: .375.

Orioles hitters have an OPS of just .545 (542 PA’s) against LHP this season — lowest in MLB; League Avg: .683.

Orioles hitters are slugging just .155 on breaking pitches against LHP this season — lowest in MLB; League Avg: .337.

The Orioles are batting just .198 against LHP this season — lowest in MLB; League Avg: .237.

The Mariners are batting just .208 when facing the starting pitcher for the 3rd time in a game since last season — lowest in MLB; League Avg: .261.

The Mariners are batting just .214 at home since last season — lowest in MLB; League Avg: .246.

The Mariners batted just .207 when facing the starting pitcher for the 3rd time in a game in the 2024 season — lowest in MLB; League Avg: .263.

The Mariners are batting just .225 when facing the starting pitcher for the 3rd time in a game since the 2023 season — lowest in MLB; League Avg: .263.

Orioles pitchers have walked 12% of batters when facing the leadoff batter in the inning this season — highest in MLB; League Avg: 8%.

Opponents have a miss rate of just 23% against Orioles pitchers this season — 4th lowest in MLB; League Avg: 25%.

In games when their opponents scored three or more runs in an inning, the Orioles have not won a game this season — lowest in MLB; League Avg: 24%.

Orioles pitchers allowed an OBP of just .281 (1,446 PA’s) when facing the leadoff batter in the inning in the 2024 season — 2nd best in MLB; League Avg: .305.

Mariners pitchers allowed an OBP of just .251 (1,441 PA’s) when facing the leadoff batter in the inning in the 2024 season — best in MLB; League Avg: .305.

Mariners pitchers walked 369 of 5,801 batters (6%) in the 2024 season — best in MLB; League Avg: 8%.

Mariners pitchers have walked 6% of batters when facing the leadoff batter in the inning since last season — best in MLB; League Avg: 8%.

Mariners pitchers walked 76 of 1,441 batters (5%) when facing the leadoff batter in the inning in the 2024 season — best in MLB; League Avg: 7%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.