Phillies vs Cubs Prediction, Odds & Player Prop Bets Today – MLB, Apr 25

Chicago Cubs' Nico Hoerner watches his RBI sacrifice fly during the fifth inning of a baseball game against the Colorado Rockies Saturday, Sept. 23, 2023, in Chicago. Chicago won 6-3. (AP Photo/Paul Beaty)
(AP Photo/Paul Beaty)
  • The Cubs are -145 favorites vs the Phillies
  • Phillies vs Cubs Over / Under today: 8 Runs
  • Phillies / Cubs TV Channel: MARQ | NSPA | MLBN

The Philadelphia Phillies (+120) visit Wrigley Field to take on the Chicago Cubs (-145) on Friday, April 25, 2025. First pitch is scheduled for 2:20pm EDT in Chicago, IL, IL.

This season, the Phillies are 13-12 against the spread (ATS), while the Cubs are 14-12 ATS.

Phillies vs Cubs Starting Pitchers Today:

  • Phillies starting pitcher: Taijuan Walker 1-1, 2.25 ERA
  • Cubs starting pitcher: Colin Rea 0-0, 1.32 ERA

Phillies vs. Cubs Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Phillies+1.5 -190O 8 +100+120
Cubs -1.5 +155U 8 -120-145

Phillies vs Cubs Prediction for Today’s Game

Based on recent trends the model predicts the Cubs will win Friday‘s MLB game with 53.9% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Phillies players for Friday‘s game, looking at profitable historical betting trends:

Best Phillies Player Prop Bets Today:

  • Bryson Stott has hit the Hits Over in 17 of his last 20 games (+11.75 Units / 32% ROI)
  • Kyle Schwarber has hit the Singles Over in 14 of his last 25 away games (+11.50 Units / 46% ROI)
  • Max Kepler has hit the RBIs Under in 17 of his last 20 games (+11.05 Units / 23% ROI)
  • Bryson Stott has hit the Home Runs Over in 2 of his last 9 away games (+10.90 Units / 121% ROI)
  • Alec Bohm has hit the Total Bases Over in 9 of his last 10 games (+9.65 Units / 65% ROI)

And here are some favorite MLB player prop bets for Cubs players for Friday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Best Bets Today:

  • Pete Crow-Armstrong has hit the Home Runs Over in 4 of his last 9 games (+25.50 Units / 283% ROI)
  • Pete Crow-Armstrong has hit the Runs Over in 14 of his last 20 games (+17.30 Units / 87% ROI)
  • Ian Happ has hit the Singles Over in 16 of his last 25 games at home (+10.00 Units / 39% ROI)
  • Pete Crow-Armstrong has hit the Hits Runs and RBIs Over in 14 of his last 20 games (+9.10 Units / 40% ROI)
  • Pete Crow-Armstrong has hit the Total Bases Over in 15 of his last 20 games (+8.35 Units / 29% ROI)
  • The Philadelphia Phillies have hit the Game Total Over in 8 of their last 10 games (+5.90 Units / 54% ROI)
  • The Philadelphia Phillies have hit the 1st Five Innings (F5) Team Total Under in 9 of their last 12 away games (+5.80 Units / 39% ROI)
  • The Philadelphia Phillies have hit the Team Total Under in 6 of their last 7 away games (+5.05 Units / 64% ROI)
  • The Philadelphia Phillies have covered the 1st Five Innings (F5) Run Line in 12 of their last 21 games (+1.85 Units / 7% ROI)
  • The Philadelphia Phillies have hit the 1st Five Innings (F5) Moneyline in 4 of their last 7 games (+1.40 Units / 10% ROI)
  • The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 18 of their last 22 games (+13.95 Units / 53% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 17 of their last 24 games (+12.05 Units / 39% ROI)
  • The Chicago Cubs have hit the Game Total Over in 15 of their last 21 games (+8.60 Units / 38% ROI)
  • The Chicago Cubs have hit the Team Total Over in 15 of their last 21 games (+8.55 Units / 35% ROI)
  • The Chicago Cubs have hit the Moneyline in 14 of their last 20 games (+7.85 Units / 31% ROI)

Phillies Against the Spread (ATS) Record

Against the spread this season, the Phillies are 13-12 against the Run Line (-1.8 Units / -5.62% ROI).

  • 13-12 when betting on the Moneyline for -3 Units / -7.34% ROI
  • 12-13 when betting on the total runs Over for -2.2 Units / -8% ROI
  • 13-12 when betting on the total runs Under for -0.1 Units / -0.36% ROI

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 14-12 against the Run Line (+3.1 Units / 9.44% ROI).

  • 16-10 when betting on the Moneyline for +5.75 Units / 18.25% ROI
  • 17-8 when betting on the total runs Over for +8.55 Units / 30.48% ROI
  • 8-17 when betting on the total runs Under for -10.9 Units / -37.39% ROI

Cubs vs Phillies Home Run Prop Bets Today

Over Under
Kyle Schwarber (PHI) 0.5 +300 0.5 -400
Kyle Tucker (CHC) 0.5 +400 0.5 -550
Bryce Harper (PHI) 0.5 +450 0.5 -625
Michael Busch (CHC) 0.5 +500 0.5 -700
Seiya Suzuki (CHC) 0.5 +525 0.5 -750

Cubs vs Phillies Total Hits Prop Bets Today

Over Under
Kyle Tucker (CHC) 0.5 -235 0.5 +180
Nico Hoerner (CHC) 0.5 -235 0.5 +175
Bryce Harper (PHI) 0.5 -225 0.5 +170
Bryson Stott (PHI) 0.5 -225 0.5 +170
Ian Happ (CHC) 0.5 -220 0.5 +165

