Reds vs Guardians Prediction, Odds & Player Prop Bets Today – MLB, Jun 10

(AP Photo/Ryan Sun)
  • The Reds are -105 favorites vs the Guardians
  • Reds vs Guardians Over / Under today: 8 Runs
  • Reds / Guardians TV Channel: FDOH | GDTV

The Cincinnati Reds (-105) visit Progressive Field to take on the Cleveland Guardians (-115) on Tuesday, June 10, 2025. First pitch is scheduled for 6:40pm EDT in Cleveland, OH, OH.

This season, the Reds are 34-33 against the spread (ATS), while the Guardians are 33-32 ATS.

Reds vs Guardians Starting Pitchers Today:

  • Reds starting pitcher: Andrew Abbott 5-1, 2.18 ERA
  • Guardians starting pitcher: Slade Cecconi 1-2, 4.95 ERA

Reds vs. Guardians Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Reds-1.5 +155O 8 -105-105
Guardians +1.5 -190U 8 -115-115

Reds vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Tuesday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Reds players for Tuesday‘s game, looking at profitable historical betting trends:

Best Reds Player Prop Bets Today:

  • Tyler Stephenson has hit the Home Runs Over in 3 of his last 7 away games (+15.30 Units / 219% ROI)
  • Gavin Lux has hit the Hits Over in 16 of his last 20 away games (+10.80 Units / 31% ROI)
  • Matt McLain has hit the Runs Under in 13 of his last 15 away games (+10.15 Units / 36% ROI)
  • Gavin Lux has hit the Singles Over in 17 of his last 25 away games (+9.05 Units / 32% ROI)
  • Matt McLain has hit the Hits Runs and RBIs Under in 12 of his last 15 away games (+8.60 Units / 41% ROI)

And here are some favorite MLB player prop bets for Guardians players for Tuesday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Best Bets Today:

  • Jose Ramirez has hit the Singles Over in 19 of his last 25 games at home (+13.70 Units / 51% ROI)
  • Jose Ramirez has hit the Home Runs Over in 3 of his last 6 games at home (+10.80 Units / 180% ROI)
  • Steven Kwan has hit the Runs Under in 16 of his last 20 games at home (+10.35 Units / 36% ROI)
  • Steven Kwan has hit the Hits Runs and RBIs Under in 14 of his last 20 games at home (+8.55 Units / 39% ROI)
  • Angel Martinez has hit the Hits Under in 9 of his last 15 games (+7.90 Units / 48% ROI)
  • The Cincinnati Reds have hit the Game Total Under in 29 of their last 44 games (+12.40 Units / 25% ROI)
  • The Cincinnati Reds have covered the Run Line in 37 of their last 64 games (+6.75 Units / 8% ROI)
  • The Cincinnati Reds have hit the 1st Five Innings (F5) Team Total Under in 20 of their last 33 games (+5.70 Units / 15% ROI)
  • The Cincinnati Reds have hit the Team Total Under in 8 of their last 11 games (+5.00 Units / 38% ROI)
  • The Cincinnati Reds have covered the 1st Five Innings (F5) Run Line in 32 of their last 57 games (+4.75 Units / 7% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Under in 15 of their last 21 games at home (+8.80 Units / 34% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 18 of their last 28 games (+8.05 Units / 25% ROI)
  • The Cleveland Guardians have hit the Moneyline in 31 of their last 56 games (+6.75 Units / 10% ROI)
  • The Cleveland Guardians have hit the Team Total Under in 16 of their last 25 games at home (+6.14 Units / 21% ROI)
  • The Cleveland Guardians have covered the Run Line in 11 of their last 19 games (+1.85 Units / 7% ROI)

Reds Against the Spread (ATS) Record

Against the spread this season, the Reds are 37-29 against the Run Line (+2.4 Units / 2.58% ROI).

  • 34-33 when betting on the Moneyline for -2.65 Units / -3.28% ROI
  • 27-39 when betting on the total runs Over for -15.4 Units / -21.02% ROI
  • 39-27 when betting on the total runs Under for +9.35 Units / 12.61% ROI

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 33-32 against the Run Line (-4.25 Units / -4.74% ROI).

  • 34-31 when betting on the Moneyline for +3.6 Units / 4.76% ROI
  • 29-33 when betting on the total runs Over for -6.15 Units / -8.74% ROI
  • 33-29 when betting on the total runs Under for +1.15 Units / 1.58% ROI

Guardians vs Reds Home Run Prop Bets Today

Over Under
Christian Encarnacion-Strand (CIN) 0.5 +375 0.5 -500
Jose Ramirez (CLE) 0.5 +400 0.5 -550
Elly De La Cruz (CIN) 0.5 +425 0.5 -550
Will Benson (CIN) 0.5 +450 0.5 -625
David Fry (CLE) 0.5 +500 0.5 -700

Guardians vs Reds Total Hits Prop Bets Today

Over Under
Christian Encarnacion-Strand (CIN) 0.5 -275 0.5 +195
Jose Ramirez (CLE) 0.5 -275 0.5 +210
Steven Kwan (CLE) 0.5 -250 0.5 +185
Elly De La Cruz (CIN) 0.5 -235 0.5 +175
TJ Friedl (CIN) 0.5 -220 0.5 +165

