Twins vs Cardinals Prediction, Odds & Player Prop Bets Today – MLB, Mar 29

MLB betting odds, predictions and betting odds for today's games
(AP Photo)
  • The Twins are -125 favorites vs the Cardinals
  • Twins vs Cardinals Over / Under today: 7.5 Runs
  • Twins / Cardinals TV Channel: FS1 | TWTV | FDMW

The Minnesota Twins (-120) visit Busch Stadium to take on the St. Louis Cardinals (+100) on Saturday, March 29, 2025. First pitch is scheduled for 2:15pm EDT in St. Louis, MO.

This season, the Twins are 0-0 against the spread (ATS), while the Cardinals are 0-0 ATS.

Twins vs Cardinals Starting Pitchers Today:

  • Twins starting pitcher: Joe Ryan 0-0, 0.00 ERA
  • Cardinals starting pitcher: Erick Fedde 0-0, 0.00 ERA

Twins vs. Cardinals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Twins-1.5 +145O 7.5 -110-120
Cardinals +1.5 -175U 7.5 -110+100

Twins vs Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the Twins will win Saturday‘s MLB game with 52.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Twins players for Saturday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Bets Today:

  • Joe Ryan has hit the Pitching Outs Under in 6 of his last 7 games (+5.80 Units / 53% ROI)
  • Joe Ryan has hit the Strikeouts Under in 13 of his last 20 games (+4.90 Units / 21% ROI)
  • Joe Ryan has hit the Earned Runs Over in 5 of his last 6 games (+3.95 Units / 46% ROI)
  • Joe Ryan has hit the Walks Allowed Under in 8 of his last 10 games (+3.85 Units / 21% ROI)
  • Joe Ryan has hit the Hits Allowed Under in his last 3 games (+3.05 Units / 84% ROI)

And here are some favorite MLB player prop bets for Cardinals players for Saturday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today:

  • Erick Fedde has hit the Earned Runs Under in 16 of his last 25 games (+6.50 Units / 22% ROI)
  • Erick Fedde has hit the Pitching Outs Under in 5 of his last 6 games at home (+4.40 Units / 67% ROI)
  • Erick Fedde has hit the Walks Allowed Over in 5 of his last 6 games at home (+3.65 Units / 42% ROI)
  • Erick Fedde has hit the Hits Allowed Under in 6 of his last 9 games at home (+3.40 Units / 34% ROI)
  • Erick Fedde has hit the Strikeouts Under in his last 3 games at home (+3.00 Units / 83% ROI)
  • The Minnesota Twins have hit the Game Total Over in 55 of their last 96 games (+16.90 Units / 16% ROI)
  • The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Under in their last 4 games (+4.20 Units / 79% ROI)
  • The Minnesota Twins have covered the Run Line in 3 of their last 6 away games (+0.35 Units / 5% ROI)
  • The St. Louis Cardinals have covered the Run Line in 26 of their last 41 games (+9.15 Units / 16% ROI)
  • The St. Louis Cardinals have hit the Game Total Under in 18 of their last 27 games at home (+9.10 Units / 31% ROI)
  • The St. Louis Cardinals have hit the Moneyline in 22 of their last 37 games (+8.90 Units / 21% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 14 of their last 21 games at home (+7.35 Units / 30% ROI)

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are 0-0 against the Run Line (+0 Units / 0% ROI).

  • 0-0 when betting on the Moneyline for +0 Units / 0% ROI
  • 0-0 when betting on the total runs Over for +0 Units / 0% ROI
  • 0-0 when betting on the total runs Under for +0 Units / 0% ROI

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 0-0 against the Run Line (+0 Units / 0% ROI).

  • 0-0 when betting on the Moneyline for +0 Units / 0% ROI
  • 0-0 when betting on the total runs Over for +0 Units / 0% ROI
  • 0-0 when betting on the total runs Under for +0 Units / 0% ROI

Cardinals vs Twins Home Run Prop Bets Today

Over Under
Matt Wallner (MIN) 0.5 +350 0.5 -450
Byron Buxton (MIN) 0.5 +375 0.5 -500
Willson Contreras (STL) 0.5 +500 0.5 -700
Lars Nootbaar (STL) 0.5 +600 0.5 -900
Trevor Larnach (MIN) 0.5 +625 0.5 -1000

Cardinals vs Twins Total Hits Prop Bets Today

Over Under
Ty France (MIN) 0.5 -235 0.5 +175
Byron Buxton (MIN) 0.5 -235 0.5 +180
Trevor Larnach (MIN) 0.5 -200 0.5 +155
Lars Nootbaar (STL) 0.5 -200 0.5 +150
Alec Burleson (STL) 0.5 -200 0.5 +155

Cardinals vs Twins RBI Prop Bets Today

Over Under
Byron Buxton (MIN) 0.5 +135 0.5 -175
Trevor Larnach (MIN) 0.5 +175 0.5 -235
Ty France (MIN) 0.5 +190 0.5 -250
Jose Miranda (MIN) 0.5 +195 0.5 -275
Matt Wallner (MIN) 0.5 +200 0.5 -275

Cardinals vs Twins Strikeout Prop Bets Today

Over Under
Joe Ryan (MIN) 4.5 -155 4.5 +120
Erick Fedde (STL) 4.5 -130 4.5 +100

Joe Ryan has a strike rate of 70% (1,550/2,210) vs left-handed batters since the 2023 season — highest in MLB among starting pitchers with at least 129 total IP; League Avg: 64% — 100th Percentile.

