Royals vs Cardinals Prediction, Odds & Player Prop Bets Today – MLB, Jun 5

St. Louis Cardinals' Jordan Walker warms up before a baseball game against the Milwaukee Brewers Thursday, Sept. 28, 2023, in Milwaukee. (AP Photo/Aaron Gash)
(AP Photo/Aaron Gash)
  • The Cardinals are -125 favorites vs the Royals
  • Royals vs Cardinals Over / Under today: 8 Runs
  • Royals / Cardinals TV Channel: FDMW | FDKC

The Kansas City Royals (+105) visit Busch Stadium to take on the St. Louis Cardinals (-125) on Thursday, June 5, 2025. First pitch is scheduled for 7:45pm EDT in St. Louis, MO.

This season, the Royals are 32-29 against the spread (ATS), while the Cardinals are 35-25 ATS.

Royals vs Cardinals Starting Pitchers Today:

  • Royals starting pitcher: Cole Ragans 2-3, 4.57 ERA
  • Cardinals starting pitcher: Matthew Liberatore 3-4, 3.08 ERA

Royals vs. Cardinals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Royals+1.5 -190O 8 -102+105
Cardinals -1.5 +160U 8 -118-125

Royals vs Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the Cardinals will win Thursday‘s MLB game with 53.5% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Royals players for Thursday‘s game, looking at profitable historical betting trends:

Best Royals Player Prop Bets Today:

  • Salvador Perez has hit the Runs Under in 22 of his last 25 games (+15.95 Units / 37% ROI)
  • Vinnie Pasquantino has hit the Singles Over in 20 of his last 25 games (+15.20 Units / 56% ROI)
  • Vinnie Pasquantino has hit the Hits Over in 20 of his last 25 games (+10.95 Units / 22% ROI)
  • Maikel Garcia has hit the Hits Runs and RBIs Over in 12 of his last 15 games (+8.50 Units / 45% ROI)
  • Nick Loftin has hit the Home Runs Over in 1 of his last 4 games (+8.00 Units / 200% ROI)

And here are some favorite MLB player prop bets for Cardinals players for Thursday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today:

  • Alec Burleson has hit the Home Runs Over in 3 of his last 10 games at home (+15.40 Units / 154% ROI)
  • Alec Burleson has hit the Total Bases Over in 17 of his last 25 games (+11.05 Units / 33% ROI)
  • Nolan Arenado has hit the Hits Under in 12 of his last 20 games (+10.35 Units / 52% ROI)
  • Ivan Herrera has hit the Runs Under in his last 8 games (+8.00 Units / 59% ROI)
  • Victor Scott II has hit the Singles Over in 10 of his last 15 games at home (+7.95 Units / 53% ROI)
  • The Kansas City Royals have hit the Team Total Under in 44 of their last 61 games (+26.80 Units / 38% ROI)
  • The Kansas City Royals have hit the Game Total Under in 35 of their last 53 games (+16.20 Units / 28% ROI)
  • The Kansas City Royals have covered the Run Line in 15 of their last 17 away games (+12.10 Units / 44% ROI)
  • The Kansas City Royals have hit the Moneyline in 24 of their last 39 games (+11.20 Units / 22% ROI)
  • The Kansas City Royals have covered the 1st Five Innings (F5) Run Line in 14 of their last 17 away games (+10.25 Units / 48% ROI)
  • The St. Louis Cardinals have covered the Run Line in 20 of their last 27 games (+14.20 Units / 40% ROI)
  • The St. Louis Cardinals have hit the Moneyline in 24 of their last 37 games (+11.45 Units / 27% ROI)
  • The St. Louis Cardinals have hit the Team Total Over in 19 of their last 28 games at home (+9.57 Units / 30% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Over in 13 of their last 20 games at home (+4.98 Units / 21% ROI)
  • The St. Louis Cardinals have hit the Game Total Over in 9 of their last 15 games at home (+4.60 Units / 28% ROI)

Royals Against the Spread (ATS) Record

Against the spread this season, the Royals are 32-29 against the Run Line (-6.1 Units / -6.87% ROI).

  • 32-29 when betting on the Moneyline for +3.7 Units / 4.9% ROI
  • 22-38 when betting on the total runs Over for -19.22 Units / -28.94% ROI
  • 38-22 when betting on the total runs Under for +13.7 Units / 20.21% ROI

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 35-25 against the Run Line (+5.4 Units / 6.46% ROI).

  • 33-27 when betting on the Moneyline for +5.8 Units / 8.5% ROI
  • 32-25 when betting on the total runs Over for +4.5 Units / 6.83% ROI
  • 25-32 when betting on the total runs Under for -10.4 Units / -15.72% ROI

Cardinals vs Royals Home Run Prop Bets Today

Over Under
Bobby Witt Jr. (KC) 0.5 +400 0.5 -550
Willson Contreras (STL) 0.5 +525 0.5 -750
Lars Nootbaar (STL) 0.5 +525 0.5 -750
Vinnie Pasquantino (KC) 0.5 +525 0.5 -750
Masyn Winn (STL) 0.5 +550 0.5 -800

Cardinals vs Royals Total Hits Prop Bets Today

Over Under
Salvador Perez (KC) 0.5 -275 0.5 +195
Vinnie Pasquantino (KC) 0.5 -275 0.5 +195
Masyn Winn (STL) 0.5 -250 0.5 +185
Jonathan India (KC) 0.5 -250 0.5 +190
Brendan Donovan (STL) 0.5 -250 0.5 +190

