Red Sox vs Pirates Prediction, Odds & Player Prop Bets Today – MLB, Apr 21

min read
Pirates player Andrew McCutchen smiling while running.
(AP Photo/Charles Rex Arbogast)
BetMGM Betting @BETMGM Apr 21, 2024, 11:01 AM
  • The Pirates are -150 favorites vs the Red Sox
  • Red Sox vs Pirates Over / Under today: 8.5 Runs
  • Red Sox / Pirates TV Channel: NESN | SNPT

The Boston Red Sox (+125) visit PNC Park to take on the Pittsburgh Pirates (-150) on Sunday, April 21, 2024. First pitch is scheduled for 1:35pm EDT in Pittsburgh, PA.

This season, the Red Sox are 12-10 against the spread (ATS), while the Pirates are 12-9 ATS.

Red Sox vs Pirates Starting Pitchers Today:

  • Red Sox starting pitcher: Josh Winckowski 1-1, 4.50 ERA
  • Pirates starting pitcher: Martin Perez 1-0, 2.56 ERA

Red Sox vs. Pirates Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Red Sox+1.5 -160O 8.5 -110+125
Pirates -1.5 +135U 8.5 -110-150

Red Sox vs Pirates Prediction for Today’s Game

Based on recent trends the model predicts the Pirates will win Sunday‘s MLB game with 55.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


Bet now on Red Sox vs Pirates and all games with BetMGM


We’ve highlighted some favorite MLB player prop bets for Red Sox players for Sunday‘s game, looking at profitable historical betting trends:

Best Red Sox Player Prop Bets Today:

  • Pablo Reyes has hit the Hits Under in 11 of his last 18 games (+8.70 Units / 48% ROI)
  • Pablo Reyes has hit the Total Bases Under in 10 of his last 13 games (+7.65 Units / 40% ROI)
  • Pablo Reyes has hit the Hits Runs and RBIs Under in 13 of his last 18 games (+6.35 Units / 26% ROI)
  • Brayan Bello has hit the Pitching Outs Over in 16 of his last 25 games (+6.10 Units / 20% ROI)
  • David Hamilton has hit the Hits Under in 12 of his last 19 games (+5.85 Units / 29% ROI)

And here are some favorite MLB player prop bets for Pirates players for Sunday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Best Bets Today:

  • Henry Davis has hit the Hits Runs and RBIs Under in 15 of his last 19 games (+10.50 Units / 40% ROI)
  • Henry Davis has hit the Total Bases Under in 11 of his last 13 games at home (+8.10 Units / 38% ROI)
  • Henry Davis has hit the Hits Under in 7 of his last 11 games at home (+5.15 Units / 47% ROI)
  • Alika Williams has hit the Total Bases Over in 6 of his last 7 games (+5.00 Units / 62% ROI)
  • Alika Williams has hit the Hits Over in 6 of his last 7 games (+4.95 Units / 61% ROI)
  • The Boston Red Sox have hit the Game Total Under in 15 of their last 19 games (+10.60 Units / 50% ROI)
  • The Boston Red Sox have hit the 1st Five Innings (F5) Team Total Under in 37 of their last 66 away games (+7.03 Units / 9% ROI)
  • The Boston Red Sox have hit the Team Total Under in 34 of their last 61 away games (+5.05 Units / 7% ROI)
  • The Boston Red Sox have covered the 1st Five Innings (F5) Run Line in 5 of their last 7 away games (+2.95 Units / 38% ROI)
  • The Boston Red Sox have hit the 1st Five Innings (F5) Moneyline in 3 of their last 6 away games (+1.53 Units / 24% ROI)
  • The Pittsburgh Pirates have hit the Moneyline in 35 of their last 67 games (+15.85 Units / 22% ROI)
  • The Pittsburgh Pirates have hit the Game Total Over in 69 of their last 120 games (+15.10 Units / 11% ROI)
  • The Pittsburgh Pirates have hit the Team Total Under in 76 of their last 134 games (+11.44 Units / 7% ROI)
  • The Pittsburgh Pirates have hit the 1st Five Innings (F5) Moneyline in 29 of their last 65 games (+10.67 Units / 15% ROI)
  • The Pittsburgh Pirates have covered the Run Line in 39 of their last 63 games (+10.50 Units / 13% ROI)

Red Sox Against the Spread (ATS) Record

Against the spread this season, the Red Sox are 13-9 against the Run Line (+3.75 Units / 12% ROI).

