Rays vs Diamondbacks Prediction, Odds & Player Prop Bets Today – MLB, Apr 22

Arizona Diamondbacks designated hitter Lourdes Gurriel Jr. bats during the third inning of a baseball game, Saturday, June 10, 2023, in Detroit.
(AP Photo/Carlos Osorio)
  • The Diamondbacks are -160 favorites vs the Rays
  • Rays vs Diamondbacks Over / Under today: 9 Runs
  • Rays / Diamondbacks TV Channel: DBTV | MLBN | FDFL

The Tampa Bay Rays (+135) visit Chase Field to take on the Arizona Diamondbacks (-160) on Tuesday, April 22, 2025. First pitch is scheduled for 9:40pm EDT in Phoenix, AZ, AZ.

This season, the Rays are 9-13 against the spread (ATS), while the Diamondbacks are 12-10 ATS.

Rays vs Diamondbacks Starting Pitchers Today:

  • Rays starting pitcher: Zack Littell 0-4, 5.48 ERA
  • Diamondbacks starting pitcher: Brandon Pfaadt 3-1, 3.13 ERA

Rays vs. Diamondbacks Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Rays+1.5 -165O 9 -115+135
Diamondbacks -1.5 +135U 9 -105-160

Rays vs Diamondbacks Prediction for Today’s Game

Based on recent trends the model predicts the Diamondbacks will win Tuesday‘s MLB game with 58.1% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Rays players for Tuesday‘s game, looking at profitable historical betting trends:

Best Rays Player Prop Bets Today:

  • Junior Caminero has hit the Home Runs Over in 4 of his last 9 games (+13.30 Units / 148% ROI)
  • Junior Caminero has hit the Hits Runs and RBIs Under in 19 of his last 25 away games (+11.75 Units / 37% ROI)
  • Jonathan Aranda has hit the Total Bases Over in 18 of his last 25 games (+11.50 Units / 33% ROI)
  • Junior Caminero has hit the Runs Under in 17 of his last 20 away games (+11.40 Units / 30% ROI)
  • Yandy Diaz has hit the Hits Under in his last 8 away games (+8.75 Units / 52% ROI)

And here are some favorite MLB player prop bets for Diamondbacks players for Tuesday‘s game, looking at profitable historical betting trends:

Best Diamondbacks Player Prop Best Bets Today:

  • Josh Naylor has hit the Home Runs Over in 4 of his last 10 games (+18.30 Units / 183% ROI)
  • Eugenio Suarez has hit the Singles Under in 18 of his last 20 games (+14.30 Units / 39% ROI)
  • Eugenio Suarez has hit the RBIs Under in 14 of his last 15 games (+12.85 Units / 41% ROI)
  • Eugenio Suarez has hit the Hits Runs and RBIs Under in 13 of his last 15 games (+10.70 Units / 58% ROI)
  • Eugenio Suarez has hit the Runs Under in 13 of his last 15 games (+10.50 Units / 44% ROI)
  • The Tampa Bay Rays have hit the 1st Five Innings (F5) Team Total Under in 14 of their last 22 games (+5.35 Units / 20% ROI)
  • The Tampa Bay Rays have hit the Team Total Under in 5 of their last 6 games (+3.70 Units / 50% ROI)
  • The Tampa Bay Rays have hit the Game Total Over in 7 of their last 12 games (+3.70 Units / 27% ROI)
  • The Tampa Bay Rays have covered the Run Line in 5 of their last 10 games (+0.75 Units / 6% ROI)
  • The Arizona Diamondbacks have hit the Team Total Over in 14 of their last 22 games (+4.95 Units / 19% ROI)
  • The Arizona Diamondbacks have hit the Moneyline in 8 of their last 11 games (+4.55 Units / 32% ROI)
  • The Arizona Diamondbacks have hit the 1st Five Innings (F5) Team Total Under in 7 of their last 9 games (+4.45 Units / 40% ROI)
  • The Arizona Diamondbacks have hit the Game Total Under in 4 of their last 6 games at home (+4.00 Units / 62% ROI)
  • The Arizona Diamondbacks have covered the Run Line in 12 of their last 21 games (+3.85 Units / 15% ROI)

Rays Against the Spread (ATS) Record

Against the spread this season, the Rays are 8-14 against the Run Line (-6.8 Units / -26.31% ROI).

  • 9-13 when betting on the Moneyline for -6.55 Units / -22.02% ROI
  • 9-11 when betting on the total runs Over for -3.05 Units / -12.45% ROI
  • 11-9 when betting on the total runs Under for +1.45 Units / 6.07% ROI

Diamondbacks Against the Spread (ATS) Record

Against the spread this season, the Diamondbacks are 12-10 against the Run Line (+2.85 Units / 10.63% ROI).

  • 13-9 when betting on the Moneyline for +2.05 Units / 7.21% ROI
  • 10-9 when betting on the total runs Over for +0.15 Units / 0.62% ROI
  • 9-10 when betting on the total runs Under for -2.2 Units / -9.03% ROI

Diamondbacks vs Rays Home Run Prop Bets Today

Over Under
Eugenio Suarez (ARI) 0.5 +290 0.5 -375
Corbin Carroll (ARI) 0.5 +310 0.5 -400
Pavin Smith (ARI) 0.5 +400 0.5 -525
Jonathan Aranda (TB) 0.5 +425 0.5 -600
Josh Naylor (ARI) 0.5 +500 0.5 -700

Diamondbacks vs Rays Total Hits Prop Bets Today

Over Under
Yandy Diaz (TB) 0.5 -275 0.5 +195
Lourdes Gurriel Jr. (ARI) 0.5 -235 0.5 +180
Jake Mangum (TB) 0.5 -235 0.5 +180
Josh Naylor (ARI) 0.5 -225 0.5 +170
Geraldo Perdomo (ARI) 0.5 -210 0.5 +155

