- The Cardinals are -145 favorites vs the Pirates
- Pirates vs Cardinals Over / Under today: 8.5 Runs
- Pirates / Cardinals TV Channel: FDMW | SNPT
The Pittsburgh Pirates (+120) visit Busch Stadium to take on the St. Louis Cardinals (-145) on Monday, May 5, 2025. First pitch is scheduled for 7:45pm EDT in St. Louis, MO.
This season, the Pirates are 12-23 against the spread (ATS), while the Cardinals are 17-18 ATS.
Pirates vs Cardinals Starting Pitchers Today:
- Pirates starting pitcher: Carmen Mlodzinski 1-3, 6.67 ERA
- Cardinals starting pitcher: Miles Mikolas 1-2, 4.61 ERA
Pirates vs. Cardinals Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Pirates | +1.5 -185 | O 8.5 -115 | +120 |
| Cardinals | -1.5 +150 | U 8.5 -105 | -145 |
Pirates vs Cardinals Prediction for Today’s Game
Based on recent trends the model predicts the Cardinals will win Monday‘s MLB game with 57.9% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
Bet now on Pirates vs Cardinals and all games with BetMGM
We’ve highlighted some favorite MLB player prop bets for Pirates players for Monday‘s game, looking at profitable historical betting trends:
Best Pirates Player Prop Bets Today:
- Ke’Bryan Hayes has hit the Runs Under in 19 of his last 20 games (+17.40 Units / 44% ROI)
- Andrew McCutchen has hit the Home Runs Over in 3 of his last 8 away games (+12.80 Units / 160% ROI)
- Bryan Reynolds has hit the Hits Runs and RBIs Under in 19 of his last 25 away games (+12.45 Units / 40% ROI)
- Ke’Bryan Hayes has hit the Singles Over in 13 of his last 15 games (+10.45 Units / 59% ROI)
- Ke’Bryan Hayes has hit the Hits Over in 13 of his last 15 games (+8.50 Units / 28% ROI)
And here are some favorite MLB player prop bets for Cardinals players for Monday‘s game, looking at profitable historical betting trends:
Best Cardinals Player Prop Best Bets Today:
- Brendan Donovan has hit the Hits Over in 20 of his last 25 games (+11.55 Units / 22% ROI)
- Lars Nootbaar has hit the Total Bases Over in 13 of his last 15 games at home (+10.55 Units / 44% ROI)
- Willson Contreras has hit the Singles Over in 12 of his last 15 games (+10.35 Units / 67% ROI)
- Victor Scott II has hit the Hits Runs and RBIs Over in 11 of his last 15 games at home (+6.75 Units / 32% ROI)
- Alec Burleson has hit the Runs Under in 12 of his last 15 games (+6.20 Units / 19% ROI)
Pirates Best Bets Today:
- The Pittsburgh Pirates have hit the Team Total Under in 11 of their last 15 away games (+6.65 Units / 39% ROI)
- The Pittsburgh Pirates have hit the 1st Five Innings (F5) Team Total Over in their last 6 away games (+6.55 Units / 90% ROI)
- The Pittsburgh Pirates have covered the 1st Five Innings (F5) Run Line in 5 of their last 6 away games (+4.10 Units / 62% ROI)
- The Pittsburgh Pirates have hit the 1st Five Innings (F5) Moneyline in 3 of their last 6 away games (+3.00 Units / 50% ROI)
- The Pittsburgh Pirates have covered the Run Line in 4 of their last 6 away games (+2.00 Units / 26% ROI)
Cardinals Best Bets Today:
- The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 13 of their last 18 games at home (+7.50 Units / 34% ROI)
- The St. Louis Cardinals have hit the Moneyline in 9 of their last 13 games at home (+5.85 Units / 40% ROI)
- The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 10 of their last 18 games at home (+5.70 Units / 26% ROI)
- The St. Louis Cardinals have hit the Game Total Over in their last 7 games (+4.00 Units / 52% ROI)
- The St. Louis Cardinals have covered the Run Line in 4 of their last 6 games (+1.35 Units / 16% ROI)
Pirates Against the Spread (ATS) Record
Against the spread this season, the Pirates are 12-23 against the Run Line (-15.25 Units / -33.85% ROI).