  • 12-10 when betting on the Moneyline for +1.1 Units / 4.25% ROI
  • 10-11 when betting on the total runs Over for -2.05 Units / -8.44% ROI
  • 11-10 when betting on the total runs Under for +0.05 Units / 0.21% ROI

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 12-9 against the Run Line (+1.1 Units / 3.72% ROI).

  • 11-10 when betting on the Moneyline for +1.65 Units / 7.19% ROI
  • 12-9 when betting on the total runs Over for +2.1 Units / 9.11% ROI
  • 9-12 when betting on the total runs Under for -4.25 Units / -18.36% ROI

Pirates vs Red Sox Home Run Prop Bets Today

Over Under
Bobby Dalbec (BOS) 0.5 +425 0.5 -600
Jack Suwinski (PIT) 0.5 +550 0.5 -800
Ceddanne Rafaela (BOS) 0.5 +625 0.5 -1000
Connor Wong (BOS) 0.5 +625 0.5 -1000
Bryan Reynolds (PIT) 0.5 +625 0.5 -1000

Pirates vs Red Sox Total Hits Prop Bets Today

Over Under
Ke'Bryan Hayes (PIT) 0.5 -250 0.5 +175
Rob Refsnyder (BOS) 0.5 -250 0.5 +190
Bryan Reynolds (PIT) 0.5 -225 0.5 +170
Ceddanne Rafaela (BOS) 0.5 -210 0.5 +155
Masataka Yoshida (BOS) 0.5 -210 0.5 +155

Pirates vs Red Sox RBI Prop Bets Today

Over Under
Ke'Bryan Hayes (PIT) 0.5 +165 0.5 -225
Bobby Dalbec (BOS) 0.5 +165 0.5 -225
Jack Suwinski (PIT) 0.5 +170 0.5 -225
Rob Refsnyder (BOS) 0.5 +170 0.5 -225
Ceddanne Rafaela (BOS) 0.5 +175 0.5 -250

Opponents are hitting just .130 against Josh Winckowski vs right-handed batters this season — tied for eighth best among qualified RPs– 93rd Percentile. Right handed batters hit .287 (56-for-195) against him last season — 10th worst among qualified RPs– 10th Percentile.

Left-handed batters are hitting .481 (13-for-27) against Josh Winckowski this season — highest among qualified RPs in MLB; League Avg: .229 — 0 Percentile.

Josh Winckowski allowed a batting average of just .130 vs right-handed batters (tied for eighth best)– 93rd Percentile and .481 vs left-handed batters this season (worst among qualified RPs)– 0 Percentile.

Opponents are hitting .285 (190-for-666) against Josh Winckowski since the 2022 season — 5th highest among qualified RPs in MLB*; League Avg: .230 — second Percentile.

Pirates Starting Pitcher Stats & Trends

Martin Perez has located his fastball inside 62% of the time (87/141) this season — 2nd highest among qualified SPs in MLB; League Avg: 34% — 98th Percentile.

Martin Perez has located his fastball inside 62% of the time (87/141) this season — highest among in NL; League Avg: 35% — 100th Percentile.

Martin Perez has located his fastball inside 62% of the time (87/141) this season — highest among in NL; League Avg: 35% — 100th Percentile.

Martin Perez has thrown inside pitches 47% of the time (42/90) with two-strikes this season — highest among in NL; League Avg: 31% — 100th Percentile.

Red Sox Keys to the Game vs. the Pirates

The Red Sox are just 19-31 (.380) after a home loss since the 2023 season — 3rd lowest in MLB; League Avg: .509.

The Red Sox are just 1-81 (.012) when trailing entering the 9th inning since the 2023 season — 2nd lowest in MLB; League Avg: .052.

The Red Sox are just 35-65 (.350) after a loss as underdogs since the 2022 season — 3rd lowest in MLB; League Avg: .409.

The Red Sox are just 3-147 (.020) when trailing entering the 9th inning since the 2022 season — 3rd lowest in MLB; League Avg: .049.

Pirates Keys to the Game vs. the Red Sox

The Pirates are just 49-168 (.226) when scoring 4 or fewer runs since the 2022 season — 5th lowest in MLB; League Avg: .280.

The Pirates are 15-8 (.652) after a loss as favorites since the 2022 season — 4th best in MLB; League Avg: .589.

