- The Reds are -125 favorites vs the Pirates
- Reds vs Pirates Over / Under today: 8 Runs
- Reds / Pirates TV Channel: FDOH | SNPT
The Cincinnati Reds (-130) visit PNC Park to take on the Pittsburgh Pirates (+110) on Wednesday, May 21, 2025. First pitch is scheduled for 12:35pm EDT in Pittsburgh, PA, PA.
This season, the Reds are 25-25 against the spread (ATS), while the Pirates are 19-30 ATS.
Reds vs Pirates Starting Pitchers Today:
- Reds starting pitcher: Brady Singer 5-2, 5.05 ERA
- Pirates starting pitcher: Andrew Heaney 2-3, 3.04 ERA
Reds vs. Pirates Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Reds | -1.5 +135 | O 8 -115 | -130 |
| Pirates | +1.5 -160 | U 8 -105 | +110 |
Reds vs Pirates Prediction for Today’s Game
Based on recent trends the model predicts the Reds will win Wednesday‘s MLB game with 53.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
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We’ve highlighted some favorite MLB player prop bets for Reds players for Wednesday‘s game, looking at profitable historical betting trends:
Best Reds Player Prop Bets Today:
- Matt McLain has hit the Runs Under in 19 of his last 25 games (+11.35 Units / 31% ROI)
- Spencer Steer has hit the Hits Over in 19 of his last 25 games (+9.00 Units / 20% ROI)
- Matt McLain has hit the Hits Runs and RBIs Under in 17 of his last 25 games (+7.95 Units / 25% ROI)
- Elly De La Cruz has hit the Home Runs Over in 3 of his last 10 games (+6.90 Units / 69% ROI)
- Elly De La Cruz has hit the Singles Under in his last 6 away games (+6.00 Units / 70% ROI)
And here are some favorite MLB player prop bets for Pirates players for Wednesday‘s game, looking at profitable historical betting trends:
Best Pirates Player Prop Best Bets Today:
- Jared Triolo has hit the Home Runs Over in 2 of his last 9 games (+15.00 Units / 167% ROI)
- Jared Triolo has hit the Singles Under in 18 of his last 20 games (+14.35 Units / 41% ROI)
- Ke’Bryan Hayes has hit the Runs Under in 14 of his last 15 games at home (+12.30 Units / 45% ROI)
- Oneil Cruz has hit the Hits Under in 11 of his last 15 games (+10.95 Units / 57% ROI)
- Jared Triolo has hit the Hits Runs and RBIs Under in 12 of his last 15 games at home (+9.95 Units / 51% ROI)
Reds Best Bets Today:
- The Cincinnati Reds have hit the Game Total Under in 21 of their last 27 games (+14.10 Units / 47% ROI)
- The Cincinnati Reds have hit the 1st Five Innings (F5) Team Total Under in 12 of their last 16 games (+7.80 Units / 42% ROI)
- The Cincinnati Reds have covered the Run Line in 28 of their last 47 games (+5.60 Units / 9% ROI)
- The Cincinnati Reds have hit the Moneyline in 5 of their last 6 games (+3.55 Units / 42% ROI)
- The Cincinnati Reds have hit the 1st Five Innings (F5) Moneyline in 19 of their last 39 games (+3.45 Units / 6% ROI)
Pirates Best Bets Today:
- The Pittsburgh Pirates have hit the Team Total Under in 32 of their last 48 games (+14.30 Units / 25% ROI)
- The Pittsburgh Pirates have hit the Game Total Under in 24 of their last 37 games (+12.95 Units / 31% ROI)
- The Pittsburgh Pirates have hit the 1st Five Innings (F5) Team Total Under in 15 of their last 20 games at home (+10.05 Units / 42% ROI)
- The Pittsburgh Pirates have covered the 1st Five Innings (F5) Run Line in 4 of their last 5 games at home (+3.00 Units / 47% ROI)
- The Pittsburgh Pirates have covered the Run Line in 7 of their last 11 games (+2.60 Units / 20% ROI)
Reds Against the Spread (ATS) Record
Against the spread this season, the Reds are 28-22 against the Run Line (+1.25 Units / 1.81% ROI).
- 25-25 when betting on the Moneyline for -3.4 Units / -5.46% ROI
- 18-31 when betting on the total runs Over for -15.7 Units / -28.83% ROI
- 31-18 when betting on the total runs Under for +11.05 Units / 19.89% ROI
Pirates Against the Spread (ATS) Record
Against the spread this season, the Pirates are 19-30 against the Run Line (-16.9 Units / -27% ROI).
- 16-33 when betting on the Moneyline for -14.9 Units / -27.34% ROI
- 17-29 when betting on the total runs Over for -14.55 Units / -27.12% ROI
- 29-17 when betting on the total runs Under for +10.4 Units / 19.21% ROI
Pirates vs Reds Home Run Prop Bets Today
| Over | Under | |
|---|---|---|
| Oneil Cruz (PIT) | 0.5 +375 | 0.5 -500 |
| Austin Hays (CIN) | 0.5 +425 | 0.5 -600 |
| Tyler Stephenson (CIN) | 0.5 +450 | 0.5 -625 |
| Elly De La Cruz (CIN) | 0.5 +550 | 0.5 -800 |
| Spencer Steer (CIN) | 0.5 +550 | 0.5 -800 |
Pirates vs Reds Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Santiago Espinal (CIN) | 0.5 -250 | 0.5 +185 |
| Oneil Cruz (PIT) | 0.5 -235 | 0.5 +175 |
| Bryan Reynolds (PIT) | 0.5 -225 | 0.5 +170 |
| Austin Hays (CIN) | 0.5 -225 | 0.5 +175 |
| Isiah Kiner-Falefa (PIT) | 0.5 -220 | 0.5 +165 |
Pirates vs Reds RBI Prop Bets Today
| Over | Under | |
|---|---|---|
| Austin Hays (CIN) | 0.5 +140 | 0.5 -185 |
| Tyler Stephenson (CIN) | 0.5 +170 | 0.5 -220 |
| Spencer Horwitz (TOR) | 0.5 +170 | 0.5 -225 |
| Oneil Cruz (PIT) | 0.5 +175 | 0.5 -235 |
| Elly De La Cruz (CIN) | 0.5 +180 | 0.5 -235 |
Pirates vs Reds Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Brady Singer (CIN) | 4.5 -150 | 4.5 +115 |
| Andrew Heaney (PIT) | 4.5 -115 | 4.5 -115 |
Reds Starting Pitcher Stats & Trends
Brady Singer has allowed a slugging percentage of .889 (16 Total Bases / 18 ABs) on low fastballs this season — highest among qualified SPs in MLB; League Avg: .406 — first Percentile.