- 12-23 when betting on the Moneyline for -11.25 Units / -27.99% ROI
- 15-18 when betting on the total runs Over for -4.5 Units / -8.16% ROI
- 18-15 when betting on the total runs Under for +1.65 Units / 2.93% ROI
Cardinals Against the Spread (ATS) Record
Against the spread this season, the Cardinals are 17-18 against the Run Line (-6.8 Units / -13.43% ROI).
- 16-19 when betting on the Moneyline for -3 Units / -7.77% ROI
- 20-13 when betting on the total runs Over for +5.65 Units / 10.17% ROI
- 13-20 when betting on the total runs Under for -9.25 Units / -16.57% ROI
Cardinals vs Pirates Home Run Prop Bets Today
| Over | Under | |
|---|---|---|
| Oneil Cruz (PIT) | 0.5 +325 | 0.5 -450 |
| Nolan Gorman (STL) | 0.5 +450 | 0.5 -625 |
| Andrew McCutchen (PIT) | 0.5 +525 | 0.5 -750 |
| Bryan Reynolds (PIT) | 0.5 +625 | 0.5 -1000 |
| Willson Contreras (STL) | 0.5 +625 | 0.5 -1000 |
Cardinals vs Pirates Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Bryan Reynolds (PIT) | 0.5 -250 | 0.5 +190 |
| Lars Nootbaar (STL) | 0.5 -250 | 0.5 +180 |
| Alec Burleson (STL) | 0.5 -250 | 0.5 +185 |
| Nolan Arenado (STL) | 0.5 -225 | 0.5 +170 |
| Andrew McCutchen (PIT) | 0.5 -220 | 0.5 +165 |
Cardinals vs Pirates RBI Prop Bets Today
| Over | Under | |
|---|---|---|
| Oneil Cruz (PIT) | 0.5 +150 | 0.5 -200 |
| Andrew McCutchen (PIT) | 0.5 +155 | 0.5 -210 |
| Willson Contreras (STL) | 0.5 +160 | 0.5 -210 |
| Alec Burleson (STL) | 0.5 +160 | 0.5 -210 |
| Nolan Gorman (STL) | 0.5 +170 | 0.5 -225 |
Cardinals vs Pirates Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Miles Mikolas (STL) | 3.5 -120 | 3.5 -105 |
| Carmen Mlodzinski (PIT) | 3.5 +100 | 3.5 -135 |
Pirates Starting Pitcher Stats & Trends
Opponents are hitting .460 (23-for-50) against Carmen Mlodzinski when going through the lineup the second time in a game this season — highest in MLB among starting pitchers with at least 13 total IP; League Avg: .239 — 0 Percentile.
Carmen Mlodzinski has allowed an OPS of 1.160 (54 PA’s) when going through the lineup the second time in a game this season — 2nd highest in MLB among starting pitchers with at least 13 total IP; League Avg: .686 — first Percentile.
Carmen Mlodzinski has allowed an OBP of .500 (54 PA’s) when going through the lineup the second time in a game this season — highest in MLB among starting pitchers with at least 13 total IP; League Avg: .302 — 0 Percentile.
Carmen Mlodzinski has a strike rate of just 61% (637/1,044) against right-handed batters since the 2023 season — tied for 2nd lowest among NL Relievers; League Avg: 65% — third Percentile.
Cardinals Starting Pitcher Stats & Trends
Opponents had a two strike miss rate of just 14% (74/529) against Miles Mikolas in the 2024 season — lowest among qualified SPs in MLB; League Avg: 25% — first Percentile.
Opponents have a two strike miss rate of just 14% (86/611) against Miles Mikolas since last season — lowest among qualified SPs in MLB; League Avg: 25% — second Percentile.