Cubs vs Phillies RBI Prop Bets Today

Over Under
Bryce Harper (PHI) 0.5 +140 0.5 -190
Kyle Schwarber (PHI) 0.5 +145 0.5 -190
Kyle Tucker (CHC) 0.5 +150 0.5 -200
Seiya Suzuki (CHC) 0.5 +155 0.5 -200
Michael Busch (CHC) 0.5 +160 0.5 -210

Cubs vs Phillies Strikeout Prop Bets Today

Over Under
Colin Rea (CHC) 3.5 -160 3.5 +125

Opponents had a swing rate of just 30% (95/312) against Taijuan Walker on low breaking pitches in 2023 — lowest in MLB among starting pitchers with at least 64 total IP; League Avg: 46% — 0 Percentile.

Taijuan Walker had a strike rate of just 61% (1,722/2,837) in 2023 — 2nd lowest among qualified SPs in MLB; League Avg: 65% — fourth Percentile.

Taijuan Walker had a strike rate of just 58% (457/788) in two strike counts in 2023 — lowest among qualified SPs in MLB; League Avg: 64% — second Percentile.

Taijuan Walker has allowed a slugging percentage of .544 (224 Total Bases / 412 ABs) since last season — 2nd highest in MLB among starting pitchers with at least 74 total IP; League Avg: .402 — first Percentile.

Cubs Starting Pitcher Stats & Trends

Colin Rea walked 12 of 270 batters (4%) when going through the lineup the second time in a game in the 2024 season — 4th best among qualified SPs in MLB; League Avg: 7% — 94th Percentile.

Opponents had a two strike miss rate of just 21% (91/437) against Colin Rea in the 2024 season — tied for 5th lowest among qualified SPs in MLB; League Avg: 25% — 10th Percentile.

Opponents had a miss rate of just 20% (48/236) against Colin Rea on the first pitch of at-bats in the 2024 season — 9th lowest among qualified SPs in MLB; League Avg: 26% — 15th Percentile.

Opponents had a miss rate of just 19% (240/1,241) against Colin Rea in the 2024 season — 2nd lowest among qualified SPs in MLB; League Avg: 26% — third Percentile.

Phillies Keys to the Game vs. the Cubs

The Phillies are 3-8 (.273) when trailing entering the 7th inning this season — 3rd best in MLB; League Avg: .122.

The Phillies are 32-1 (.970) when they’ve had 5 or more XBH since last season — best in MLB; League Avg: .811.

The Phillies are just 14-23 (.378) when tied entering the 7th inning since the 2023 season — 3rd lowest in MLB; League Avg: .499.

The Phillies are just 0-9 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .038.

Cubs Keys to the Game vs. the Phillies

The Cubs are 1-8 (.111) when trailing entering the 9th inning this season — tied for 3rd best in MLB; League Avg: .038.

The Cubs are 8-5 (.615) on the road this season — tied for 2nd best in MLB; League Avg: .387.

The Cubs were 32-10 (.762) when they scored in the first inning in the 2024 season — 3rd best in MLB; League Avg: .641.

The Cubs are 10-1 (.909) when they’ve had 10 or more hits this season — 3rd best in MLB; League Avg: .750.

Phillies hitters have an OBP of .343 (2,230 PA’s) against LHP since last season — 2nd best in MLB; League Avg: .313.

The Phillies are batting .272 against LHP since last season — 2nd best in MLB; League Avg: .244.

The Phillies are batting .212 with two-strikes this season — best in MLB; League Avg: .167.

The Phillies batted .307 when facing the starting pitcher for the 3rd time in a game in the 2024 season — tied for best in MLB; League Avg: .263.

Cubs hitters have an OPS of .971 (166 PA’s) against LHP this month (16 games) — best in MLB; League Avg: .674.

Cubs hitters are slugging .538 against LHP this season — best in MLB; League Avg: .371.

Cubs hitters are slugging .551 against LHP this month (16 games) — best in MLB; League Avg: .367.

Cubs hitters have an OPS of .922 (229 PA’s) against LHP this season — best in MLB; League Avg: .678.

Opponents had a groundball rate of 46% against Phillies pitchers in the 2024 season — 2nd highest in MLB; League Avg: 43%.

Opponents had a groundball batting average of just .238 against Phillies pitchers with runners on base in the 2024 season — tied for 2nd best in MLB; League Avg: .262.

The Phillies have won 56% of home games in which their opponents scored first since the 2023 season — highest in MLB; League Avg: 37%.

Phillies pitchers have walked 7% of batters since last season — tied for 4th best in MLB; League Avg: 8%.

Cubs pitchers have walked 9% of batters when facing the leadoff batter in the inning since last season — tied for highest in MLB; League Avg: 8%.

Batters facing the Cubs pitchers have struck out in the zone 43% of the time this season — 2nd lowest in MLB; League Avg: 51%. this season — 2nd lowest in MLB; League Avg: 51%.

Cubs pitchers had an ERA of 3.08 (733.0 IP) at home in the 2024 season — 2nd best in MLB; League Avg: 3.98.

Batters facing the Cubs pitchers have struck out in the zone 48% of the time since the 2023 season — tied for 3rd lowest in MLB; League Avg: 49%. since the 2023 season — tied for 3rd lowest in MLB; League Avg: 49%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.