Cardinals vs Royals RBI Prop Bets Today

Over Under
Vinnie Pasquantino (KC) 0.5 +130 0.5 -165
Bobby Witt Jr. (KC) 0.5 +155 0.5 -210
Willson Contreras (STL) 0.5 +160 0.5 -210
Salvador Perez (KC) 0.5 +160 0.5 -210
Ivan Herrera (STL) 0.5 +165 0.5 -220

Cardinals vs Royals Strikeout Prop Bets Today

Over Under
Miles Mikolas (STL) 2.5 -155 2.5 +120
Noah Cameron (KC) 3.5 -130 3.5 +100

Opponents had a miss rate of 32% (488/1,526) against Cole Ragans in the 2024 season — 3rd best among qualified SPs in MLB; League Avg: 26% — 96th Percentile.

Opposing hitters have a miss rate of 41% (30/74) against Cole Ragans when he’s behind in the count this season — best in MLB among starting pitchers with at least 24 total IP; League Avg: 23% — 100th Percentile.

Cole Ragans has a strikeout rate of 38% (72 SO in 191 PAs) this season — best in MLB among starting pitchers with at least 24 total IP; League Avg: 22% — 100th Percentile.

Cole Ragans has a strikeout rate of 31% (295 SO in 953 PAs) since last season — 4th best among qualified SPs in MLB; League Avg: 24% — 93rd Percentile.

Cardinals Starting Pitcher Stats & Trends

Matthew Liberatore has walked 1% of batters when going through the lineup the second time in a game this season — 2nd best among qualified SPs in MLB; League Avg: 7% — 98th Percentile.

Matthew Liberatore has walked 2% of right-handed batters this season — best among qualified SPs in MLB; League Avg: 7% — 100th Percentile.

Opposing hitters have a chase rate of 40% (30/76) against Matthew Liberatore when he’s behind in the count this season — highest among qualified SPs in MLB; League Avg: 25% — 100th Percentile.

Matthew Liberatore walked 4 of 138 left-handed batters (3%) in the 2024 season — 4th best among qualified RPs in MLB; League Avg: 9% — 96th Percentile.

Royals Keys to the Game vs. the Cardinals

The Royals were just 4-50 (.074) when they allowed 5 or more runs in the 2024 season — 2nd lowest in MLB; League Avg: .196.

The Royals are just 19-90 (.174) when allowing 2 or more home runs since the 2023 season — 2nd lowest in MLB; League Avg: .298.

The Royals are 10-1 (.909) when scoring 5 or more runs this season — tied for 3rd best in MLB; League Avg: .813.

The Royals are just 24-69 (.258) when their opponents score in the first inning since the 2023 season — 3rd lowest in MLB; League Avg: .374.

Cardinals Keys to the Game vs. the Royals

The Cardinals are just 0-19 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .093.

The Cardinals are just 1-18 (.053) when trailing entering the 7th inning this season — 4th lowest in MLB; League Avg: .135.

The Cardinals are 22-14 (.611) when tied entering the 7th inning since last season — 5th best in MLB; League Avg: .499.

The Cardinals are just 6-83 (.067) when trailing entering the 8th inning since last season — tied for 5th lowest in MLB; League Avg: .098.

Royals hitters have struck out in just 19% of it’s PA’s against RHP since last season — 2nd best in MLB; League Avg: 22%.

Royals hitters have an OBP of just .289 (7,105 PA’s) on the road since the 2023 season — 3rd lowest in MLB; League Avg: .312.

Royals hitters struck out just 863 times in 4,480 PA’s (19%) against RHP in the 2024 season — 3rd best in MLB; League Avg: 23%.

Royals hitters have struck out in just 18% of it’s PA’s against RHP this season — best in MLB; League Avg: 22%.

Cardinals hitters have an OPS of .740 (1,624 PA’s) against RHP this season — 5th best in MLB; League Avg: .718.

Cardinals hitters have an OBP of .352 (1,047 PA’s) at home this season — 2nd best in MLB; League Avg: .321.

The Cardinals are batting .282 at home this season — tied for best in MLB; League Avg: .248.

The Cardinals are batting .178 on pitches out of the zone this season — best in MLB; League Avg: .147.

The longest HR allowed by the Royals pitchers in the 2024 season traveled 519.4 feet — — longest in MLB; League Avg: 470.4

Royals pitchers picked-off 19 runners from first base in 2023 — best in MLB.

Royals pitchers had an ERA of 2.97 (460.2 IP) against division opponents in the 2024 season — 2nd best in MLB; League Avg: 4.06.

Royals pitchers have walked 8% of batters this season — 4th best in MLB; League Avg: 9%.

Opponents have a miss rate of just 23% against Cardinals pitchers since the 2023 season — 2nd lowest in MLB; League Avg: 25%.

Opponents had a miss rate of just 23% against Cardinals pitchers in 2023 — 2nd lowest in MLB; League Avg: 26%.

Cardinals pitchers had a strikeout rate of just 38% with two-strikes in 2023 — tied for 2nd lowest in MLB; League Avg: 43%.

Opponents have a miss rate of just 22% against Cardinals pitchers this season — lowest in MLB; League Avg: 25%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.