Guardians vs Reds RBI Prop Bets Today

Over Under
Christian Encarnacion-Strand (CIN) 0.5 +125 0.5 -160
Jose Ramirez (CLE) 0.5 +130 0.5 -175
Elly De La Cruz (CIN) 0.5 +150 0.5 -200
David Fry (CLE) 0.5 +165 0.5 -220
Tyler Stephenson (CIN) 0.5 +185 0.5 -250

Guardians vs Reds Strikeout Prop Bets Today

Over Under
Slade Cecconi (ARI) 4.5 -155 4.5 +115
Andrew Abbott (CIN) 4.5 -145 4.5 +110

Opponents had a groundball rate of just 22% (10/46) against Andrew Abbott on low breaking pitches in 2023 — lowest in MLB among starting pitchers with at least 64 total IP; League Avg: 49% — 0 Percentile.

Andrew Abbott has allowed a SLG of just .173 on non-fastballs down this season — tied for ninth best among starting pitchers with at least 25 total IP– 93rd Percentile. He allowed a SLG of .444 on low non-fastballs last season — tied for sixth worst among starting pitchers with at least 64 total IP– fifth Percentile.

Opponents have a groundball rate of just 27% (35/128) against Andrew Abbott’s low breaking balls since the 2023 season — lowest in MLB among starting pitchers with at least 154 total IP; League Avg: 48% — first Percentile.

Opponents had a groundball rate of just 20% (21/103) against Andrew Abbott’s curve and slider in 2023 — lowest in MLB among starting pitchers with at least 64 total IP; League Avg: 43% — 0 Percentile.

Guardians Starting Pitcher Stats & Trends

Slade Cecconi has an ERA of 6.29 (97.1 IP)since last season — 2nd highest in MLB among starting pitchers with at least 90 total IP; League Avg: 3.92 — first Percentile.

Slade Cecconi has allowed a slugging percentage of .533 (210 Total Bases / 394 ABs) since last season — highest in MLB among starting pitchers with at least 90 total IP; League Avg: .401 — 0 Percentile.

Slade Cecconi has allowed at least one HR in each of his last four games dating back to May 17th — the longest active streak is 5.

Slade Cecconi has thrown 56% of his pitches in the strike zone (915/1,620) since last season — 4th best in MLB among starting pitchers with at least 90 total IP; League Avg: 50% — 98th Percentile.

Reds Keys to the Game vs. the Guardians

The Reds are just 15-29 (.341) when tied entering the 8th inning since the 2023 season — 2nd lowest in MLB; League Avg: .500.

The Reds were just 5-16 (.238) when tied entering the 8th inning in the 2024 season — lowest in MLB; League Avg: .500.

The Reds are just 0-27 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .043.

The Reds are just 6-86 (.065) when trailing entering the 7th inning since last season — 2nd lowest in MLB; League Avg: .141.

Guardians Keys to the Game vs. the Reds

The Guardians are 15-0 (.938) when they’ve had 10 or more hits this season — best in MLB; League Avg: .734.

The Guardians are 98-3 (.970) when leading entering the 7th inning since last season — best in MLB; League Avg: .858.

The Guardians were just 3-61 (.047) when trailing entering the 8th inning in the 2024 season — 2nd lowest in MLB; League Avg: .100.

The Guardians are 27-0 (1.000) when leading entering the 8th inning this season — tied for best in MLB; League Avg: .904.

The Reds are batting just .129 on pitches out of the zone since the 2023 season — tied for lowest in MLB; League Avg: .150.

Reds hitters slugged just .151 on pitches out of the zone in the 2024 season — lowest in MLB; League Avg: .204.

The Reds are batting just .223 against LHP since last season — 3rd lowest in MLB; League Avg: .243.

The Reds batted just .226 against LHP in the 2024 season — 3rd lowest in MLB; League Avg: .245.

Guardians hitters struck out just 791 times in 4,186 PA’s (19%) against RHP in 2023 — best in MLB; League Avg: 23%.

Guardians hitters have struck out in 30% of it’s PA’s in righty-righty matchups this season — highest in MLB; League Avg: 22%.

Guardians hitters have put just 34% of balls in play to the left side of the field since the 2023 season — lowest in MLB; League Avg: 38%.

The Guardians are batting just .297 in hitter’s counts since last season — lowest in MLB; League Avg: .336.

Opponents have a groundball rate of just 39% against Reds pitchers since the 2023 season — lowest in MLB; League Avg: 43%.

Opponents have a groundball rate of just 38% against Reds pitchers this season — 2nd lowest in MLB; League Avg: 43%.

Opponents had a groundball rate of just 39% against Reds pitchers in 2023 — 2nd lowest in MLB; League Avg: 43%.

Opponents had a groundball rate of just 39% against Reds pitchers in the 2024 season — lowest in MLB; League Avg: 43%.

Opponents had a groundball batting average of just .207 against Guardians pitchers with runners on base in the 2024 season — best in MLB; League Avg: .262.

The Guardians allowed 0.87 runs per game (140/161) in late innings in the 2024 season — best in MLB; League Avg: 1.29.

Opponents had a groundball batting average of just .223 against Guardians pitchers in the 2024 season — best in MLB; League Avg: .249.

Opponents have a groundball rate of just 40% against Guardians pitchers this season — 5th lowest in MLB; League Avg: 43%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.