Opponents batted .307 (104-for-339) against Miles Mikolas’ non-fastballs in the 2024 season — highest among qualified SPs in MLB; League Avg: .217 — first Percentile.
Miles Mikolas has allowed a slugging percentage of .367 (146 Total Bases / 398 ABs) with two-strikes since last season — 2nd highest among qualified SPs in MLB; League Avg: .249 — fourth Percentile.
Pirates Keys to the Game vs. the Cardinals
The Pirates are just 7-56 (.111) when allowing 10 or more hits since last season — 2nd lowest in MLB; League Avg: .252.
The Pirates are just 0-12 (.000) when allowing 10 or more hits this season — lowest in MLB; League Avg: .259.
The Pirates were just 7-44 (.137) when allowing 10 or more hits in the 2024 season — 2nd lowest in MLB; League Avg: .250.
The Pirates are just 12-23 (.343) this season — 3rd lowest in MLB; League Avg: .500.
Cardinals Keys to the Game vs. the Pirates
The Cardinals are just 53-59 (.473) vs bottom 10 scoring offenses since the 2023 season They play the Pirates (24th best runs scored) today.
The Cardinals are 30-21 (.588) when tied entering the 7th inning since the 2023 season — 3rd best in MLB; League Avg: .499.
The Cardinals were 69-1 (.986) when leading entering the 9th inning in the 2024 season — tied for 2nd best in MLB; League Avg: .949.
The Cardinals were 18-9 (.667) when tied entering the 7th inning in the 2024 season — tied for 3rd best in MLB; League Avg: .498.
Pirates Hitting Stats & Trends
The Pirates are batting just .111 on pitches out of the zone this season — lowest in MLB; League Avg: .150.
The Pirates have won just 43% of home games in which they have scored three or more runs in an inning this season — 2nd lowest in MLB; League Avg: 81%.
Pirates hitters are slugging just .508 on the first pitch of at-bats since the 2023 season — lowest in MLB; League Avg: .577.
Pirates hitters struck out 417 times in 1,598 PA’s (26%) against LHP in the 2024 season — 3rd highest in MLB; League Avg: 23%.
Cardinals Hitting Stats & Trends
The Cardinals are batting .212 on pitches out of the zone this season — best in MLB; League Avg: .150.
The Cardinals are batting .352 on changeups this season — best in MLB; League Avg: .236.
Cardinals hitters struck out just 351 times in 1,755 PA’s (20%) against LHP in the 2024 season — tied for 5th best in MLB; League Avg: 23%.
The Cardinals are batting .289 at home this season — best in MLB; League Avg: .250.
Pirates Pitching Stats & Trends
Batters facing the Pirates pitchers have struck out in the zone 52% of the time since last season — 2nd highest in MLB; League Avg: 50%. since last season — 2nd highest in MLB; League Avg: 50%.
Pirates pitchers have walked 7% of batters when facing the leadoff batter in the inning this season — 2nd best in MLB; League Avg: 9%.
Opponents have a miss rate of just 25% against Pirates pitchers since the 2023 season — 5th lowest in MLB; League Avg: 26%.
Pirates pitchers have won only 0% of games in which they have allowed their opponent to score in three different innings on the road since the 2023 season — tied for lowest in MLB; League Avg: 23%.
Cardinals Pitching Stats & Trends
Opponents had a miss rate of just 23% against Cardinals pitchers in 2023 — 2nd lowest in MLB; League Avg: 26%.
Opponents have a miss rate of just 23% against Cardinals pitchers since the 2023 season — 2nd lowest in MLB; League Avg: 26%.
Opponents have a miss rate of just 22% against Cardinals pitchers this season — lowest in MLB; League Avg: 25%.
Cardinals pitchers had a strikeout rate of just 38% with two-strikes in 2023 — tied for 2nd lowest in MLB; League Avg: 43%.
More MLB Reading:
Bet now on Pirates vs Cardinals and all games with BetMGM
Bet on MLB Odds at BetMGM
Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.