Brady Singer has thrown inside pitches 55% of the time (267/483) vs left-handed batters this season — highest among among NL Starters; League Avg: 31% — 100th Percentile.
Opponents are hitting .351 against Brady Singer with RISP this season — second worst among qualified SPs– second Percentile. Opponents batted just .192 (29-for-151) against him with RISP last season — tied for sixth best among qualified SPs– 91st Percentile.
Brady Singer has thrown inside pitches 55% of the time (267/483) vs left-handed batters this season — highest among qualified SPs in MLB; League Avg: 31% — 100th Percentile.
Pirates Starting Pitcher Stats & Trends
Opponents have a groundball rate of just 37% (234/631) against Andrew Heaney since last season — 5th lowest among qualified SPs in MLB; League Avg: 43% — 10th Percentile.
Opponents are hitting just .125 (4-for-32) against Andrew Heaney’s elevated fastball this season — tied for 7th best among qualified SPs in MLB; League Avg: .217 — 90th Percentile.
Andrew Heaney has allowed an OPS of .788 (362 PA’s) when going through the lineup the second time in a game since last season — 3rd highest among qualified SPs in MLB; League Avg: .669 — sixth Percentile.
Andrew Heaney has not struck out any hitters in 18 PA’s when going through the lineup the second time in a game over the last 14 days — tied for lowest among NL Starters over the last two weeks; League Avg: 24% — third Percentile.
Reds Keys to the Game vs. the Pirates
The Reds were just 5-16 (.238) when tied entering the 8th inning in the 2024 season — lowest in MLB; League Avg: .500.
The Reds are just 6-18 (.250) when tied entering the 8th inning since last season — 2nd lowest in MLB; League Avg: .500.
The Reds are just 6-81 (.069) when trailing entering the 7th inning since last season — 2nd lowest in MLB; League Avg: .140.
The Reds are just 4-84 (.045) when trailing entering the 8th inning since last season — 2nd lowest in MLB; League Avg: .097.
Pirates Keys to the Game vs. the Reds
The Pirates are just 7-61 (.103) when allowing 10 or more hits since last season — 2nd lowest in MLB; League Avg: .251.
The Pirates are just 0-17 (.000) when allowing 10 or more hits this season — lowest in MLB; League Avg: .253.
The Pirates are just 11-41 (.212) when their opponents score in the first inning since last season — 2nd lowest in MLB; League Avg: .363.
The Pirates were just 7-44 (.137) when allowing 10 or more hits in the 2024 season — 2nd lowest in MLB; League Avg: .250.
Reds Hitting Stats & Trends
Reds hitters are slugging just .154 on pitches out of the zone since last season — lowest in MLB; League Avg: .203.
The Reds are batting just .117 on pitches out of the zone since last season — lowest in MLB; League Avg: .149.
Reds hitters are slugging just .170 on pitches out of the zone since the 2023 season — lowest in MLB; League Avg: .207.
The Reds batted just .116 on pitches out of the zone in the 2024 season — lowest in MLB; League Avg: .150.
Pirates Hitting Stats & Trends
Pirates hitters are slugging just .318 against RHP this season — lowest in MLB; League Avg: .402.
The Pirates are batting just .206 on the road this season — 2nd lowest in MLB; League Avg: .239.
Pirates hitters have grounded into 47 double plays in 338 opportunities (14%) this season — 2nd highest in MLB; League Avg: 9%.
Pirates hitters are slugging just .506 on the first pitch of at-bats since the 2023 season — lowest in MLB; League Avg: .577.
Reds Pitching Stats & Trends
Opponents have a groundball rate of just 39% against Reds pitchers since the 2023 season — lowest in MLB; League Avg: 43%.
Opponents had a groundball rate of just 39% against Reds pitchers in the 2024 season — lowest in MLB; League Avg: 43%.
Opponents have a groundball rate of just 39% against Reds pitchers since last season — lowest in MLB; League Avg: 43%.
Opponents had a groundball rate of just 39% against Reds pitchers in 2023 — 2nd lowest in MLB; League Avg: 43%.
Pirates Pitching Stats & Trends
Pirates pitchers have walked 6% of batters when facing the leadoff batter in the inning this season — 2nd best in MLB; League Avg: 8%.
Pirates pitchers have a strikeout rate of just 38% with two-strikes this season — 5th lowest in MLB; League Avg: 42%.
Batters facing the Pirates pitchers have struck out in the zone 55% of the time this season — tied for 3rd highest in MLB; League Avg: 50%. this season — tied for 3rd highest in MLB; League Avg: 50%.
The Pirates have won just 17% of home games in which their opponents scored first this season — 2nd lowest in MLB; League Avg: 40%.
More MLB Reading:
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