Left-handed hitters had a swing rate of 57% (708/1,249) against Joe Ryan in 2023 — highest in MLB among starting pitchers with at least 64 total IP; League Avg: 47% — 100th Percentile.

Joe Ryan had a strike rate of 69% (1,849/2,683) in 2023 — tied for 3rd highest among qualified SPs in MLB; League Avg: 65% — 95th Percentile.

Opponents had a groundball rate of just 33% (144/435) against Joe Ryan in 2023 — 3rd lowest among qualified SPs in MLB; League Avg: 43% — sixth Percentile.

Cardinals Starting Pitcher Stats & Trends

Erick Fedde has a strike rate of just 57% (522/908) in two strike counts since last season — 2nd lowest among qualified SPs in MLB; League Avg: 65% — third Percentile.

Erick Fedde had a strike rate of just 57% (522/908) in two strike counts in the 2024 season — 2nd lowest among qualified SPs in MLB; League Avg: 65% — third Percentile.

Erick Fedde has a strike rate of just 50% (539/1,077) when ahead in the count since last season — 2nd lowest among qualified SPs in MLB; League Avg: 61% — third Percentile.

Hitters swung at 53% of Erick Fedde’s pitches (478/908) with two-strikes in the 2024 season — 2nd lowest among qualified SPs in MLB; League Avg: 60% — third Percentile.

Twins Keys to the Game vs. the Cardinals

The Twins are 140-2 (.986) when leading entering the 9th inning since the 2023 season — best in MLB; League Avg: .949.

The Twins are 62-26 (.705) when they’ve scored in the first inning since the 2023 season — 4th best in MLB; League Avg: .626.

The Twins were just 1-68 (.014) when trailing entering the 9th inning in 2024 — 3rd lowest in MLB; League Avg: .050.

The Twins were just 15-28 (.349) vs top 10 scoring offenses in 2024 They play the Marlins (27th best runs scored) today.

Cardinals Keys to the Game vs. the Twins

The Cardinals were 18-9 (.667) when tied entering the 7th inning in 2024 — tied for 3rd best in MLB; League Avg: .500.

The Cardinals are 24-17 (.585) when tied entering the 8th inning since the 2023 season — 5th best in MLB; League Avg: .500.

The Cardinals are just 46-50 (.479) vs bottom 10 scoring offenses since the 2023 season They play the Rockies (19th best runs scored) today.

The Cardinals are 29-18 (.617) when tied entering the 7th inning since the 2023 season — 3rd best in MLB; League Avg: .500.

Twins hitters slugged .716 on the first pitch of at-bats in 2023 — 2nd best in MLB; League Avg: .596.

Twins hitters struck out 380 times in 1,509 PA’s (25%) against LHP in 2023 — tied for 4th highest in MLB; League Avg: 23%.

Twins hitters put just 33% of their swings in play with two-strikes in 2023 — tied for lowest in MLB; League Avg: 37%.

Twins hitters struck out 1,654 times in 6,219 PA’s (27%) in 2023 — highest in MLB; League Avg: 23%.

Cardinals hitters have just 351 strikeouts in 1,755 PA’s (20%) against LHP since last season — 5th best in MLB; League Avg: 23%.

Cardinals hitters struck out just 351 times in 1,755 PA’s (20%) against LHP in the 2024 season — tied for 5th best in MLB; League Avg: 23%.

The Cardinals are batting .180 with two-strikes since last season — 5th best in MLB; League Avg: .168.

The Cardinals won only 43% of their home games in the 2023 season — 5th lowest in MLB; League Avg: 52%.

Twins pitchers induced opposing hitters to ground into just 70 double plays in 1,033 opportunities (7%) in the 2024 season — lowest in MLB; League Avg: 10%.

Twins pitchers have walked 878 of 12,141 batters (7%) since the 2023 season — 2nd best in MLB; League Avg: 8%.

Twins pitchers have a strikeout rate of 26% when facing the leadoff batter in the inning since the 2023 season — best in MLB; League Avg: 23%.

Twins pitchers have walked 435 of 6,113 batters (7%) since last season — 3rd best in MLB; League Avg: 8%.

Cardinals pitchers had a strikeout rate of just 38% with two-strikes in 2023 — tied for 2nd lowest in MLB; League Avg: 43%.

Opponents have a miss rate of just 23% against Cardinals pitchers since the 2023 season — 2nd lowest in MLB; League Avg: 26%.

Cardinals pitchers had a strikeout rate of just 19% in 2023 — 2nd lowest in MLB; League Avg: 23%.

Opponents had a miss rate of just 23% against Cardinals pitchers in 2023 — 2nd lowest in MLB; League Avg: 26%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.