The Pirates are just 12-19 (.387) when tied entering the 8th inning since the 2022 season — 3rd lowest in MLB; League Avg: .500.

The Pirates are just 120-61 (.663) when allowing 4 or fewer runs since the 2022 season — tied for 3rd lowest in MLB; League Avg: .720.

Red Sox hitters are slugging .800 on the first pitch of at-bats this season — 2nd best in MLB; League Avg: .559.

Red Sox hitters have an OPS of .749 (5,220 PA’s) against RHP since last season — 5th best in MLB; League Avg: .728.

The Red Sox are batting .288 with two outs this season — best in MLB; League Avg: .230.

The Red Sox are batting .177 on pitches out of the zone since last season — 2nd best in MLB; League Avg: .152.

The Pirates are batting just .233 against LHP since the 2022 season — 2nd lowest in MLB; League Avg: .249.

Pirates hitters have 381 strikeouts in 1,128 PA’s (34%) in lefty-lefty matchups since the 2022 season — highest in MLB; League Avg: 24%.

Pirates hitters are slugging just .178 on pitches out of the zone since the 2022 season — 2nd lowest in MLB; League Avg: .213.

Pirates hitters have 72 strikeouts in 260 PA’s (28%) against LHP this season — 5th highest in MLB; League Avg: 22%.

Red Sox pitchers have an ERA of 1.50 (108.1 IP) on the road this season — best in MLB; League Avg: 4.08.

Red Sox pitchers have a strikeout rate of 33% when going through the lineup the third time in a game this season — best in MLB; League Avg: 19%.

Opponents have a groundball rate of 45% against Red Sox pitchers since last season — tied for 5th highest in MLB; League Avg: 43%.

Red Sox pitchers have a strikeout rate of 25% this season — tied for 5th best in MLB; League Avg: 23%.

Pirates pitchers are throwing just 3.61 pitches per plate appearance this season — lowest in MLB; League Avg: 3.92.

Pirates pitchers have a strikeout rate of 44% with two-strikes this season — 5th best in MLB; League Avg: 42%.

The Pirates have won 42% of road games in which their opponents scored first since last season — 5th highest in MLB; League Avg: 30%.

Pirates pitchers have walked 1,244 of 13,297 batters (9%) since the 2022 season — 5th highest in MLB; League Avg: 8%.

Pirates vs. Red Sox Injuries Tonight That May Affect Prop Bets 

  • Miguel Andujar (Pittsburgh Pirates): Knee, 10-Day IL
  • Colin Holderman (Pittsburgh Pirates): Illness, 15-Day IL
  • Johan Oviedo (Pittsburgh Pirates): Elbow, 60-Day IL
  • Dauri Moreta (Pittsburgh Pirates): Elbow, 60-Day IL
  • Carmen Mlodzinski (Pittsburgh Pirates): Elbow, 15-Day IL
  • Vince Velasquez (Pittsburgh Pirates): Elbow, Out
  • Mike Burrows (Pittsburgh Pirates): Elbow, Out
  • JT Brubaker (Pittsburgh Pirates): Elbow, 60-Day IL
  • Max Kranick (Pittsburgh Pirates): Hamstring, 15-Day IL
  • Endy Rodriguez (Pittsburgh Pirates): Elbow, 60-Day IL
  • Ji Hwan Bae (Pittsburgh Pirates): Hip, 10-Day IL
  • Wyatt Mills (Boston Red Sox): Elbow, 60-Day IL
  • Vaughn Grissom (Boston Red Sox): Hamstring, 10-Day IL
  • Michael Fulmer (Boston Red Sox): Elbow, 60-Day IL
  • Zack Kelly (Boston Red Sox): Oblique, Day-To-Day
  • Bryan Mata (Boston Red Sox): Hamstring, 15-Day IL
  • Chris Murphy (Boston Red Sox): Elbow, 60-Day IL
  • Kenley Jansen (Boston Red Sox): Back, Day-To-Day
  • Brandon Walter (Boston Red Sox): Shoulder, 7-Day IL
  • Lucas Giolito (Boston Red Sox): Elbow, 60-Day IL
  • Rob Refsnyder (Boston Red Sox): Toe, 10-Day IL
  • Yu Chang (Boston Red Sox): Oblique, Out

Bet now on Red Sox vs Pirates and all games with BetMGM


Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.

First Bet Offer BetMGM State Promo Pages $1,500
About the Author

BetMGM Betting

Read More @BETMGM

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.