Diamondbacks vs Rays RBI Prop Bets Today

Over Under
Corbin Carroll (ARI) 0.5 +140 0.5 -185
Eugenio Suarez (ARI) 0.5 +150 0.5 -200
Brandon Lowe (TB) 0.5 +155 0.5 -210
Pavin Smith (ARI) 0.5 +160 0.5 -210
Lourdes Gurriel Jr. (ARI) 0.5 +170 0.5 -220

Diamondbacks vs Rays Strikeout Prop Bets Today

Over Under
Brandon Pfaadt (ARI) 4.5 -160 4.5 +120
Zack Littell (TB) 3.5 -125 3.5 -105

Opponents have a miss rate of just 7% (2/31) against Zack Littell on the first pitch of at-bats this season — lowest among qualified SPs in MLB; League Avg: 25% — first Percentile.

Zack Littell has a strike rate of 74% (74/100) in two strike counts this season — tied for 2nd highest among qualified SPs in MLB; League Avg: 64% — 98th Percentile.

Zack Littell has a strike rate of 70% (237/337) this season — tied for highest among among AL Starters; League Avg: 64% — 100th Percentile.

Zack Littell has a strike rate of 70% (237/337) this season — tied for 3rd highest among qualified SPs in MLB; League Avg: 64% — 97th Percentile.

Diamondbacks Starting Pitcher Stats & Trends

Division opponents are hitting .305 (61-for-200) against Brandon Pfaadt since last season — 2nd highest among qualified SPs in MLB; League Avg: .232 — fourth Percentile.

Brandon Pfaadt has allowed a slugging percentage of .488 (21 Total Bases / 43 ABs) with two-strikes this season — 2nd highest among among NL Starters; League Avg: .248 — fourth Percentile.

Brandon Pfaadt has walked 5% of batters when going through the lineup the second time in a game since last season — tied for 5th best among qualified SPs in MLB; League Avg: 7% — 92nd Percentile.

Brandon Pfaadt has allowed a slugging percentage of .488 (21 Total Bases / 43 ABs) with two-strikes this season — 2nd highest among qualified SPs in MLB; League Avg: .247 — second Percentile.

Rays Keys to the Game vs. the Diamondbacks

The Rays are just 9-14 (.391) when tied entering the 8th inning since last season — 5th lowest in MLB; League Avg: .500.

The Rays are 78-47 (.619) vs bottom 10 scoring offenses since the 2023 season They play the Diamondbacks (first best runs scored) today.

The Rays are 13-137 (.086) when trailing entering the 9th inning since the 2023 season — tied for best in MLB; League Avg: .049.

The Rays are 90-65 (.577) after a loss since the 2023 season — 5th best in MLB; League Avg: .496.

Diamondbacks Keys to the Game vs. the Rays

The Diamondbacks are 3-9 (.250) when trailing entering the 8th inning this season — tied for best in MLB; League Avg: .082.

The Diamondbacks are 6-68 (.080) when trailing entering the 9th inning since last season — 3rd best in MLB; League Avg: .048.

The Diamondbacks were 67-15 (.807) when they allowed 4 or fewer runs in the 2024 season — 3rd best in MLB; League Avg: .723.

The Diamondbacks are 144-35 (.800) when allowing 4 or fewer runs since the 2023 season — 3rd best in MLB; League Avg: .727.

The Rays have not scored first in any of their road games this season — lowest in MLB; League Avg: 53%.

Rays hitters slugged just .366 at home in the 2024 season — 3rd lowest in MLB; League Avg: .404.

Rays hitters have put just 31% of their swings in play on the first pitch of at-bats since the 2023 season — lowest in MLB; League Avg: 35%.

Rays hitters had an OPS of just .657 (4,637 PA’s) against RHP in the 2024 season — 2nd lowest in MLB; League Avg: .711.

Diamondbacks hitters have struck out in just 14% of it’s PA’s against LHP this season — best in MLB; League Avg: 24%.

The Diamondbacks are batting .279 against LHP since last season — best in MLB; League Avg: .244.

Diamondbacks hitters have an OBP of .349 (3,462 PA’s) at home since last season — best in MLB; League Avg: .317.

The Diamondbacks batted .284 against LHP in the 2024 season — best in MLB; League Avg: .245.

Rays pitchers had a strikeout rate of 46% with two-strikes in 2023 — 2nd best in MLB; League Avg: 43%.

Rays pitchers walked 103 of 1,444 batters (7%) when facing the leadoff batter in the inning in 2023 — 5th best in MLB; League Avg: 8%.

Rays pitchers have a strikeout rate of 47% with two-strikes this season — 4th best in MLB; League Avg: 42%.

Rays pitchers have a strikeout rate of 26% this season — tied for 4th best in MLB; League Avg: 23%.

Opponents had a miss rate of just 24% against Diamondbacks pitchers in the 2024 season — tied for 4th lowest in MLB; League Avg: 25%.

Diamondbacks pitchers had a strikeout rate of just 21% in the 2024 season — 5th lowest in MLB; League Avg: 23%.

Batters facing the Diamondbacks pitchers have struck out in the zone 48% of the time since the 2023 season — tied for 4th lowest in MLB; League Avg: 49%. since the 2023 season — tied for 4th lowest in MLB; League Avg: 49%.

The Diamondbacks pitchers have allowed their opponents to score first in just 35% of their games on the road since the 2023 season — 2nd lowest in MLB; League Avg: 44%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.